Neuro/Medical Oncology

Ambady, Prakash; Holdhoff, Matthias; Ferrigno, C; Grossman, Stuart A.; Anderson, Mark D.; Conrad, Charles A.; Penas‐Prado, Marta; Gilbert, Mark R.; Yung, Alfred; Groot, John de; Aoki, Tomokazu; Nishikawa, Ryo; Sakamoto, Kazuhiko; Nonoguchi, Naosuke; Kawabata, Noriyuki; Mishima, Kazuhiko; Adachi, Jun-ichi; Kurisu, Kaoru; Yamasaki, Fumiyuki; Tominaga, Teiji; Kumabe, Toshihiro; Ueki, Keisuke; Higuchi, Fumi; Yamamoto, Tetsuya; Ishikawa, Eiichi; Takeshima, Hideo; Yamashita, Shinji; Arita, Kazunori; Hirano, Hirofumi; Yamada, Shinobu; Matsutani, Masao; Apok, Vino; Mills, Samantha J.; Soh, Calvin; Karabatsou, Konstantina; Arivazhagan, Arimappamagan; Arya, Sneha; Majaid, MA; Somanna, Sampath; Santosh, Vani; Schaff, Lauren; Armentano, Francine; Harrison, C; Lassman, Andrew B.; McKhann, Guy M.; Iwamoto, Fábio M.; Armstrong, Terri S.; Yuan, Ying; Acquaye, Alvina; Vera-Bolaños, Elizabeth; Diefes, Kristin; Heathcock, Lindsey; Cahill, Daniel P.; Aldape, Kenneth; Arrillaga‐Romany, Isabel; Ruddy, Kathryn J.; Greenberg, Steven A.; Nayak, Lakshmi; Avgeropoulos, Nicholas G.; Avgeropoulos, George; Riggs, Garrett; Reilly, Christopher F.; Banerji, Nilanjana; Bruns, Patricia; Hoag, M. S.; Gilliland, Kathryn L.; Trusheim, John; Bekaert, Lien; Borha, Alin; Emery, E. W.; Busson, A; Guillamo, Jean-Sébastien; Bell, M Lediju; Connolly, E. Sander; Khandji, Alexander G.; Blakeley, Jaishri O.; Ye, Xiaobu; Bergner, A. D.; Dombi, Eva; Zalewski, Christopher; Follmer, K.; Halpin, Chris; Fayad, Laura M.; Jacobs, Michael A.; Baldwin, Andrea; Langmead, Shannon; Whitcomb, Trish; Jennings, Dominique; Widemann, Brigitte C.; Plotkin, Scott R.; Brandes, Alba Ariela; Mason, Warren P.; Pichler, Josef; Nowak, Adriana; Gil, Miguel Gil; Saran, Frank; Révil, Cédric; Lutiger, Beatrix; Carpentier, Antoine F.; Milojkovic-Kerklaan, Bojana; Aftimos, P.; Altıntaş, Sevilay; Jager, Agnes; Gladdines, Werner; Lönnqvist, Fredrik; Soetekouw, Patricia M.M.B.; Linde, Myra van; Awada, Ahmad; Schellens, Jan H.M.; Brandsma, Dieta; Brenner, Andrew; Sun, Jessica; Floyd, John R.; Hart, Charles P.; Eng, Clarence; Fichtel, Lisa; Gruslova, Aleksandra; Lodi, Alessia; Tiziani, Stefano; Bridge, Carly; Baldock, Anne; Kumthekar, Priya; Dilfer, Paul; Johnston, Sandra K.; Jacobs, J. R.; Corwin, David; Guyman, Laura; Rockne, Russell; Sonabend, Adam M.; Cloney, Michael; Canoll, Peter; Swanson, Kristin R.; Bromberg, Jacoline E C; Schouten, Harry C.; Schaafsma, Ron; Baars, Joke W.; Lugtenburg, P.J.; Montfort, Cees van; Bent, Martin van den; Doorduijn, Jeanette K.; Spalding, Aaron C.; LaRocca, Renato; Haninger, Diana M.; Saaraswat, Tanuj; Coombs, Lennea; Rai, Shesh; Burton, Eric; Burzynski, Gregory S.; Burzynski, Stanislaw R.; Janicki, Tomek; Marszalek, Ania; Janicki, Tomasz; Cachia, David; Smith, Thomas P.; Cardona, Andrés F.; Mayor, L.; Jiménez, Enrique; Hakim, Fernando; Yepes, Carlos; Bermúdez, Sonia; Useche, Nicolás; Mejía, Juan; Vargas, Carlos; Otero, Jorge; Carranza, Hernán; Ortíz, León Darío; Bartels, Carlos; Quintero, Andrés; Restrepo, Carlos E.; Gómez, Sonia; Bernal-Vaca, Laura; Lema, Mauricio; Carlo, Maria I.; Omuro, Antonio A.; Grommes, Christian; Nolan, Craig; Pentsova, Elena; Pietanza, M. 