Neural origins of basal diencephalon in teleost fishes: Radial versus tangential migration

Wullimann, Mario F.

doi:10.1002/jmor.21237

Cited by 18 publications

(24 citation statements)

References 54 publications

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“…In mammals, all divisions comprising the mesodiencephalic dopaminergic neurons that correspond to the SNc/VTA arise exclusively from shh-expressing cells [ 124 ]. These results thus reinforce the homology of the zebrafish neurons in the PT with the mammalian SNc/VTA [ 123 , 125 ]. Additionally, the Nurr1 gene, which is mandatory for the differentiation of midbrain dopaminergic neurons in mammals, is also expressed in the zebrafish PT [ 126 ].…”

Section: Evolution Of Mesodiencephalic Dopaminergic Neuronssupporting

confidence: 77%

The Dopaminergic Control of Movement-Evolutionary Considerations

Pérez‐Fernández

Barandela

Jiménez-López

2021

IJMS

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Dopamine is likely the most studied modulatory neurotransmitter, in great part due to characteristic motor deficits in Parkinson’s disease that arise after the degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNc). The SNc, together with the ventral tegmental area (VTA), play a key role modulating motor responses through the basal ganglia. In contrast to the large amount of existing literature addressing the mammalian dopaminergic system, comparatively little is known in other vertebrate groups. However, in the last several years, numerous studies have been carried out in basal vertebrates, allowing a better understanding of the evolution of the dopaminergic system, especially the SNc/VTA. We provide an overview of existing research in basal vertebrates, mainly focusing on lampreys, belonging to the oldest group of extant vertebrates. The lamprey dopaminergic system and its role in modulating motor responses have been characterized in significant detail, both anatomically and functionally, providing the basis for understanding the evolution of the SNc/VTA in vertebrates. When considered alongside results from other early vertebrates, data in lampreys show that the key role of the SNc/VTA dopaminergic neurons modulating motor responses through the basal ganglia was already well developed early in vertebrate evolution.

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Section: Evolution Of Mesodiencephalic Dopaminergic Neuronssupporting

confidence: 77%

The Dopaminergic Control of Movement-Evolutionary Considerations

Pérez‐Fernández

Barandela

Jiménez-López

2021

IJMS

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“…In zebrafish, the inferior lobe has not developed at the long‐pec stage; it is first identifiable at 5 days postfertilization (Bloch et al., 2019). In teleost fish, the inferior lobe is known as a multisensory integration center that is involved in gustatory (Rink & Wullimann, 1998; Wullimann, 2020), visual (Butler et al., 1991), and octavolateralis systems (Yang et al., 2007). Further studies can use the detailed descriptions of the bitterling brain developmental atlas provided here to uncover the underlying regulatory mechanisms that control such heterochronic development.…”

Section: Discussionmentioning

confidence: 99%

Developmental neuroanatomy of the rosy bitterling Rhodeus ocellatus (Teleostei: Cypriniformes)—A microCT study

Mueller

Rücklin

et al. 2022

J of Comparative Neurology

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Bitterlings are carp‐like teleost fish (Cypriniformes: Acheilanathidae) known for their specialized brood parasitic lifestyle. Bitterling embryos, in fact, develop inside the gill chamber of their freshwater mussel hosts. However, little is known about how their parasitic lifestyle affects brain development in comparison to nonparasitic species. Here, we document the development of the brain of the rosy bitterling, Rhodeus ocellatus, at four embryonic stages of 165, 185, 210, 235 hours postfertilization (hpf) using micro‐computed tomography (microCT). Focusing on developmental regionalization and brain ventricular organization, we relate the development of the brain divisions to those described for zebrafish using the prosomeric model as a reference paradigm. Segmentation and three‐dimensional visualization of the ventricular system allowed us to identify changes in the longitudinal brain axis as a result of cephalic flexure during development. The results show that during early embryonic and larval development, histological differentiation, tissue boundaries, periventricular proliferation zones, and ventricular spaces are all detectable by microCT. The results of this study visualized with differential CT profiles are broadly consistent with comparable histological studies, and with the genoarchitecture of teleosts like the zebrafish. Compared to the zebrafish, our study identifies distinct developmental heterochronies in the rosy bitterling, such as a precocious development of the inferior lobe.

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“…Recently, substantial numbers of midbrain cells (embryonic optic tectum) have been shown to enter the diffuse nucleus of the inferior lobe (Bloch et al., 2019). These cells clearly enter this hypothalamic nucleus via tangential migration, while autochthonic hypothalamic cells contribute to the diffuse nucleus of the inferior lobe via radial migration from the periventricular hypothalamic zone which identifies this nucleus as hypothalamic (Wullimann, 2020).…”

Section: Discussionmentioning

confidence: 99%

A versatile transcription factor: Multiple roles of orthopedia a (otpa) beyond its restricted localization in dopaminergic systems of developing and adult zebrafish (Danio rerio) brains

Bernhardi

Biechl

Miek

et al. 2022

J of Comparative Neurology

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Many transcription factors boost neural development and differentiation in specific directions and serve for identifying similar or homologous structures across species.The expression of Orthopedia (Otp) is critical for the development of certain cell groups along the vertebrate neuraxis, for example, the medial amygdala or hypothalamic neurosecretory neurons. Therefore, the primary focus of the present study is the distribution of Orthopedia a (Otpa) in the larval and adult zebrafish (Danio rerio) brain.Since Otpa is also critical for the development of zebrafish basal diencephalic dopaminergic cells, colocalization of Otpa with the catecholamine synthesizing enzyme tyrosine hydroxylase (TH) is studied. Cellular colocalization of Otpa and dopamine is only seen in magnocellular neurons of the periventricular posterior tubercular nucleus and in the posterior tuberal nucleus. Otpa-positive cells occur in many additional structures along the zebrafish neuraxis, from the secondary prosencephalon down to the hindbrain. Furthermore, Otpa expression is studied in shh-GFP and islet1-GFP transgenic zebrafish.Otpa-positive cells only express shh in dopaminergic magnocellular periventricular posterior tubercular cells, and only colocalize with islet1-GFP in the ventral zone and prerecess caudal periventricular hypothalamic zone and the perilemniscal nucleus.The scarcity of cellular colocalization of Otpa in islet1-GFP cells indicates that the Shh-islet1 neurogenetic pathway is not active in most Otpa-expressing domains. Our analysis reveals detailed correspondences between mouse and zebrafish forebrain territories including the zebrafish intermediate nucleus of the ventral telencephalon and the mouse medial amygdala. The zebrafish preoptic Otpa-positive domain represents the neuropeptidergic supraopto-paraventricular region of all tetrapods. Otpa domains in the zebrafish basal plate hypothalamus suggest that the ventral periventricular hypothalamic zone corresponds to the otp-expressing basal hypothalamic tuberal field in the mouse. Furthermore, the mouse otp domain in the mammillary hypothalamusThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Neural origins of basal diencephalon in teleost fishes: Radial versus tangential migration

Cited by 18 publications

References 54 publications

The Dopaminergic Control of Movement-Evolutionary Considerations

The Dopaminergic Control of Movement-Evolutionary Considerations

Developmental neuroanatomy of the rosy bitterling Rhodeus ocellatus (Teleostei: Cypriniformes)—A microCT study

A versatile transcription factor: Multiple roles of orthopedia a (otpa) beyond its restricted localization in dopaminergic systems of developing and adult zebrafish (Danio rerio) brains

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