Neonatal arterial thrombus mimicking congenital heart disease

A case of neonatal arterial thrombosis mimicking interrupted aortic arch

“…When we screened the literature, we found 10 cases where AC or IA was considered initially, but a diagnosis of aortic thrombosis was made subsequently (Table 1) (3)(4)(5)(6)(7)(8)(9)(10)(11). In 9 of these 10 patients, the symptoms started in the first 48 hours of life as in our patient.…”

Prenatal ductal thrombosis presenting as cyanotic heart lesion

“…The optimal treatment is determined by clinical factors, including the infant's condition, risk of bleeding, degree of organ damage and surgical expertise. 1 In all four of the previous case reports, systemic anticoagulation was attempted, but two of the neonates required surgical removal of the thrombosis after failed anticoagulation therapy. In our case, use of thrombolytic therapy was considered but not initiated because risk of hemorrhage outweighed the perceived benefit.…”

“…1 Most infants present with evidence of arterial insufficiency including limb ischemia, or if associated with umbilical artery catheterization, the thrombosis may mimic coarctation of the aorta. 1 Arterial thrombosis is only infrequently reported with a presentation suggestive of other congenital heart defects. We present a case of an infant who was suspected of having cyanotic heart disease, but was found to have a perinatal occlusive thrombosis of the ductus arteriosus.…”

Pulmonary Artery Thrombus Presenting as Cyanotic Cardiac Defect in a Neonate

“…The prevalence of symptomatic neonatal arterial thrombosis is approximately 1 in 40,000 births, with 90% of cases linked to indwelling intra-arterial catheters (1)(2)(3). Other risk factors are sepsis, polycythemia, maternal diabetes, asphyxia, and inherited thrombophilias (1)(2)(3).…”