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Carl; Brat, Daniel J.; Flanders, Adam E.; Jiang, Chuanlu; Wang, Hongjun; Jo, Jasmin; Williams, Brian H.; Smolkin, Mark E.; Wintermark, Max; Shaffrey, Mark E.; Juratli, Tareq A.; Soucek, Silke; Kirsch, M; Schackert, Gabriele; Kakkar, Aanchal; Kumar, Sawan; Bhagat, Utkarsh; Kumar, Anupam; Suri, Ashish; Singh, Manmohan; Sharma, Mehar Chand; Sarkar, Chitra; Suri, Vaishali; Barani, Igor J.; McDermott, Michael W.; Rogers, Leland; Weber, Damien Charles; Kalita, Ondřej; Vaverka, Miroslav; Hrabálek, Lumir; Zlevorová, Miloslava; Trojanec, Radek; Hajdúch, Marián; Kneblova, Magdalena; Ehrmann, Jiří; Kanner, Andrew A.; Wong, Eric T.; Villanó, John L.; Khatua, Soumen; Dasgupta, Soham; Rytting, Michael; Vats, Tribhwan; Zaky, Wafik; Sandberg, David I.; Foresman, Lauren; Kieran, Mark W.; Geoerger, Birgit; Casanova, Michela; Chisholm, Julia; Aerts, Isabelle; Bouffet, Éric; Leary, Sarah E. S.; Sullivan, Michael J.; Bailey, Simon; Cohen, Kenneth J.; Kalambakas, Stacey; Deshpande, Priya; Tian, Feng; Hurh, Eunju; McDonald, Tobey J.; Hargrave, Darren; Goldman, Stewart; Amakye, Dereck D.; Patton, M M; Moreno, Lucas; Kim, Chae-Yong; Kim, Tackeun; Han, Jung Ho; Kim, Yu Jung; Kim, In Ah; Yun, Chang-Ho; Jung, Hee Won; Koekkoek, Johan A F; Reijneveld, Jaap C.; Dirven, Linda; Postma, Tjeerd J.; Vos, Maaike J.; Heimans, Jan J.; Taphoorn, Martin J.B.; Koeppen, S; Hense, Jörg; Kong, Xianguo; Davidson, Tom B.; Lai, Albert; Cloughesy, Timothy F.; Nghiemphu, Phioanh L.; Kong, Doo‐Sik; Choi, Yoon–La; Seol, Ho Jun; Lee, Jung-Il; Nam, Do‐Hyun; Kool, Marcel; Jones, David; Jäger, Natalie; Northcott, Paul A.; Pugh, Trevor J.; Hovestadt, Volker; Markant, Shirley L.; Esparza, Lourdes Adriana; Bourdeaut, Franck; Remke, Marc; Taylor, Michael D.; Cho, Yoon-Jae; Pomeroy, Scott L.; Schüller, Ulrich; Korshunov, Andrey; Eils, Roland; Wechsler‐Reya, Robert J.; Lichter, Peter; Pfister, Stefan M.; Krel, Regina; Krutoshinskaya, Yana; Rosiello, Arthur; Seidman, Roberta; Kowalska, Agnieszka; Kudo, Takumi; Hata, Yutaka; Maehara, Taketoshi; Patel, Vaibhav; Rademaker, Alfred; Helenowski, Irene; Mrugala, Maciej M.; Rockhill, Jason K.; Grimm, Sean; Meletath, Silviya K.; Bennett, Monica; Nestor, Vanessa A.; Fink, Karen; Lee, Eudocia; Reardon, David A.; Drappatz, Jan; Muzikansky, Alona; Hammond, Samantha N.; Norden, Andrew D.; Beroukhim, Rameen; McCluskey, Christine; Chi, Andrew; Batchelor, Tracy T.; Smith, Katrina H.; Gaffey, Sarah; Gerard, Mary; Snodgras, Susan; Leeper, Heather; Johnson, Derek R.; Lima, Judy; Porensky, Emily