Neonatal Peritoneal Dialysis

Abstract

Objectives After completing this article, readers should be able to: 1. List the indications for peritoneal dialysis (PD) in neonates. 2. Delineate neonates who are poor candidates for PD. 3. Review the parameters of the PD prescription. 4. Review special nutrition considerations for neonates who are undergoing PD. 5. Review potential complications of PD in neonates.

Acute Peritoneal Dialysis in the Newborn Period: A 7-Year Single-Center Experience at Tertiary Neonatal Intensive Care Unit in Turkey

“…[10][11][12] Renal failure accounts for 7% of all deaths in NICUs. 4,13 Neonates usually develop ARF following perinatal hypoxia and shock. Congenital malformations, obstructive uropathies and bilateral renal vein thrombosis, which rarely occur in other age groups, are other causes of ARF in neonates.…”

Peritoneal Dialysis in Neonates: Six Years Single Centre Experince

“…PD is frequently required in NICU and is a basic, rational, safe, and effective renal replacement treatment method in infants with AKI and metabolic disorders. It is preferred over hemodialysis and continuous renal replacement therapy in neonates due to the technical difficulties that require vascular access in small infants (1). The decision to initiate dialysis is necessitated by electrolyte abnormalities, worsening uremia, fluid overload, persistent acid-base abnormalities, and need for increased fluid intake to achieve nutrition in a patient with oliguria (1).…”

“…Peritoneal dialysis (PD) in neonates can be effective in treating acute kidney injury (AKI) and certain metabolic disturbances such as urea cycle defects with hyperammonemia and congenital lactic acidosis (1,2). PD can be required after cardiac surgery, because even in the absence of evident signs of renal dysfunction a clinical condition of fluid retention and generalized edema is common in neonates after major cardiosurgical interventions.…”

Neonatal Acute Kidney Injury: Diagnostic and Therapeutic Challenges

“…PD facilitates the slow removal of fluids and solutes, while preventing hemodynamic instability. PD is technically a simple treatment modality, which can be continuously performed in neonates, hospitalized at neonatal intensive care units (NICUs) [40] . PD is generally performed after a failed conservative treatment.…”