Necrotizing sialometaplasia – Case report

Wu, Yu-Hsueh; Kuo, Ying-Shiung; Lin, Ping‐Yi; Chiang, Chun‐Pin

doi:10.1016/j.jds.2020.03.001

Cited by 6 publications

(4 citation statements)

References 5 publications

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“…Although necrotising sialometaplasia is considered a rare inflammatory condition, similar findings have been reported across the globe 9 10. Synchronous and bilateral lesions have been reported by Zhurakivska et al , Joshi et al and Neri et al 11–13…”

Section: Discussionsupporting

confidence: 63%

Diagnostic dilemma: our experience with necrotising sialometaplasia

2023

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A man in his 40s presented to our outpatient department with a painful ulcer in the oral cavity for 1 week. After intraoral examination, a single hard palate ulcer, which was non-tender on palpation, was noted. Baseline blood investigations such as haemogram and serological evaluation were within normal limits. Under local anaesthesia, an excisional biopsy was performed. The histopathological examination revealed a reactive necrotising inflammatory process involving minor salivary glands with no cytological atypia. Weekly follow-up was performed and at the end of 4 weeks, complete healing of the lesion had occurred without any further intervention.

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Section: Discussionsupporting

confidence: 63%

Diagnostic dilemma: our experience with necrotising sialometaplasia

2023

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“…The adrenaline in local anesthetic causes localized vasoconstriction and ischemia, which results in its formation. [ 2 ] Trauma from intubation procedure for general anesthesia also can result in necrotizing sialometaplasia, bulimia nervosa, an eating disorder with marked binge eating followed by purging [ 3 , 4 ]. Gatti A et al described a necrotizing sialometaplasia caused by excessive use of the nonsteroidal anti-inflammatory drug Flurbiprofen oral spray that contained alcohol six times once a day for five weeks for prevention of sore throat [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

Necrotizing Sialometaplasia: A Diagnostic Challenge to Oral Physicians

Senthilnathan¹,

Mohan²,

Fenn³

et al. 2022

Cureus

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Necrotizing sialometaplasia is a rare, reactive, self-limiting disorder affecting a minor salivary gland that clinically mimics malignancy. Chronic smoking, alcohol use, trauma to the hard palate caused by local anesthetic injection due to the vasoconstrictive action of adrenaline in local anesthetic, topical application of nonsteroidal anti-inflammatory drugs like flurbiprofen spray used in bronchial asthma, oral intubation procedures for general anesthesia, ill-fitting dentures, bulimia nervosa, and minor salivary gland tumors are some of the contributing factors linked to its development. In this article, we discuss a rare, reactive, selflimiting condition affecting minor salivary gland, necrotizing sialometaplasia that occurred on the right posterolateral hard palate region in a 57-year-old male chronic smoker, diagnosed by oral medicine specialist by clinical findings and radiological evaluation by cone beam computed tomography that healed rapidly in three days by itself without any treatment, that prevented unwanted biopsy or surgery.

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“…Recurrences are not frequent, but SMN indicates an aggression to the oral mucosa. The triggering factor should be suppressed to facilitate regression of the lesion and avoid its evolution to other pathologies with a worse prognosis, especially tobacco and alcohol, the main risk factors for head and neck cancer [5][6][7].…”

Section: Discussionmentioning

confidence: 99%

"Necrotizing Sialometaplasia: Importance of Differential Diagnosis Versus Malignancy"

Valle¹

2022

BJSTR

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Necrotizing sialometaplasia – Case report

Cited by 6 publications

References 5 publications

Diagnostic dilemma: our experience with necrotising sialometaplasia

Diagnostic dilemma: our experience with necrotising sialometaplasia

Necrotizing Sialometaplasia: A Diagnostic Challenge to Oral Physicians

"Necrotizing Sialometaplasia: Importance of Differential Diagnosis Versus Malignancy"

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