Neural Correlates of Repetition Priming: A Coordinate-Based Meta-Analysis of fMRI Studies

Abstract

Repetition priming is a form of implicit memory, whereby classification or identification of a stimulus is improved by prior presentation of the same stimulus. Repetition priming is accompanied with a deceased fMRI signal for primed vs. unprimed stimuli in various brain regions, often called "repetition suppression," or RS. Previous studies proposed that RS in posterior regions is associated with priming of perceptual processes, whereas RS in more anterior (prefrontal) regions is associated with priming of conceptual processes. To clarify which regions exhibit reliable RS associated with perceptual and conceptual priming, we conducted a quantitative meta-analysis using coordinate-based activation likelihood estimation. This analysis included 65 fMRI studies that (i) employed visual repetition priming during either perceptual or conceptual tasks, (ii) demonstrated behavioral priming, and (iii) reported the results from whole-brain analyses. Our results showed that repetition priming was mainly associated with RS in left inferior frontal gyrus and fusiform gyrus. Importantly, RS in these regions was found for both perceptual and conceptual tasks, and no regions show RS that was selective to one of these tasks. These results question the simple distinction between conceptual and perceptual priming, and suggest consideration of other factors such as stimulus-response bindings.

Priming Engineers to Think About Sustainability: Cognitive and Neuro-Cognitive Evidence to Support the Adoption of Green Stormwater Design

“…The priming intervention led to a reduction in activation in the ventrolateral (VLPFC) and DLPFC. These occurrences of de-activation from the municipal resolution and activation from the priming intervention take place in distinct regions of the brain, yet, are both consistent with the literature ( Henson, 2003 ; Gong et al, 2016 ; Lee et al, 2020b ). When risk decreases, decision-makers with a low risk tolerance elicit higher levels of oxygenated blood in their right lateral PFC ( Tobler et al, 2009 ).…”

“…When risk decreases, decision-makers with a low risk tolerance elicit higher levels of oxygenated blood in their right lateral PFC ( Tobler et al, 2009 ). Similarly, a reduction in activation in the PFC was previously observed when priming participants in both a learning and reasoning task ( Gong et al, 2016 ; Lee et al, 2020b ).…”

Increase in Low-Frequency Oscillations in fNIRS as Cerebral Response to Auditory Stimulation with Familiar Music

“…During the second music exposure, an increase in LFO power was only observed in the O2Hb signal for the left hemisphere in 3 out of 6 subjects, and the effect size of the increase was rather small. A repetition-related reduction in the neural hemodynamic response of the prefrontal areas has already been observed in several fMRI and fNIRS studies [ 37 , 38 , 39 ] and could explain this finding, considering that each subject listened always to the same musical piece, repeated in a loop. Our results showing an increase in LFO power with left lateralization after first music exposure and a repetition-related habituation effect strongly suggest that specific cerebral information is contained in the fNIRS signal.…”

Effect of repetition on the behavioral and neuronal responses to ambiguous Necker cube images

“…The repetition suppression in posterior regions evidenced priming of perceptual processes. The effect in more anterior (prefrontal) regions accompanied priming of conceptual processes 6 . In addition to repetition suppression, repeated stimulus presentation can also enhance brain responses relative to its first presentation, a phenomenon called repetition enhancement .…”