Neopterin, procalcitonin, total sialic acid, paraoxonase-1 and selected haematological indices in calves with aspiration pneumonia

Akyüz, Enes; Merhan, Oğuz; Aydin, Uğur; SEZER, Mert; Kuru, Mushap; Karakurt, Emin; YILDIZ, Uğur; Bozukluhan, Kadir; Batı, Yusuf Umut; Yıldız, Ayfer; Gökçe, Gürbüz

doi:10.2754/avb202291020115

Cited by 12 publications

(10 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This result agrees with previous findings showing low PON-1 activity in calves with aspiration pneumonia. 15 Our data indicate that PON-1 was lower using a ≥3 cm cutoff than ≥1 cm. This result appeared most evident among the variables analyzed in our study.…”

Section: Categorizationsmentioning

confidence: 52%

“…13 Paraoxonase-1 is a negative acute phase protein, 14 and the lower activity during inflammation might result from reduced hepatic synthesis, displacement from high-density lipoproteins, and increased peripheral consumption to counteract free radicals. [13][14][15] We believe that describing the presence and the degree of abnormalities of pulmonary gas exchange, acid-base, and metabolic disarrangements that characterize the most commonly used diagnostic methods for the diagnosis of BP in calves can help clarify the ability of these tools to diagnose the physiological state of the calves and, thus the severity of the ongoing disease. Furthermore, we believe that this study could provide new insights into systemic changes during BP that should contribute to a better understanding and knowledge of the disease in preweaned dairy calves.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Blood gases, acid‐base, and metabolic alterations in calves with bronchopneumonia diagnosed via clinical signs and thoracic ultrasonography: A cross‐sectional study

Boccardo,

Ferrulli,

Sala

et al. 2024

Veterinary Internal Medicne

View full text Add to dashboard Cite

BackgroundBronchopneumonia (BP) in calves potentially causes systemic changes.ObjectivesTo describe metabolic, arterial blood gas, and acid‐base disorders in calves with BP diagnosed by thoracic ultrasound (TUS), Wisconsin score (WISC), and combinations of WISC and TUS.AnimalsTwo hundred thirty‐one dairy preweaned dairy calves from 13 dairy farms.MethodsCross‐sectional study. Each calf sequentially underwent arterial blood gas evaluation, WISC score, venous sampling, and TUS. Calves were grouped based on a single diagnostic method and combination of WISC and 2 TUS cutoffs (≥1 cm; ≥3 cm) as healthy, upper respiratory tract infection, subclinical BP, and clinical BP.ResultsOxygenation and acid‐base variables were unaffected. Glucose concentration in TUS‐affected calves was significantly lower (P < .001) than in healthy calves (median ≥TUS1cm = 5.2 mmol/L 25%‐75% interquartile range [IQR] 4.5‐6.1, <TUS1cm = 5.9 mmol/L IQR 5.5‐6.6; ≥TUS3cm = 5.1 mmol/L IQR 4.4‐6.2, <TUS3cm = 5.8 mmol/L IQR 5.3‐6.4). Paraoxonase‐1 was significantly lower (P < .001) in TUS‐affected calves (≥TUS1cm = 64.1 U/mL IQR 40.8‐78, <TUS1cm = 77.3 U/mL IQR 61.9‐96.5; ≥TUS3cm = 59.2 U/mL IQR 37.7‐72.4, <TUS3cm = 72.9 U/mL IQR 53.4‐95.5). None of the variables highlighted clear distinctions in WISC‐detected clinical and subclinical BP calves based on the combination of WISC and TUS.Conclusions and Clinical ImportanceClinical signs indicate minor systemic disorders compared to TUS. The abnormalities detected by ultrasonographic examination were moderate and did not deviate from normal reference ranges.

show abstract

Section: Categorizationsmentioning

confidence: 52%

Section: Introductionmentioning

confidence: 99%

Blood gases, acid‐base, and metabolic alterations in calves with bronchopneumonia diagnosed via clinical signs and thoracic ultrasonography: A cross‐sectional study

Boccardo,

Ferrulli,

Sala

et al. 2024

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…Leukocytosis is observed as a result of defense mechanisms in respiratory system diseases and bacterial infections (Akyüz & Gökce, 2021;Akyüz et al, 2022). In the study we presented, respiratory system infection caused by P. multocida was formed.…”

Section: Discussionmentioning

confidence: 87%

Comparison of enrofloxacin and tulatromycin treatments in sheep with Pasteuralla multicida pneumonia

