Neonatal infections in Asia

Abstract

The incidence of late-onset sepsis was higher in Asia than in resource-rich countries, but the organisms isolated and mortality were similar. Over half of all Gram-negative bacilli were antibiotic resistant.

Group B streptococcal disease in infants aged younger than 3 months: systematic review and meta-analysis

“…Al-Zwaini et al 61 Tiskumara et al 62 El-Said et al 63 Ben Hamida et al 64 Subtotal (I 2 =65·6%, p=0·033)…”

“…Western Pacific Angstetra et al 65 Daley et al 66 May et al 67 Tiskumara et al 62 Tiskumara et al 62 Kim et al 68 Niduvaje et al 69 Subtotal (I 2 =54·7%, p=0·039)…”

Bacterial Isolates and its Antibiotic Susceptibility Pattern in NICU

“…Specimens from infants in the first 24 hours of life are also seriously under-represented, especially those from low birth-weight babies and babies born outside health facilities. 3,17,18 Intrapartum antibiotic prophylaxis against S. agalactiae has also led to a substantial change in the bacteria responsible for early onset neonatal sepsis; gramnegative bacilli and Staphylococcus spp. predominate in countries implementing these programs.…”

Brief communication (Original). Trends in neonatal sepsis in a neonatal intensive care unit in Thailand before and after construction of a new facility

“…Rates and causative pathogens of neonatal sepsis can vary within the same unit, among units, and across countries [11,12,16,17]. The rates of sepsis in this study are comparable to those in units in Taiwan that reported rates ranging from 3% to 4% [18,19], but lower compared with data from other countries such as the Philippines, The Netherlands, and Nigeria, where sepsis rates have been reported to range from 15.1% to 19.6% [20][21][22].…”

“…In the USA, the overall cumulative incidence of EOS is from 0.8 to 1.0 cases per 1,000 live births [9] and the rate of LOS is 36% in preterm infants (22)(23)(24)(25)(26)(27)(28) weeks gestational age/401-1500 g birth weight) [10]. Similarly, two studies of groups of neonatal intensive care unit (NICUs) in developing countries including Malaysia, Thailand, China, and India, found the rate of EOS to be from 0.62 to 0.72 cases per 1,000 live births [11,12]. However, these studies also found a rate of LOS ranging from 2.0 per 1,000 live births in Hong Kong to 22.0 per 1,000 live births in Thailand [11].…”