Neonatal scrotal wall necrotizing fasciitis (Fournier gangrene): a case report

Zgraj, Oskar; Paran, Sri; O’Sullivan, Maureen; Quinn, Feargal

doi:10.1186/1752-1947-5-576

Cited by 9 publications

(8 citation statements)

References 8 publications

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“…Fournier’s gangrene, an infective necrotizing fasciitis of the perineal region, was first described by French venerologist Alfred Fournier ( 1 , 2 ) in 1883. This aggressive and life threatening disease is uncommon in children and very rare in neonates and has a mortality rate of near 50% in this age group ( 3 , 4 ). Prematurity, diaper rash, poor hygiene, trauma, anorectal diseases, urethral catheterization, circumcision, insect bite, strangulated hernia, omphalitis, systemic infections, immunocompromised status and hematologic malignancies are some predisposing factors in children ( 1 , 4 , 5 ).…”

Section: Introductionmentioning

confidence: 99%

Fournier’s Gangrene in a Neonate With Acute Myeloid Leukemia: A Case Report

et al. 2016

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Introduction:Fournier’s gangrene is an infective necrotizing fasciitis of external genital and perineal region. Hematologic malignancies and immunocompromised status are predisposing factors. Simultaneous occurrence of Fournier’s gangrene and congenital leukemia in neonates is extremely rare.Case Presentation:We present a case of Fournier’s gangrene in a 4-day-old female infant with a necrotic lesion in perineum and no history of trauma or other predisposing condition. Focusing on high blast percentage in blood cell count she was affected by acute myeloid leukemia (M4 type). Pseudomonas aeruginosa was isolated from the blood and wound culture. She was treated with broad spectrum antibiotics and supportive care. The parents refused chemotherapy and the patient was discharged from hospital. Bleeding and DIC was the cause of death in a local hospital few days later.Conclusions:High index of suspicion is essential for diagnosis and appropriate treatment. Congenital leukemia should be considered in the differential diagnosis of a newborn with clinical features of sepsis and necrotizing fasciitis.

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Section: Introductionmentioning

confidence: 99%

Fournier’s Gangrene in a Neonate With Acute Myeloid Leukemia: A Case Report

et al. 2016

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“…According to various authors, mortality ranged from 3% to 45% due to severe sepsis, coagulopathy and renal failure[ 1 , 17 , 20 , 21 ]. Necrotizing fasciitis in neonates is associated with a nearly 50% mortality rate[ 10 ]. The prognosis of this disease is influenced by age, the presence of infectious agents, extent of the disease, and underlying medical conditions.…”

Section: Discussionmentioning

confidence: 99%

“…Despite being named Fournier (Jean-Alfred Fournier) after he published a series of five cases, the condition was first described as an idiopathic, rapidly progressive necrotic process of the soft tissues leading to genital organ gangrene in 1764 by a physician named Baurienne[ 5 ]. Fournier gangrene in children is rare, with an annual incidence of 0.8 per million patients, and little is known about the disease in this age group[ 2 , 4 - 10 ]. A review of the literature revealed only 56 pediatric cases, with 66% of those involving infants under the age of 3 mo[ 5 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Fournier gangrene in an infant, complicated with severe sepsis and liver dysfunction: A case report

Bakalli,

Heta,

Kola

et al. 2023

World J Clin Cases

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Rehabilitation of lower limb amputation in developing countries is quite challenging. Though there are basic to highly advanced prostheses available in India, the set-up is still facing difficulties in developing countries. Prosthetic management is difficult due to lack of availability of prostheses and reduced affordability among low income populations. In this review we highlighted the lower limb amputation and prosthetic rehabilitation status in India. Currently, India is advancing well in the rehabilitation field, but further studies are required to provide more evidence and recommendation.

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“…The age of onset varies between 30 and 60 years old [1]. However somes cases have been reported in children [8].…”

Section: Discussionmentioning

confidence: 99%

Fournier’s Gangrene in a Patient with a Bladder Cancer: A Lethal Association

Kaboré¹,

Kaboré²,

Kabre³

et al. 2021

IJCU

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Fournier's gangrene is a rare and life-threatening condition. It mainly affects men. Progress in resuscitation has reduced its mortality rate but it remains very high. We report a case of Fournier's gangrene in a 30-year-old male patient admitted to our emergency room for 24 hours history of a bilateral painful scrotal swelling with fever. In his prior history the patient was followed for squamous cell carcinoma of the bladder with ureteral meatus invasion and renal failure. On physical examination we noted a severe sepsis: temperature was 39.2° Celsius, pulse rate was 115 beats per minute, respiratory rate was 26 breaths per minute, blood pressure was 80/60 mmHg. We noted a bilateral and painful scrotal swelling with snow crepitation in burses and edema of the penile. The Fournier's Gangrene Severity Index was 17. After hydroelectrolytic resuscitation, a surgical debridement was performed. An antibiotherapy with third-generation cephalosporin and imidazole was administered. The patient died of septic shock 24 hours after the debridement. Through this clinical case we showed that Fournier's gangrene has a severe prognosis. FGSI is an interesting predictive score in the evaluation of the patient's vital prognosis. The association between FG and bladder tumor worsens the patient's vital prognosis. Bladder cancer and Fournier's gangrene realize a lethal association.

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Neonatal scrotal wall necrotizing fasciitis (Fournier gangrene): a case report

Cited by 9 publications

References 8 publications

Fournier’s Gangrene in a Neonate With Acute Myeloid Leukemia: A Case Report

Fournier’s Gangrene in a Neonate With Acute Myeloid Leukemia: A Case Report

Fournier gangrene in an infant, complicated with severe sepsis and liver dysfunction: A case report

Fournier’s Gangrene in a Patient with a Bladder Cancer: A Lethal Association

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