Neonatal Skin and Chlorhexidine: A Burning Experience

Kutsch, Jennifer; Ottinger, Daniele

doi:10.1891/0730-0832.33.1.19

Cited by 23 publications

(21 citation statements)

References 8 publications

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“…It has four chlorophenyl rings and two bisguanide groups connected by a central hexamethylene bridge [1]. cases, thereby predisposing them to sepsis, excessive water loss, hypothermia and renal failure [3]. But we have to be more cautious when using clorhexidine on skin, mucous membranes or other external areas.…”

Section: Topical Antiseptics Chlorhexidinementioning

confidence: 99%

Undesirable Effects of Some Topical Antiseptics Chemical, pharmacological and dermatological aspects

Tatu¹,

Ardeleanu²,

Elisei³

et al. 2019

Rev. Chim.

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Topical antiseptics are a diverse group of agents that are widely used in medicine for the antimicrobial properties. Despite their long history and broad application, caution must be exercised in their use, especially in the pediatric age group, as various cutaneous reactions ranging from hypersensitivity to urticarial to skin necrosis have been reported. The use of topical antiseptics in pediatrics has also been associated with systemic reactions, which depend on the antiseptic in question. Antiseptics such as chlorhexidine, povidon iodine, methylene blue, gentian violet, silver nitrate, boric acid, Castellani solution, alcohol and chloramines have been reviewed. It is essential that physicians bear in mind the possible adverse effects that may follow topical antiseptic use, as this facilitates prevention and also timely intervention if, and when, they occur.

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Section: Topical Antiseptics Chlorhexidinementioning

confidence: 99%

Undesirable Effects of Some Topical Antiseptics Chemical, pharmacological and dermatological aspects

Tatu¹,

Ardeleanu²,

Elisei³

et al. 2019

Rev. Chim.

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“…Povidonjod interferiert mit der Synthese von Schilddrüsenhormonen und ist daher kontraindiziert [111,112]. Auch Chlorhexidin (CHX) in wäss-riger Lösung (CHX-Gluconat 2 %) kann bei sehr unreifen Frühgeborenen schwere Hautreaktionen verursachen [113,114]. Verbände, die lokal CHX an der Eintrittsstelle eines PICC freisetzen, können bei Früh-und Neugeborenen schwerwiegende lokale Unverträglichkeiten auslösen [115,116].…”

Section: Hautantisepsis Vor Invasiven Maßnahmenunclassified

Prävention von Gefäßkatheter-assoziierten Infektionen bei Früh- und Neugeborenen

2018

Bundesgesundheitsbl

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Kategorie IADiese Empfehlung basiert auf gut konzipierten systematischen Reviews oder einzelnen hochwertigen randomisierten kontrollierten Studien. Kategorie IBDiese Empfehlung basiert auf klinischen oder hochwertigen epidemiologischen Studien und strengen, plausiblen und nachvollziehbaren theoretischen Ableitungen.Kategorie II Diese Empfehlung basiert auf hinweisenden Studien/Untersuchungen und strengen, plausiblen und nachvollziehbaren theoretischen Ableitungen. Kategorie IIIMaßnahmen, über deren Wirksamkeit nur unzureichende oder widersprüchliche Hinweise vorliegen, deshalb ist eine Empfehlung nicht möglich. Kategorie IVAnforderungen, Maßnahmen und Verfahrensweisen, die durch allgemein geltende Rechtsvorschriften zu beachten sind.

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“…106 Bacterial colonization and infection management If there are signs of infection, it will be necessary to apply impregnated dressings with topical antiseptics (silver, polyhexamethylbiguanide) that are not contraindicated in neonates. 24,107,108 When using silver, some authors recommend that an analytical control should be done within 2 weeks of being prescribed, followed by a resting period. 109 The application of iodinated antiseptics is not recommended, which may favor the onset of hypothyroidism.…”

mentioning

confidence: 99%

Neonatal pressure ulcers: prevention and treatment

García-Molina¹,

Alfaro-López²,

García-Rodríguez³

et al. 2017

RRN

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Health professionals should be prepared to respond to the needs of hospitalized neonates. The health team must consider multiple situations, where the neonate is at risk of having an adverse effect. One of the main interventions that health professionals must practice when interacting with hospitalized newborns is skin care. Neonates often suffer from diaper rash or intravenous drugs extravasation. Recently, hospitalized neonates and especially those in an unstable clinical situation are also at a risk of developing pressure ulcers. The presence of a pressure ulcer in a neonate can lead to serious problems to survival (eg, sepsis, clinical instability). This is the reason why, with this literature review, we attempt to answer questions from health professionals caring for neonates about the prevention and treatment of pressure ulcers.

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Neonatal Skin and Chlorhexidine: A Burning Experience

Abstract: CHG does have a strong association with causing skin burns in the ELBW population; however, wiping the solution off of the skin seems to reduce injury.

Cited by 23 publications

References 8 publications

Undesirable Effects of Some Topical Antiseptics Chemical, pharmacological and dermatological aspects

Undesirable Effects of Some Topical Antiseptics Chemical, pharmacological and dermatological aspects

Prävention von Gefäßkatheter-assoziierten Infektionen bei Früh- und Neugeborenen

Neonatal pressure ulcers: prevention and treatment

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