Neural Similarity Between Encoding and Retrieval is Related to Memory Via Hippocampal Interactions

Ritchey, Maureen; Wing, Erik A.; LaBar, Kevin S.; Cabeza, Roberto

doi:10.1093/cercor/bhs258

Cited by 278 publications

(318 citation statements)

References 44 publications

Supporting

Mentioning

277

Contrasting

Order By: Relevance

“…Motivated by prior findings, we predicted that priming would be associated with reductions in neural activity across repetitions (repetition suppression; Maccotta and Buckner, 2004;Wig et al, 2005;Zago et al, 2005; Turk-Browne et al, 2006; Epstein et al, 2008), while successful recognition memory would be associated with consistency of representation across repetitions (pattern similarity; Xue et al, 2010;Ritchey et al, 2012). Critically, we sought to determine whether each of these relationships would be present within common, high-level visual cortical areas.…”

Section: Introductionmentioning

confidence: 93%

“…Our finding that similarity across repetitions predicted subsequent recognition replicates the findings of Xue et al (2010), who observed relationships between pattern similarity and subsequent recognition of faces in similar neural regions (e.g., superior LOC). Explicit memory is also positively related to item-level pattern similarity in occipitotemporal regions when comparing encoding and recognition trials (i.e., when an encoded item is "repeated" in a recognition test) (Ritchey et al, 2012). Moreover, within ventral temporal cortex, similarity across different items within a category (e.g., similarity between two different scenes) is positively related to subsequent explicit memory (Kuhl et al, 2012a; LaRocque et al, 2013).…”

Section: Explicit Memorymentioning

confidence: 99%

“…Likewise, fMRI pattern similarity between encoding and recognition of a stimulus relates to the subjective experience of remembering (Ritchey et al, 2012). Thus, consistency in the representation of a stimulus is positively related to explicit memory for that stimulus.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Repetition Suppression and Multi-Voxel Pattern Similarity Differentially Track Implicit and Explicit Visual Memory

2013

View full text Add to dashboard Cite

Repeated exposure to a visual stimulus is associated with corresponding reductions in neural activity, particularly within visual cortical areas. It has been argued that this phenomenon of repetition suppression is related to increases in processing fluency or implicit memory. However, repetition of a visual stimulus can also be considered in terms of the similarity of the pattern of neural activity elicited at each exposure-a measure that has recently been linked to explicit memory. Despite the popularity of each of these measures, direct comparisons between the two have been limited, and the extent to which they differentially (or similarly) relate to behavioral measures of memory has not been clearly established. In the present study, we compared repetition suppression and pattern similarity as predictors of both implicit and explicit memory. Using functional magnetic resonance imaging, we scanned 20 participants while they viewed and categorized repeated presentations of scenes. Repetition priming (facilitated categorization across repetitions) was used as a measure of implicit memory, and subsequent scene recognition was used as a measure of explicit memory. We found that repetition priming was predicted by repetition suppression in prefrontal, parietal, and occipitotemporal regions; however, repetition priming was not predicted by pattern similarity. In contrast, subsequent explicit memory was predicted by pattern similarity (across repetitions) in some of the same occipitotemporal regions that exhibited a relationship between priming and repetition suppression; however, explicit memory was not related to repetition suppression. This striking double dissociation indicates that repetition suppression and pattern similarity differentially track implicit and explicit learning.

show abstract

Section: Introductionmentioning

confidence: 93%

Section: Explicit Memorymentioning

confidence: 99%

See 1 more Smart Citation

Repetition Suppression and Multi-Voxel Pattern Similarity Differentially Track Implicit and Explicit Visual Memory

2013

View full text Add to dashboard Cite

show abstract

“…The increased spatial resolution afforded by such multivariate approaches enables investigation of event-specific cortical reinstatement. Two recent studies (Staresina et al 2012a;Ritchey et al 2013) were able to identify such item-specific reinstatement. Staresina et al (2012a) examined whether item-specific neural representations elicited during episodic encoding are later reinstated during successful recollection.…”

