2005
DOI: 10.1111/j.1365-2303.2005.00246.x
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Neural tumours of the neck presenting as thyroid nodules: a report of three cases

Abstract: Schwannomas of the neck are easily identifiable on cytology compared with MPNST. However, cytology alone is not helpful in identifying the origin of these tumours. As primary neural tumours of the thyroid are rare, the possibility of a soft tissue neural tumour extending into the thyroid should always be ruled out while evaluating these cases.

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Cited by 22 publications
(5 citation statements)
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“…[5]Neck swelling with hoarseness and dysphagiaInconclusiveEnhancing thyroid mass compressing the oesophagusHemi –thyroidectomy (frozen section done: spindle cell tumour)S100 and Vimentin +veSujita et al [6]Asymptomatic neck swellingWell-defined solid thyroid lesionInflammatory cells seen inconclusiveLow-density mass on plain CT and moderately enhancing on contrastHemi-thyroidectomyJayaram [7]Asymptomatic neck swellingHypoechoic nodule USG-guided aspirate; pallisading pattern of spindle cells s/o schwannoma Hemi-thyroidectomyS 100 +ve (done on fine needle aspirate) Both final histology and FNAC slides were indicative of schwannoma Aron et al . (2 cases) [8]Asymptomatic neck swellingHypoechoic nodule with cystic spacesUSG-guided aspirates s/o schwannomaHemi-thyroidectomy Both final histology and FNAC slides were indicative of schwannoma Mikosch et al . [9]Asymptomatic neck swellingHypoechoic thyroid noduleUSG-guided FNAC: suspicious of neural tumourHemothyroidectomy

USG, ultrasonography; FNAC, fine needle aspiration cytology; k/c/o, known case of; s/o, suggestive of; i/v/o, in view of .

…”
Section: Discussionmentioning
confidence: 99%
“…[5]Neck swelling with hoarseness and dysphagiaInconclusiveEnhancing thyroid mass compressing the oesophagusHemi –thyroidectomy (frozen section done: spindle cell tumour)S100 and Vimentin +veSujita et al [6]Asymptomatic neck swellingWell-defined solid thyroid lesionInflammatory cells seen inconclusiveLow-density mass on plain CT and moderately enhancing on contrastHemi-thyroidectomyJayaram [7]Asymptomatic neck swellingHypoechoic nodule USG-guided aspirate; pallisading pattern of spindle cells s/o schwannoma Hemi-thyroidectomyS 100 +ve (done on fine needle aspirate) Both final histology and FNAC slides were indicative of schwannoma Aron et al . (2 cases) [8]Asymptomatic neck swellingHypoechoic nodule with cystic spacesUSG-guided aspirates s/o schwannomaHemi-thyroidectomy Both final histology and FNAC slides were indicative of schwannoma Mikosch et al . [9]Asymptomatic neck swellingHypoechoic thyroid noduleUSG-guided FNAC: suspicious of neural tumourHemothyroidectomy

USG, ultrasonography; FNAC, fine needle aspiration cytology; k/c/o, known case of; s/o, suggestive of; i/v/o, in view of .

…”
Section: Discussionmentioning
confidence: 99%
“…sites of occurrence are at a spinal nerve root, the sciatic nerve, brachial plexus, sacral plexus, as well as peripheral nerves [2,18]. Other uncommonly reported sites of MPNST include: pancreas [19], thyroid [20], tongue [21], bile duct [22], skin [23], prostate [24], breast [25], mediastinum [26], rectum [27], colon [28], cervix [29], mesentery [30], liver [31], abdominal wall [32]. The sites of presentation do not differ significantly in NF1 and non-NF1 patients [2].…”
Section: Demographicsmentioning
confidence: 96%
“…Schwannomas are benign tumors that can develop along the course of any nerve. For unknown reasons, the most frequent schwannomas are located on the acoustic nerve, followed by neurinomas of the facial and the trigeminal nerves [ 13 ]. Therefore, schwannomas of the head and neck region are common, while ones involving the thyroid gland are unusual [ 9 ].…”
Section: Review and Discussionmentioning
confidence: 99%