K.; Cavaliere, Robert; Lin, Andrew; Liu, Jingxia; Evans, John; Leuthardt, Eric C.; Dacey, Ralph G.; Dowling, Joshua L.; Kim, Albert; Zipfel, Gregory J.; Grubb, Robert L.; Huang, Jiayi; Robinson, C.G.; Simpson, Joseph R.; Linette, Gerald P.; Chicoine, Michael R.; Tran, David; Liubinas, Simon V.; D'Abaco, Giovanna M.; Moffat, Bradford A.; Gonzales, Michael; Feleppa, Frank; Nowell, Cameron J.; Gorelick, A.N.; Drummond, Katharine J.; Morokoff, Andrew; O’Brien, Terence J.; Kaye, Andrew H.; Melhem-Bertrandt, Amal; Zaidi, Tanweer M.; Katz, Ruth; Lupica, Kathleen M.; Ly, Ina; Hamilton, Steven; Rostomily, Robert; Yust‐Katz, Shlomit; Pachow, Doreen; Kliese, Nadine; Kirches, Elmar; Mawrin, Christian; McNamara, Mairéad G.; Lwin, Zarnie; Jiang, Haiyan; Chung, Caroline; Millar, Barbara‐Ann; Sahgal, Arjun; Laperrière, Normand; Megyesi, Joseph F.; Salehi, Fateme; Merker, Vanessa; Slusarz, Katie; Francis, Sanjeev; Adachi, Jun-ich; Suzuki, Tomonari; Uchida, Eita; Yanagawa, Taro; Watanabe, Yuko; Fukuoka, Kohei; Yanagisawa, Takaaki; Wakiya, Kenji; Fujimaki, Takamitsu; Moiyadi, Aliasgar; Kannan, Sadhana; Epari, Sridhar; Gupta, Tejpal; Shetty, Prakash; Jalali, Rakesh; Alshami, Jad; Lecavalier-Barsoum, Magali; Guiot, Marie‐Christine; Tampieri, Donatella; Muanza, Thierry; Nagane, Motoo; Kobayashi, Keiichi; Takayama, Nobuki; Shiokawa, Yoshiaki; Nakamura, Hideo; Makino, Keishi; Hideo, Takuichiro; Kuroda, Jun-ichiro; Shinojima, Naoki; Yano, Shigetoshi; Kuratsu, Jun‐ichi; Nambudiri, Navya; Arrilaga, Isabel; Dunn, Ian F.; Folkerth, Rebecca D.; Chi, Susan; Robins, H. Ian; Govindan, Ramaswamy; Gadgeel, Shirish M.; Kelly, Karen; Rigas, James R.; Reimers, Hans-Joachim; Rosenfeld, Steven S.; Garst, Jennifer; Ramnath, Nithya; Wing, P Chan; Zheng, Ming; Urban, Patrick; Abrey, Lauren E.; Soffietti, Riccardo; Lin, Nancy U.; Macdonald, David R.; Galanis, Evanthia; Perry, James; Stupp, Roger; Lesser, Glenn J.; Doherty, Lisa; LaFrankie, Debra C.; Ruland, Sandra; Ligon, Keith L.; Bush, Nancy Ann Oberheim; Kesari, Santosh; Scott, Brian J.; Ohno, Makoto; Narita, Yoshitaka; Miyakita, Yasuji; Arita, Hideyuki; Matsushita, Yuko; Yoshida, Akihiko; Fukushima, Shintaro; Ichimura, Koichi; Shibui, Soichiro; Okamura, Takehiko; Kaneko, Sadao; Taillandier, Luc; Ghesquières, Hervé; Soussain, Carole; Delwail, Vincent; Lamy, Thierry; Gressin, Rémy; Choquet, Sylvain; Soubeyran, Pierre; Maire, Jean Philippe; Benouaich‐Amiel, Alexandra; Lebouvier-Sadot, Sophie; Gyan, Emmanuel; Barrié, Maryline; Rio, Monica Sierra del; González-Aguilar, Alberto; Houllier, Caroline; Tanguy, Marie‐Laure; Paleologos, Nina A.; Forsyth, Peter; Louis, David N.; Cairncross, J. 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J.; Yoon, Wan-Soo; Yang, Seung-Ho; Chung, Dong-Sup; Jeun, Sin‐Soo; Milbourne, Andrea; Liu, Diane; Weinberg, Jeffrey S.; Ketonen, Leena; McAleer, Mary Frances; Ahmed, Nabil; Olar, Adriana; Stewart, John

