Neonatal vitamin D status at birth at latitude 32°72′: evidence of deficiency

Abstract

Objective: With vitamin D deficiency as a serious public health problem, vitamin D status at birth was measured in neonates at latitude 32172 0 (southeastern United States).Study Design: In umbilical cord blood, vitamin D status, demonstrated by circulating 25-hydroxyvitamin D, was measured and related to race and season of birth.Result: The mean±standard deviation of 25-hydroxyvitamin D in 100 cord blood samples was 13.5±8.3 ng/ml for the cohort. African-American infants, with a mean±standard deviation of 10.5±6.0 ng/ml, demonstrated significantly lower vitamin D status than Caucasian infants, with a mean±standard deviation of 19.5±9.6 ng/ml (P<0.0001). By season, the mean 25-hydroxyvitamin D level at birth in NovemberMarch compared to April-October was 11.3 ng/ml lower in Caucasian infants (from 29.0 to 17.7 ng/ml) and 3 ng/ml lower in African-American infants (from 13.1 to 10.1 ng/ml).

Prenatal factors associated with the neonatal line thickness in human deciduous incisors

“…Seasonality of maternal and (in conseqence) infant vitamin D status with significant decrease observed in winter was analysed by many authors (e.g. Basile et al, 2007;Bowyer et al, 2009;Greer, 2008;Merewood et al, 2010). Such a relationship seems to be confirmed by the research of Zeghoud et al (1997) conducted on 80 full-term neonates born from April to July 1991 in Compiègne (France).…”

Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents

“…73,74,[126][127][128][129] Infants who are exclusively breastfed but who do not receive supplemental vitamin D or adequate sunlight exposure are at increased risk of developing vitamin D deficiency and/or rickets. 7,[10][11][12]14,18,81,130 Infants with darker pigmentation are at greater risk of vitamin D deficiency, 131 a fact explained by the greater risk of deficiency at birth 132 and the decreased vitamin D content in milk from women who themselves are deficient. 127 A …”

Maternal and infant vitamin D status during the first 9 months of infant life—a cohort study

“…1,2 Pregnant and lactating women and their newborn infants are at a high risk of vitamin D deficiency. [3][4][5][6][7][8][9][10][11][12] Vitamin D is involved in skeletal homeostasis during pregnancy. 13,14 Severe vitamin D deficiency with profound hypocalcemia may lead to seizures in neonates, and has also been associated with low birth weight, prenatal death, preeclampsia and an increased risk of primary cesarean section.…”