2020
DOI: 10.1016/j.urology.2020.05.063
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Nephrolithiasis and Elevated Urinary Ammonium: A Matched Comparative Study

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Cited by 8 publications
(8 citation statements)
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“…To account for dietary acid ash content, we examined the difference of urinary ammonium to urinary sulfate (NH 4 -SO 4 ). 23 A two-sided P-value of <0.05 was considered statistically significant. All analyses were performed using SPSS v25.…”
Section: Discussionmentioning
confidence: 99%
“…To account for dietary acid ash content, we examined the difference of urinary ammonium to urinary sulfate (NH 4 -SO 4 ). 23 A two-sided P-value of <0.05 was considered statistically significant. All analyses were performed using SPSS v25.…”
Section: Discussionmentioning
confidence: 99%
“…In patients with nephrolithiasis, high urinary ammonium levels could signal the presence of urease producing bacteria and struvite stones or a high protein diet. 10 In summary, the enzymatic plasma ammonium assay used here reliably quantified urinary ammonium concentration after specimen dilution. The modified assay we used had broad analytical measurement range (2.92 -45.0 mmol/L in undiluted urine), which is expected to quantify ammonium in most patient samples without additional dilution.…”
Section: Discussionmentioning
confidence: 86%
“…Quantification of urinary ammonium levels is also helpful in evaluating patients with normal anion gap metabolic acidosis to determine if the etiology is due to diarrhea or renal tubular acidosis (RTA) (8,9). Urinary ammonium levels can also aid in the management of patients with nephrolithiasis by providing an assessment of the daily acid load, provided kidney function is normal and there is no co-existing RTA, or signaling the presence of struvite stones (10).…”
Section: Introductionmentioning
confidence: 99%
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“…If the gastrointestinal alkali loss is also associated with potassium depletion and volume depletion with low sodium delivery to the distal nephron, urine pH can rise to 6 or slightly higher, represented by the slanted dashed line in the lower right quadrant of the graph. This situation can be confused with dRTA, but the high NH 4 – SO 4 value clearly rules out dRTA [33,34 ▪ ].…”
Section: Clinical Applicationmentioning
confidence: 99%