Neoplasms of the Testis

Emerson, Robert E.; Ulbright, Thomas M.

doi:10.1016/b978-0-323-54941-7.00013-x

Cited by 2 publications

(2 citation statements)

References 945 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to the AJCC classification, seminomas are subdivided into T1a for those <3 cm in diameter T1a, tumors ≥3 cm in diameter into T1b. 23 In a study by Farooq et al, findings of seminoma size (≥3 cm or <3 cm) associated with the metastatic condition at the time of diagnosis support the current pathological T1a and T1b stages for seminoma, consistent with previous findings. 18 In our patient series, tumor size was ≥3 cm in 39/56 (70%) patients with pure seminomas and <3 cm in 14/56 (25%) patients.…”

Section: Discussionsupporting

confidence: 78%

“…10 Regardless of vascular invasion, epididymal invasion or hilar soft tissue invasion leads the disease to the T2 stage. 23 In a study by Yılmaz et al, hilar soft tissue invasion was more common in patients in advanced clinical stages (48% in stages 2 and 3, 17% in stage 1) in NSGCTs. Hilar soft tissue invasion has been reported to be correlated with vascular invasion and rete testis invasion.…”

Section: Discussionmentioning

confidence: 92%

See 1 more Smart Citation

Histopathological Analysis in Testicular Tumors: 10 Years of Experience

Kılınç,

Tas Ayçiçek,

Esen

2023

Int J Surg Pathol

View full text Add to dashboard Cite

Introduction. This study aims to review the morphological and immunohistochemical features of testicular tumors and compare them with prognostic parameters. Methods. Testicular tumors diagnosed between January 2011 and September 2021 were reviewed. Patient age, tumor subtype, size, spread, lateralization, number of foci, and immunohistochemical results were recorded. Results. A total of 121 tumors were detected, of which 108 (89%) were germ cell tumors (GCTs). Of the germ cell tumors, 70 (65%) were found to be pure type, and 38 (35%) were mixed germ cell tumors. The ratio of pure seminoma among GCTs was 56/108 (52%). Lymphatic/vascular invasion (LVI) was detected in 48/121 (40%), rete testis invasion in 32/121 (26%), hilar soft tissue invasion in 10/121 (8%), epididymal invasion in 5/121 (4%), and spermatic cord invasion in 5/121 (4%) patients. Lymphatic/vascular invasion was observed in 6 (22%) of 27 germ cell tumors smaller than 3 cm in size, and rete testis invasion was observed in 2 (7%), while in 40 (55%) of the 73 germ cell tumors of 3 cm and above, lymphatic/vascular invasion was seen, and 26 (36%) of them had rete testis invasion. Immunohistochemical results contributed significantly to the determination of tumor components and rates, especially in mixed germ cell tumors. Conclusion. Most of the tumors were germ cell tumors, and the majority were seminomas. Lymphatic/vascular invasion and rete testis invasion rates increase as the tumor diameter increases, which is more evident when the 3 cm cut-off value is taken into account ( P < 0.005).

show abstract

Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 92%