doi:10.1093/neuonc/not182

Cited by 5 publications

(2 citation statements)

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“…One of these investigations found that LTS reached minimum tumor volume later and had a significantly slower rate of post-radiation tumor growth compared to non-LTS (OS < 3 years) 41 . A second investigation comparing LTS to patients with OS < 500 days, found that LTS were younger, had higher initial KPS, and more commonly had cystic tumors 42 . Another study found that among right temporal GBM patients, LTS had greater contralateral cortical thickness than non-LTS 43 .…”

Section: Preliminary Results From Analysis Of Our Extreme Survivorsmentioning

confidence: 99%

ENvironmental Dynamics Underlying Responsive Extreme Survivors (ENDURES) of Glioblastoma: a Multi-disciplinary Team-based, Multifactorial Analytical Approach

Johnston

Whitmire²,

Massey³

et al. 2018

Preprint

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Although glioblastoma is a fatal primary brain cancer with a short median survival of 15 months, a small number of patients survive more than 5 years after diagnosis; they are known as extreme survivors (ES). Due to their rarity, very little is known about what differentiates these outliers from other glioblastoma patients. For the purpose of identifying unknown drivers of extreme survivorship in glioblastoma, we developed the ENDURES consortium (ENvironmental Dynamics Underlying Responsive Extreme Survivors of glioblastoma). This consortium is a multicenter collaborative network of investigators focused on the integration of multiple types of clinical data and the creation of patient-specific models of tumor growth informed by radiographic and histological parameters. Leveraging our combined resources, the goals of the ENDURES consortium are two-fold: (1) to build a curated, searchable, multilayered repository housing clinical and outcome data on a large cohort of ES patients with glioblastoma and (2) to leverage the ENDURES repository for new insights on tumor behavior and novel targets for prolonging survival for all glioblastoma patients. In this article, we review the available literature and discuss what is already known about ES. We then describe the creation of our consortium and some of our preliminary results.FundingThis review was financially supported by a grant from the James S. McDonnell FoundationConflicts of InterestThe authors have declared that no conflicts of interest exist.AuthorshipConceptualized consortium: LW, RG, KME, PC, and KRS. Built consortium: SKJ, PK, NR, JS, KME, PC, and KRS. Wrote the manuscript: SKJ, PW, SCM, PK, AP, and KME. Reviewed and edited the manuscript: LFGC, MMM, AHD, PRJ, and LSH. Contributed to writing, provided feedback, and approved of final manuscript: All authors.Link to website for ENDUREShttp://mathematicalneurooncology.org/?page_id=2125

