Neonatal Coccidioidomycosis in a Southwestern Pima Indian

Cr, Westley; Haak, Wolfgang

doi:10.1097/00007611-197407000-00025

Cited by 12 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Coccidioidomycosis in infants younger than 1 month of age is rare, and it has been more than 2 decades since the last published case report. [13][14][15][16][17][18][19][20][21] We identified 3 cases of neonatal coccidioidomycosis at our institution over a 6-year period. In our patients, symptoms started within the first 1-4 weeks of life, but coccidioidomycosis was not diagnosed until months later, similar to what has been reported previously.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Neonatal Coccidioidomycosis

Vaughn

Tablizo

Zayed

et al. 2021

Pediatric Infectious Disease Journal

View full text Add to dashboard Cite

Background: Coccidioidomycosis is common in adult and pediatric populations living in endemic areas of the United States but has rarely been reported in neonates. We reviewed recent cases of neonatal coccidioidomycosis treated at a tertiary care children’s hospital in an endemic area and compared them with previously reported cases in the literature. Methods: We performed a retrospective chart review of infants 1 month old or less hospitalized with a diagnosis of coccidioidomycosis from January 1, 2014, to December 31, 2019. Additionally, we performed a literature review of all reported cases of neonatal coccidioidomycosis over the past 7 decades through PubMed. Infants born to mothers with confirmed or suspected active coccidioidomycosis were excluded. Results: Three cases of neonatal coccidioidomycosis were identified at our institution. Each presented in a unique manner and had an alternative diagnosis at the time of initial presentation. Two patients had negative coccidioidal screening tests upon admission but later seroconverted. All patients had extrapulmonary involvement, and all recovered after appropriate treatment. A review of the literature reveals that the presentations and outcomes of neonatal coccidioidomycosis vary widely. Conclusions: There is significant variability in the presentation of coccidioidomycosis in the neonatal period, and diagnosis may be challenging. In endemic regions, healthcare providers should consider coccidioidomycosis in their differential diagnoses of ill-appearing neonates that do not respond to treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

“…11,12 Neonatal coccidioidomycosis is rare, and no cases have been described over the past 2 decades. [13][14][15][16][17][18][19][20] In an effort to better understand the disease, we reviewed recent cases in our institution and compared them with those described in the available literature.…”

mentioning

confidence: 99%

Neonatal Coccidioidomycosis

Vaughn

Tablizo

Zayed

et al. 2021

Pediatric Infectious Disease Journal

View full text Add to dashboard Cite

show abstract

“…5 In nonvertically transmitted cases, the infant likely had a primary infection by inhalation of aerosolized spores into the lungs after birth. 6,[8][9][10] The clinical presentation of infants with coccidioidomycosis has been variable, with clinical manifestations including fever, respiratory symptoms, decreased activity, decreased oral intake and meningitis. Cutaneous manifestation of neonatal coccidioidomycosis is extremely rare.…”

mentioning

confidence: 99%