Akyüz

Erkiliç

Çoşkun

et al. 2022

Journal of Advances in VetBio Science and Techniques

Self Cite

View full text Add to dashboard Cite

In this study, it was aimed to compare the treatments of enrofloxacin and tulatromycin in sheep with pneumonia caused by Pasteuralla multicida. A total of 45 female Tuj sheep between the ages of 2-6 were used in the study. Group 1 enrofloxacin administered 15 sheep, group 2 tulatromycin administered 15 sheep, and 15 healthy sheep of the same age group and characteristics formed the control group. Bronchoalveolar lavage fluid samples were obtained from sheep with clinical signs (cough, purulent, serous, mucopurulent nasal discharge) of respiratory system disease. After the microbiological examination of the samples taken, those positive for Pasteuralla multicida were included in the study. Blood samples (10 mL) from the Vena jugularis were collected in serum tubes with K2EDTA and gel from the sick animals before and after the treatment as well as once from the control group. In our study, rectal temperature, respirations per minute and pulse rates before treatment were found to be statistically significantly higher in patient groups compared to the control group (P<0.001). Total leukocyte count was found to be higher in the patient groups before treatment compared to the control group (P=0.010). Among the biochemical parameters, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, urea and creatine kinase levels were found to be statistically significantly higher in the patient groups compared to the control group before treatment (P<0.05). Clinical improvement was observed from the 3th day in group 2 and from the 5th day in group 1. As a result, administration of a single dose of tulatromycin resulted in earlier clinical improvement than administration of enrofloxacin for one week. At the same time, it was concluded that tulatromycin is more beneficial and practical in terms of a single application.

show abstract

“…9 In the acute phase of a reaction, sialic acid is considered a biomarker . 18 The negative charge on renal basement membrane also controlled by sialic acid, so sialic acid consider as one of main regulator of membrane permeability. 19,20 Approximately 50% of the free sialic acid in serum is provided by acute phase proteins, while the bound form is cleared by the renal system along with creatinine, resulting in minor reabsorption and maximum filtration at the glomerulus.…”

Section: Discussionmentioning

confidence: 99%

Estimation of Serum Sialic Acid in the Patients of Type-2 Diabetes Mellitus

Chandio¹,

Shafi²,

Asif³

et al. 2022

PJMHS

View full text Add to dashboard Cite

Background: Diabetes Mellitus is one of the leading cause of morbidity & mortality all over the world. The poor glycemic control in the patients of type-II diabetes mellitus can lead the development of complications which cause the morbidity in the life of diabetic population. The aim of this study was to estimate the serum sialic acid in the patients of type- II diabetes for early prediction of diabetic complications. Methodology: This case comparative study was conducted at the Diabetes Clinic of LUMHS Jamshoro with the collaboration of the Department of Biochemistry at LUMHS. A total of 84 diagnosed cases of type-II Diabetes Mellitus were included in this study. In group A, 40 diabetes mellitus cases were diagnosed with a history of diabetes less than five years, while in group B 44 had histories of diabetes over ten years. Spectrophotometers were used to measure serum sialic acid levels using Ehrlich's reagent. SPSS version 22 was used for data analysis with independent student t tests applied. Results: The mean serum sialic acid level of group A was 56.42 ± 5.67 mg/dl, while serum sialic acid level of group B was 69.88 ± 7.34 mg/dl. There was significant (p<0.05) increased level of serum sialic acid in the type-II diabetic patients of group B, which indicate there is more chance to development of micro vascular complications in type-II diabetic patients with prolong duration for their diseases period. Conclusion: Estimation of serum sialic acid in the patients of type-II diabetes mellitus is one of the early predictive marker for the complications of diabetes mellitus. Keywords: Type-II Diabetes Mellitus, Serum Sialic Acid, Estimation, HBA1C

show abstract

Neopterin, procalcitonin, total sialic acid, paraoxonase-1 and selected haematological indices in calves with aspiration pneumonia

Cited by 12 publications

References 25 publications

Blood gases, acid‐base, and metabolic alterations in calves with bronchopneumonia diagnosed via clinical signs and thoracic ultrasonography: A cross‐sectional study

Blood gases, acid‐base, and metabolic alterations in calves with bronchopneumonia diagnosed via clinical signs and thoracic ultrasonography: A cross‐sectional study

Comparison of enrofloxacin and tulatromycin treatments in sheep with Pasteuralla multicida pneumonia

Estimation of Serum Sialic Acid in the Patients of Type-2 Diabetes Mellitus

Contact Info

Product

Resources

About