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Section: Preliminary Results From Analysis Of Our Extreme Survivorsmentioning

confidence: 99%

ENvironmental Dynamics Underlying Responsive Extreme Survivors (ENDURES) of Glioblastoma: a Multi-disciplinary Team-based, Multifactorial Analytical Approach

Johnston

Whitmire²,

Massey³

et al. 2018

Preprint

View full text Add to dashboard Cite

show abstract

“…Thirty-seven biomarkers related to change in circulating immune cell and other hematopoietic lineage cells were reported in 14 studies (Table A9) (51,55,(66)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76)(77). Six of these studies included treatment with dendritic cell (DC) vaccine immunotherapy with or without additional modalities (51, 71-73, 75, 77).…”

Section: Alterations To Immune Related and Other Circulating Cell Popmentioning

confidence: 99%

Blood Biomarkers of Glioma in Response Assessment Including Pseudoprogression and Other Treatment Effects: A Systematic Review

et al. 2020

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Imaging-based monitoring of disease burden in glioma patients is frequently confounded by treatment effects. Circulating biomarkers could theoretically augment imaging-based response monitoring. This systematic review aimed to present and evaluate evidence for differential expression and diagnostic accuracy of circulating biomarkers with respect to outcomes of tumor response, progression, stable disease, and treatment effects (pseudoprogression, radionecrosis, pseudoresponse, and pseudolesions) in patients undergoing treatment for World Health Organization grades II-IV diffuse astrocytic and oligodendroglial tumors. MEDLINE, EMBASE, Web Of Science, and SCOPUS databases were searched until August 18, 2019, for observational or diagnostic studies on multiple circulating biomarker types: extracellular vesicles, circulating nucleic acids, circulating tumor cells, circulating proteins, and metabolites, angiogenesis related cells, immune cells, and other cell lines. Methodological quality of included studies was assessed using an adapted Quality Assessment of Diagnostic Accuracy Studies-2 tool, and level of evidence (IA-IVD) for individual biomarkers was evaluated using an adapted framework from the National Comprehensive Cancer Network guidelines on evaluating tumor marker utility. Of 13,202 unique records, 58 studies met the inclusion criteria. One hundred thirty-three distinct biomarkers were identified in a total of 1,853 patients across various treatment modalities. Fifteen markers for response, progression, or stable disease and five markers for pseudoprogression or radionecrosis reached level IB. No biomarkers reached level IA. Only five studies contained data for diagnostic accuracy measures. Overall methodological quality of included studies was low. While extensive data on biomarker dysregulation in varying response categories were reported, no biomarkers ready for clinical application were identified. Further assay refinement and evaluation in larger cohorts with diagnostic accuracy study designs are required.

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89Zr as a promising radionuclide and it’s applications for effective cancer imaging

Sarcan

Silindir-Gunay

Özer

et al. 2021

J Radioanal Nucl Chem

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Neuro/Medical Oncology

Cited by 5 publications

References 0 publications

ENvironmental Dynamics Underlying Responsive Extreme Survivors (ENDURES) of Glioblastoma: a Multi-disciplinary Team-based, Multifactorial Analytical Approach

ENvironmental Dynamics Underlying Responsive Extreme Survivors (ENDURES) of Glioblastoma: a Multi-disciplinary Team-based, Multifactorial Analytical Approach

Blood Biomarkers of Glioma in Response Assessment Including Pseudoprogression and Other Treatment Effects: A Systematic Review

89Zr as a promising radionuclide and it’s applications for effective cancer imaging

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