Neovascular pattern in wound healing after zinc oxide and Curcuma longa rhizome extract dressing application

Faiga, Nilna Naila; Rachmadi, Priyawan; Meizarini, Asti

doi:10.4103/ccd.ccd_435_18

Cited by 5 publications

(1 citation statement)

References 20 publications

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“…The addition of C. longa rhizome extract showed added value in the wound healing process in term of the number of neovascular. 36 Nevertheless, the wound sites examined were in the dorsal part of rats which had different environment and circumstances from oral sites. In the present study, wounds were created in the gingival tissue surrounding by oral environment.…”

Section: Discussionmentioning

confidence: 99%

Histological Examination of Lemongrass Resorbable Dressing on Gingival Healing after Gingivectomy in Rats

Amaliya

Budhirahardjo²,

Hendiani

2022

Eur J Dent

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Objectives The present work aimed to evaluate the effect of lemongrass extract incorporated in a resorbable periodontal dressing on gingival wound healing microscopically, following gingivectomy in rats. Materials and Methods Thirty healthy adult male Sprague–Dawley rats were used in this study. Gingivectomy was performed on anterior area of lower jaw in the labial surface of central incisive and, subsequently, wound areas were covered with povidone iodine gel (group P, positive control, n = 10), lemongrass resorbable dressing (group L, n = 10), and a cellulose-based dressing containing myrrh (group M, positive control, n = 10). Histological changes were monitored in days 4, 7, and 14 postsurgery to evaluate fibroblast and collagen deposition as repair stage of healing process. Statistycal Analysis One-way analysis of variance (ANOVA) followed by Tukey's post hoc for multiple comparisons were employed to measure differences between pairs of means, p-value of 0.05 was considered statistically significant. Results We observed significant difference repair parameters of the healing process between surgical sites treated with lemongrass periodontal dressing and control groups. Wounds treated with lemongrass dressing had greater fibroblast compared with control groups in 4 and 7 days after surgery (p ≤ 0.05). Conclusion The results suggest positive potential therapeutic effects for this new formulation of periodontal dressing on acceleration of surgical wound healing that lead to improvement of periodontal treatment consequences following gingivectomy.

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Section: Discussionmentioning

confidence: 99%

Histological Examination of Lemongrass Resorbable Dressing on Gingival Healing after Gingivectomy in Rats

Amaliya

Budhirahardjo²,

Hendiani

2022

Eur J Dent

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Eugenol Loaded Ag-Ti-Co Nanocomposite as a Promising Antimicrobial and Antioxidative Agent

et al. 2023

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Comparison of Rate of Canine Retraction and Secondary Outcomes Associated With Conventional Fixed Orthodontic Treatment and Minimally Invasive Techniques (MOPs): A Randomized Control Trial

Parihar

Verma

Chaturvedi

et al. 2020

J Indian Orthod Soc

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Introduction: The objective of the study was to assess the rate of canine retraction and secondary outcomes associated with conventional fixed orthodontic treatment (CFO) and CFO with micro-osteoperforation (CFO + MOP), that is, anchorage loss, root resorption, vitality of tooth, pain and discomfort level during the procedure. Methods: A total of 16 patients with Class II Division 1 malocclusion who required upper first premolar extraction with lower non-extraction/single incisor extraction were divided into the test group (MOP) and positive control group (CFO + MOP) for a split-mouth study. Both maxillary canines were retracted with nickel–titanium (NiTi) closed coil springs. Patients were reviewed after 24 hours, 7 days, 28 days, and 4, 8, and 16 weeks to assess the rate of tooth movement, anchorage loss, root resorption, vitality of tooth, pain and discomfort level. Results: There was a statistically significant difference in the rate of tooth movement between the CFO and CFO + MOP groups after the first 4 weeks ( P-value = .026), whereas no statistically significant difference was observed at 8, 12, and 16 weeks ( P-value = .33, .99, and .08, respectively). In the CFO group, there was no statistically significant difference in tooth movement between different time intervals ( P-value > .05). There was no significant difference in root resorption between the groups. The pain level was higher in the MOP group in the first 24 hours ( P-value < .05) after the procedure. Later on, the difference in pain level between the groups was not significant ( P-value > .05). The vitality of retracted canines in both groups was healthy. Conclusion: The study recommends that the CFO + MOP procedure has substantial potential to be used as an adjunct to the routine mechanotherapy for faster tooth movement, as it may reduce the treatment time by half in the first 4 weeks after the MOP procedure. There are no potential differences in anchorage loss, tipping, vitality, and apical and lateral root resorption between the CFO and CFO + MOP groups. This trial was registered at Clinical Trial Registry, India.

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Neovascular pattern in wound healing after zinc oxide and Curcuma longa rhizome extract dressing application

Cited by 5 publications

References 20 publications

Histological Examination of Lemongrass Resorbable Dressing on Gingival Healing after Gingivectomy in Rats

Histological Examination of Lemongrass Resorbable Dressing on Gingival Healing after Gingivectomy in Rats

Eugenol Loaded Ag-Ti-Co Nanocomposite as a Promising Antimicrobial and Antioxidative Agent

Comparison of Rate of Canine Retraction and Secondary Outcomes Associated With Conventional Fixed Orthodontic Treatment and Minimally Invasive Techniques (MOPs): A Randomized Control Trial

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