Needle-Type Glucose Sensor Based on Functionalized Graphene

Abstract

We demonstrate a novel, highly efficient glucose sensor based on functionalized graphene. Glucose oxidase (GOD) immobilization has been apprehendedbythe direct interaction between carboxyl acid groups of the reduced graphene oxide (RGO) and amines of GOD together with the electrostatic interactions existing between the positively charged polymeric ionic liquid (PIL) and GOD. This combined system can provide a favorable microenvironment for the GOD to retain its good bioactivity. The enzyme-coated graphene biosensor exhibited glucose-dependent electrochemical measurements against an Ag/AgCl reference electrode. The resulting sensor show broad range detection, up to 100 mM glucose concentration, with a sensitivity of 5.59 µA/ decade. It was found that glucose biosensor based on functionalized graphene can be seen as an effective candidate for the detection of sugar concentration in clinical diagnoses.

Functionalized Carbon Materials for Electronic Devices: A Review

“…An identical electrochemical biosensor containing Lac exhibited the ability to detect minute amounts of catechol in unique water conditions. On the other hand, Hassan et al [93] investigated a unique, effective glucose biosensor above functionalized rGO. This biosensor had a glucose-dependent electro-chemical behavior with Ag-AgCl as the standard electrode.…”

“…The modified biosensor electrode was developed by polishing a glass carbon electrode (GCE) with alumina and coating the GCE with the PDA-Lac-rGO-Pd hybrid material. Hassan et al [93] also prepared a functionalized graphene-based glucose sensor through the immobilization method. The GO was prepared by a modified Hummers’ method using graphite flakes, while the functionalization and reduction of GO were performed by adding PIL and hydrazine [94].…”

An Overview of the Latest Graphene‐Based Sensors for Glucose Detection: the Effects of Graphene Defects

“…Hasan et al [32] demonstrated a novel and efficient glucose biosensor based on functionalized graphene, deposited on a needle-like Pt electrode. The assembling of the biosensor is a clear example of the role of residual oxidation groups on graphene.…”

Ανάπτυξη Χημικών Αισθητήρων Για Την Ανίχνευση Τοξικών Ουσιών

“…Περιέχει μεγάλες ποσότητες ομάδων που περιέχουν οξυγόνο, το οποίο μπορεί να είναι επωφελής για τη λειτουργία μέσω της δράσης των βιομορίων για τα γεγονότα βιοαναγνώρισης κατά τη βιοανίχνευση. Οι ανηγμένες μορφές GO έχουν ένα μερικώς αποκαταστημένο πλέγμα sp 2 , καθώς και εξακολουθούν να κατέχουν κάποιο μέρος ομάδων που περιέχουν οξυγόνο(ul Hasan et al 2012). Ως εκ τούτου, θα μπορούσε κανείς να έχει πολλές επιλογές για να επιλέξει το σωστό τύπο του γραφενίου για σωστή εφαρμογή και μηχανισμό μετάλλαξης(Pumera 2011).…”

“…Οι Wang κ.ά. έχουν κατασκευάσει το σύνθετο ηλεκτρόδιο αποτελούμενο από γραφενίο και θειούχο κάδμιο για το βέλτιστο μικροπεριβάλλον για Οι ul Hasan κ.ά (ul Hasan et al 2012…”