Nécrobiose lipoïdique sur sein reconstruit par implant en silicone : à propos d’un cas

Necrobiosis lipoidica of the breast associated with Crohn’s disease: a case report

“…To the best of our knowledge, there are only three published cases of necrobiotic skin lesions on the lower leg resembling erythema nodosum in MCD [ 8 , 9 ], which is different from the skin lesions in our patient that are more characteristic of NL of the breast. This location of NL on the breast is extremely rare, as it was reported in only one case a few months following the insertion of a silicone implant (post-mastectomy reconstruction) [ 10 ].…”

Necrobiosis Lipoidica following Breast Reduction

“…19 The time interval between trauma/surgery and the development of NL ranges from a few months to 10 years. 4–9…”

“…Only two cases have been published in the English literature, following breast reconstruction surgery. 8,9…”

“…A link between NL and the Köbner effect on traumatized skin has been well established, with previous reports of NL developing on sites of insulin injections, burns, or surgical scars. [4][5][6][7][8][9] However, it has been suggested that because NL sometimes develops on scar tissue without a previous history of NL elsewhere on the skin, it might sometimes present as a Wolf's isomorphic response. The latter is defined as a new skin disease occurring at the site of a previously healed dermatosis or as a manifestation of Ruocco's "immunocompromised cutaneous district" in which a harmful event induces a local immune dysregulation that makes the skin susceptible to immune-mediated skin disorders.…”

“…Only two cases have been published in the English literature, following breast reconstruction surgery. 8,9 The treatment of NL is very challenging and notoriously difficult. An adequate control of glucose does not affect the evolution of NL but should always be aimed to prevent other complications of DM.…”