Section: Reinstatement Of Encoding Processes During Retrievalmentioning

confidence: 99%

Memory Retrieval in Mice and Men

Ben-Yakov

Dudai

Mayford

2015

Cold Spring Harb Perspect Biol

View full text Add to dashboard Cite

Retrieval, the use of learned information, was until recently mostly terra incognita in the neurobiology of memory, owing to shortage of research methods with the spatiotemporal resolution required to identify and dissect fast reactivation or reconstruction of complex memories in the mammalian brain. The development of novel paradigms, model systems, and new tools in molecular genetics, electrophysiology, optogenetics, in situ microscopy, and functional imaging, have contributed markedly in recent years to our ability to investigate brain mechanisms of retrieval. We review selected developments in the study of explicit retrieval in the rodent and human brain. The picture that emerges is that retrieval involves coordinated fast interplay of sparse and distributed corticohippocampal and neocortical networks that may permit permutational binding of representational elements to yield specific representations. These representations are driven largely by the activity patterns shaped during encoding, but are malleable, subject to the influence of time and interaction of the existing memory with novel information.

show abstract

“…MVPA, however, is unable to directly examine whether successful retrieval reinstates the neural representations of individual items. Representational similarity analysis supports neural reinstatement of individual stimuli (17)(18)(19), but this alternative fMRI approach does not examine to what extent retrieval reinstates a changing neural representation of context. In addition, the limited temporal resolution of fMRI studies makes them unable to identify the precise spatiotemporal dynamics of neural activity that distinguish successful and unsuccessful retrieval of individual events.…”

mentioning

confidence: 99%

Reinstatement of distributed cortical oscillations occurs with precise spatiotemporal dynamics during successful memory retrieval

Yaffe

Kerr

Damera³

et al. 2014

Proc. Natl. Acad. Sci. U.S.A.

138

134

View full text Add to dashboard Cite

Reinstatement of neural activity is hypothesized to underlie our ability to mentally travel back in time to recover the context of a previous experience. We used intracranial recordings to directly examine the precise spatiotemporal extent of neural reinstatement as 32 participants with electrodes placed for seizure monitoring performed a paired-associates episodic verbal memory task. By cueing recall, we were able to compare reinstatement during correct and incorrect trials, and found that successful retrieval occurs with reinstatement of a gradually changing neural signal present during encoding. We examined reinstatement in individual frequency bands and individual electrodes and found that neural reinstatement was largely mediated by temporal lobe theta and high-gamma frequencies. Leveraging the high temporal precision afforded by intracranial recordings, our data demonstrate that high-gamma activity associated with reinstatement preceded theta activity during encoding, but during retrieval this difference in timing between frequency bands was absent. Our results build upon previous studies to provide direct evidence that successful retrieval involves the reinstatement of a temporal context, and that such reinstatement occurs with precise spatiotemporal dynamics.R einstatement of neural activity is hypothesized to underlie our ability to recover the internal representation of a previous experience, a process described as mental time travel (1-4). These internal representations, which may reflect the external environment or internal mental states, form the context in which an episodic memory is embedded. Central to the hypothesis of mental time travel is that context representations in the brain gradually change over time, and that successful retrieval of an episodic memory involves mentally jumping back in time to reexperience a particular context (5-8). Consistent with this paradigm, when an episode is successfully retrieved from memory, the memory for neighboring episodes that occurred close in time is enhanced, an effect known as contiguity (9). However, despite substantial behavioral data supporting this hypothesis, a number of important yet unanswered questions remain regarding its underlying neural mechanisms.Empiric support for neural reinstatement has largely emerged from functional MRI (fMRI) studies that have used multivoxel pattern analysis (MVPA) (10-12). MVPA relies on classifying neural activity during retrieval to dissociate broad manipulations such as category or task that are present during encoding (13-16). MVPA, however, is unable to directly examine whether successful retrieval reinstates the neural representations of individual items. Representational similarity analysis supports neural reinstatement of individual stimuli (17-19), but this alternative fMRI approach does not examine to what extent retrieval reinstates a changing neural representation of context. In addition, the limited temporal resolution of fMRI studies makes them unable to identify the precise spatiotemporal dynamics o...

show abstract

Neural Similarity Between Encoding and Retrieval is Related to Memory Via Hippocampal Interactions

Cited by 278 publications

References 44 publications

Repetition Suppression and Multi-Voxel Pattern Similarity Differentially Track Implicit and Explicit Visual Memory

Repetition Suppression and Multi-Voxel Pattern Similarity Differentially Track Implicit and Explicit Visual Memory

Memory Retrieval in Mice and Men

Reinstatement of distributed cortical oscillations occurs with precise spatiotemporal dynamics during successful memory retrieval

Contact Info

Product

Resources

About