Necrotizing Sialometaplasia Masquerading as Residual Cancer of the Lip

Granick, Mark S.; Solomon, Mark P.; Benedetto, Anthony V.; Hannegan, Michael W.; Sohn, Min

doi:10.1097/00000637-198808000-00012

Cited by 9 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Necrotizing sialometaplasia (NS) is an uncommon but benign and self‐limiting disorder. A correct diagnosis is mandatory since NS may clinically and histologically simulate malignancy, such as squamous cell carcinoma or mucoepidermoid carcinoma (Anneroth, Bystedt, & Hammarstrom, ; Coley‐Smith & Ellis, ; Gad, Willen, Willen, Thorstensson, & Ekman, ; Granick, Solomon, Benedetto, Hannegan, & Sohn, ; Joshi, Halli, Koranne, & Singh, ; Poulson, Greer, & Ryser, ; Santis, Kabani, Roderiques, & Driscoll, ), possibly resulting in unnecessary radical surgery (Fechner, ). Indeed, goblet cells may occur within the metaplastic squamous cell, thus suggesting an inaccurate diagnosis of mucoepidermoid carcinoma (Birkholz, Minton, & Yuen, ; Donath & Seifert, ; Fechner, ; Gahhos et al, ; Lynch, Crago, & Martinez, ; Myers, Bankaci, & Barnes, ; Raugi & Kessler, ; Santis et al, ; Taxy, ).…”

Section: Discussionmentioning

confidence: 99%

Necrotizing sialometaplasia can hide the presence of salivary gland tumors: A case series

et al. 2019

View full text Add to dashboard Cite

Objective Necrotizing sialometaplasia (NS) is an uncommon benign process which affects minor and, more rarely, major salivary glands. While self‐limiting, the condition might be clinically and histologically mistaken for malignancy. Furthermore, NS may accompany neoplasms. The aim of this paper was to report a series of Italian patients affected by NS associated with an unusual high presence of neoplasms of minor and major salivary glands. Study Design Clinical and histological features of twelve patients with NS were retrospectively evaluated. Results Eight patients presented NS of the minor salivary glands of the palate, and two of them had associated neoplasms (pleomorphic adenoma and adenoid cystic carcinoma) at the same site. Four patients had NS of the parotid gland associated with a history of fine‐needle aspiration biopsy performed to diagnose parotid neoplasms. These were epithelial–myoepithelial carcinoma, adenoid cystic carcinoma, Warthin's tumor, and oncocytoma, respectively. Conclusion Tumors of minor and major salivary glands might be associated with NS more frequently than previously reported. While NS of the parotid is generally the result of invasive diagnostic procedure and is detected after the excision of the tumor, NS of the minor salivary glands may obscure an underlying neoplasm, resulting in delays in referral or treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Necrotizing sialometaplasia can hide the presence of salivary gland tumors: A case series

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Dans d'autres cas, un facteur traumatique (physique, chimique, thermique…) précédant la survenue de la SMN a été retrouvé : injections d'anesthésiques locaux et usage de produits chimiques lors des soins dentaires [15,[17][18][19][20][21][22][23], ingestion de boissons chaudes [24], port de prothèses dentaires [3, 8-11, 18, 21, 23, 25-39], intervention chirurgicale loco-régionale [18][19][20][21][22][23][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54]. Quelquefois, une tumeur des voies aéro-digestives supérieures susceptible de créer des modifications vasculaires loco-régionales était associée à la SMN [8, 10, 16, 23, 28, 38, 40-43, 45-48, 50, 53, 55-61].…”

Section: Théorie Vasculaireunclassified

“…Un cas faisant suite à un eczéma de contact à la néomycine a été rapporté [47]. 3 % des cas présentaient des allergies, médicamenteuses ou non [12,47,49,80,83,88].…”

Section: Théorie Allergiqueunclassified

La sialométaplasie nécrosante : revue systématique de la littérature

Aubies-Trouilh¹,

Fricain²

2012

Med Buccale Chir Buccale

View full text Add to dashboard Cite

Résumé -Objectif :Répertorier les caractéristiques épidémiologiques, étiopathogéniques, cliniques, histologiques et thérapeutiques de la sialométaplasie nécrosante (SMN). Results: NSM is an uncommon benign disease of salivary glands. Usually, NSM affects the minor salivary glands of the hard palate. It occurs primarily in adults, NSM is manifested by a sharply demarcated crater-like palatal ulcer. Although the etiology is uncertain, the lesion heals spontaneously. Conclusion: Dental surgeon has to know this lesion because of the risk of histological and clinical confusion with malignant lesions which may lead to mutilating radical treatment.

show abstract

“…59,60 Necrotizing sialometaplasia and Sweet syndrome can appear clinically as SC or SCC. 61,62 Necrotizing sialometaplasia is a benign lesion of the salivary glands that may occur on the lower lip, but the histology is definitively diagnostic. 63 Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is characterized by the acute onset of well demarcated plaques.…”

Section: Photodermatoses and Other Disorders Of The Lower Lipmentioning

confidence: 99%