Necrotizing Sialometaplasia and Bulimia: A Case Report

Abstract

Bulimia is an eating disorder with a great prevalence in young women. Due to its multifactor ethiology, bulimia has systemic consequences. In the literature, necrotising sialometaplasia is seldom associated with bulimia. Its etiopathogenesis is discussed by several authors; nevertheless, the consensus does not consider the relevance of local trauma associated with induced vomiting. A case of necrotising sialomethaplasia, presented with a single hard palatal ulcer in a bulimic woman is described in the present report. The patient did not present significant systemic laboratorial values, nor physical weight variations, which highlights the relevance of performing a complete medical clinical history when diagnosing this rare pathology.

Necrotizing Sialometaplasia: A Diagnostic Puzzle for Clinicians

“…Recently, studies have presented a few cases that occurred in relation to anorexia or bulimia [6,7].…”

Necrotizing Sialometaplasia: A Diagnostic Challenge to Oral Physicians

“…The adrenaline in local anesthetic causes localized vasoconstriction and ischemia, which results in its formation. [ 2 ] Trauma from intubation procedure for general anesthesia also can result in necrotizing sialometaplasia, bulimia nervosa, an eating disorder with marked binge eating followed by purging [ 3 , 4 ]. Gatti A et al described a necrotizing sialometaplasia caused by excessive use of the nonsteroidal anti-inflammatory drug Flurbiprofen oral spray that contained alcohol six times once a day for five weeks for prevention of sore throat [ 5 ].…”

Histopathological significance of necrosis in oral lesions: A review

“…The coagulation-induced necrosis of glandular acini and squamous metaplasia of its ducts are the microscopic characteristics of NS. [ 20 ] There is mucin pooling, and the inflammatory infiltration is composed of neutrophils, macrophages, and less frequently, lymphocytes, plasma cells, and eosinophils. [ 20 ]…”

“…[ 20 ] There is mucin pooling, and the inflammatory infiltration is composed of neutrophils, macrophages, and less frequently, lymphocytes, plasma cells, and eosinophils. [ 20 ]…”