Nephron Sparing Surgery in Incidental Versus Suspected Renal Cell Carcinoma

Licht, Mark R.; Novick, Andrew C.; Goormastic, Marlene

doi:10.1016/s0022-5347(17)32810-0

Cited by 240 publications

(82 citation statements)

References 13 publications

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“…[8][9][10][11][12][13] In the present series, by the end of the study period, in the incidental group there was only one case of progression, while among the 56 patients in the symptomatic group, 5 showed progression and 10 died. The probability of disease-free survival after 5 and 9 years was respectively, 98% and 98% for the incidental group and 62% and 53% for the symptomatic group (p < 0.001).…”

Section: Publishing Informationcontrasting

confidence: 40%

“…4 The most common symptoms are hematuria, low back pain and palpable mass, and these events occur in isolation in 35-59%, 34-41% and 30-45% of the cases, respectively. [5][6][7] The 5-year survival rate for symptomatic tumors is 30-83% while for incidental tumors it is 83-95% [8][9][10][11][12][13] and, according to tumor staging, the rate is 91% for PT1, 74% for PT2, 67% for PT3 and 32% for PT4. 14 Metastatic disease is seen in 25-40% of the cases at diagnosis, 15,16 with a 5-year survival rate of 13%.…”

Section: Introductionmentioning

confidence: 99%

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Incidental and symptomatic renal tumors: impact on patient survival

et al. 2002

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CONTEXT: Renal cell carcinoma is the third most frequent genitourinary neoplasia, and there is currently an increase in the incidental diagnosis of tumors confined to the kidneys. OBJECTIVE: To study the survival of patients with incidental and symptomatic renal tumors who have undergone nephrectomy.DESIGN: Retrospective. SETTING: Hospital Sírio Libanês and Beneficência Portuguesa de São Paulo. PARTICIPANTS: 115 patients with diagnosis of renal cell carcinoma, operated on by the same group of surgeons and evaluated by a single pathologist. MAIN MEASUREMENTS: Sex, age and diagnosis method, analyzed in two groups, according to the tumor diagnosis: Group 1 with incidental diagnosis and Group 2 with symptomatic tumors. The anatomopathological characteristics and patient survival in both groups were evaluated. A statistical analysis was performed using the Student t, chi-squared, log rank and Kaplan-Meyer tests. RESULTS: Among the studied patients, 59(51%) had an incidental diagnosis, with 78% diagnosed by ultrasonography, 20% by computerized tomography scan and 2% during surgeries; 56 patients (49%) were symptomatic. Tumor locations were equally distributed between the two kidneys, and the surgery was conservative for 24% of the incidental and 9% of the symptomatic group. In the incidental group only one patient had tumor progression and there was no death, while in the symptomatic group there were 5 progressions and 10 deaths. The 5-year specific cancer-free survival was 100% in the incidental and 80% in the symptomatic group (p = 0.001) while the disease-free rate was 98% in the incidental and 62% in the symptomatic group (p < 0001). CONCLUSION: Incidental renal tumor diagnosis offers better prognosis, providing longer disease-free survival.

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Section: Publishing Informationcontrasting

confidence: 40%

Section: Introductionmentioning

confidence: 99%

Incidental and symptomatic renal tumors: impact on patient survival

et al. 2002

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“…The major disadvantage of Nephron sparing surgery for RCC is the risk of postoperative local tumor recurrence in the kidney that was operated on, which has been observed in 4% to 6% of patients 6,7 .Other disadvantages are hemorrhage, urinary leakage, fistula formation, renal artery thrombosis.…”

Section: Discussionmentioning

confidence: 99%

Concurrent renal cell carcinoma in one kidney and complete stag horn stone in the opposite kidney- a case report

Uddin¹,

Kabir²,

Khan³

et al. 2017

KYAMC j.

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The simultaneous occurrence of renal cell carcinoma (RCC) in one kidney & stag horn calculus in another kidney is rare combination. We report a 60-year-old man with concurrent large RCC in one kidney & a complete stag horn stone in the opposite kidney. He was admitted to the hospital because of occasional right loin pain and recently diagnosed hypertension leading to the diagnosis of right renal stone and incidental left renal solid mass in ultrasound scan. Contrast enhanced CT scan revealed 8cm x 6 cm irregular contrast enhanced solid mass(RCC)in the left kidney with extension to perinephric fat and 2.5 cm x 1.5 cm stag horn stone with two small caliceal calculi in the right kidney. Open extended pyelolithtomy(Rt) followed by Laparoscopic left radical nephrectomy were performed. Priority, nature of surgery, and post operative residual renal functional status were among the important considerations in this particular case.KYAMC Journal Vol. 4, No.-2, Jan 2014, Page 423-426

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“…Attention must be taken not to disrupt any lumbar vessels in the hilum when applying the clamp. Occasionally, small, superficial, completely exophytic tumors may be managed without hilar clamping (11).…”

Section: Transperitoneal Approachmentioning

confidence: 99%

Laparoscopic partial nephrectomy for cancer: techniques and outcomes

et al. 2005

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Open partial nephrectomy is the gold standard nephron-sparing treatment for small renal tumors. Technical aspects of laparoscopic partial nephrectomy have evolved considerably, and the technique is approaching established status at our institution. Over the past 4 years, the senior author has performed more than 400 laparoscopic partial nephrectomies at the Cleveland Clinic. Herein we present our current technique and review contemporary outcome data.

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Nephron Sparing Surgery in Incidental Versus Suspected Renal Cell Carcinoma

Cited by 240 publications

References 13 publications

Incidental and symptomatic renal tumors: impact on patient survival

Incidental and symptomatic renal tumors: impact on patient survival

Concurrent renal cell carcinoma in one kidney and complete stag horn stone in the opposite kidney- a case report

Laparoscopic partial nephrectomy for cancer: techniques and outcomes

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