2023
DOI: 10.1089/ars.2022.0008
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NEAT1 Regulates Calcium Oxalate Crystal-Induced Renal Tubular Oxidative Injury via miR-130/IRF1

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Cited by 11 publications
(3 citation statements)
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“…Inflammation-induced by calcium oxalate crystals promotes tissue damage, renal cell injury, and recruitment of more inflammatory cells, further exacerbating the inflammatory process [ 21 ]. In addition, calcium oxalate crystals can generate ROS directly or indirectly, leading to activation of NADPH oxidase and mitochondrial dysfunction, which finally cause renal cell apoptosis [ 22 ]. Repressing the release of pro-inflammatory cytokines, such as IL-1β, TNF-α, IL-6, and oxidative stress mediators, such as ROS, and MDA, can markedly relieve pain and cell apoptosis in kidney stones [ 23 , 24 ].…”
Section: Discussionmentioning
confidence: 99%
“…Inflammation-induced by calcium oxalate crystals promotes tissue damage, renal cell injury, and recruitment of more inflammatory cells, further exacerbating the inflammatory process [ 21 ]. In addition, calcium oxalate crystals can generate ROS directly or indirectly, leading to activation of NADPH oxidase and mitochondrial dysfunction, which finally cause renal cell apoptosis [ 22 ]. Repressing the release of pro-inflammatory cytokines, such as IL-1β, TNF-α, IL-6, and oxidative stress mediators, such as ROS, and MDA, can markedly relieve pain and cell apoptosis in kidney stones [ 23 , 24 ].…”
Section: Discussionmentioning
confidence: 99%
“…6 Some lncRNAs, including MALAT1, TUG, NEAT1 and HNF1A-AS1, are reported to be dysregulated in CRC, playing a role in regulating the development and progression of intestinal cancer. [7][8][9][10] N6-methyladenosine (m6A) is the most prevalent modification found in eukaryotic RNA. 11 The process of RNA m6A methylation is dynamic and reversible, and involves three types of proteins: methyltransferases, recognition proteins and demethyltransferases.…”
Section: Introductionmentioning
confidence: 99%
“…Despite many research results that need to be further verified, lncRNAs can play diverse functions in cancer carcinogenesis, metastasis and poor prognosis 6 . Some lncRNAs, including MALAT1, TUG, NEAT1 and HNF1A‐AS1, are reported to be dysregulated in CRC, playing a role in regulating the development and progression of intestinal cancer 7–10 …”
Section: Introductionmentioning
confidence: 99%