2022
DOI: 10.1002/jor.25280
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Nerve decompression surgery suppresses TNF‐ɑ expression and T cell infiltration in a rat sciatic nerve chronic constriction injury model

Abstract: Decompression surgery (DS) is a standard treatment for chronic nerve compression injuries; however, the mechanisms underlying its effects remain unclear. Here, we investigated the effects of DS on messenger RNA (mRNA) expression of tumor necrosis factor‐α (TNF‐α) and T cell recruitment in a rat sciatic nerve (SN) chronic constriction injury (CCI) model. Male Wistar rats were subjected to CCI to establish a model of SN injury (CCI group). DS, in which all ligatures were removed, was performed 3 days after CCI s… Show more

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Cited by 4 publications
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References 49 publications
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