Neuro-ophthalmic and clinical characteristics of brain tumours in a tertiary hospital in Ghana

Tagoe, NN; Essuman, Vera Adobea; Fordjuor, Gladys; Akpalu, Josephine; Bankah, Patrick; Ndanu, Thomas Akuetteh

doi:10.4314/gmj.v49i3.9

Cited by 28 publications

(33 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is very limited data on the patterns of intracranial tumours in Ghana. 12,13 The objective of this study is to determine the pattern of intracranial tumours in neurosurgical patients managed in Korle Bu Teaching Hospital based on the following parameters; demographics, presenting symptoms, spatial distribution and histopathology. This may be extrapolated to the Ghanaian population as Korle Bu Teaching Hospital is the foremost neurosurgical centre in Ghana where majority of the intracranial tumour patients are referred.…”

Section: Introductionmentioning

confidence: 99%

Pattern of intracranial tumours in a tertiary hospital in Ghana

Ekpene¹,

Ametefe²,

Akoto³

et al. 2017

Ghana Medical Journal

View full text Add to dashboard Cite

Objective: This study seeks to describe the pattern of intracranial tumours in Korle Bu Teaching Hospital (KBTH) based on patient demographics, clinical presentation, spatial distribution of tumour and histological findings. Method: The study design is retrospective and descriptive. Data was obtained from the clinical records of patients with intracranial tumours treated in our neurosurgery unit between January 2010 to December 2015, and histology reports obtained from the histopathology unit. Patients with intracranial tumours without definitive histological diagnosis were excluded. Results: Of the 102 histologically diagnosed brain tumours, out of 335 brain tumour cases seen in the period under review, 58 (56.9%) were females and 44 (43.1%) were males (p = 0.031). Gliomas were the commonest intracranial tumours-39(38.2%) followed by Meningiomas 37(36.2%) and Pituitary Adenoma-9(8.8%). Astrocytoma was the commonest type of Glioma comprising 30(77%) of the 39 cases. Meningotheliomatous meningioma was the commonest type of meningioma with 11 (29.7%) of 37 cases. Of the 39 Gliomas 17(43.6%) were males and 22(56.4%) were females, while for the Meningioma 17(46%) were males and 20(54%) were females. The commonest symptom was headache (64%) and the commonest tumour location was supratentorial (77.5%). The crude incidence rate of intracranial tumours in this study was 1.34 per 100,000 populations per year. Conclusion: Gliomas are the commonest intracranial tumours seen in our series. Overall, females were more commonly affected than males in most brain tumours in this series, including both gliomas and meningiomas.

show abstract

Section: Introductionmentioning

confidence: 99%

Pattern of intracranial tumours in a tertiary hospital in Ghana

Ekpene¹,

Ametefe²,

Akoto³

et al. 2017

Ghana Medical Journal

View full text Add to dashboard Cite

show abstract

“…3 With respect to the comment on disparity of tumour frequency between our study 2 and work published from Tema, Ghana 1 , our paper looked at consecutive cases of brain tumours seen at the Eye Unit at Korle Bu Teaching Hospital (KBTH) and found that the commonest brain tumours were pituitary adenoma and meningioma. 2 This is not surprising if one considers the sources of referral of the patients reported in the study.…”

Section: Response To Nb Andrewsmentioning

confidence: 92%

“…The preponderance of evidence from the neurosurgical literature would indicate that this volume is extremely small. 2,3,4 The article advocates, "Education of the public as well as physicians to pick up early signs and symptoms of brain tumours is important to ensure timely diagnosis and management". It may also be worthwhile to urgently institute measures that will provide an adequate caseload for trainee neurosurgeons at the tertiary center in order to ensure that the residents' knowledge of the management of brain tumours is optimised.…”

mentioning

confidence: 99%

Correspondence

Tagoe¹,

Essuman²,

Fordjuor³

et al. 2016

Ghana Medical Journal

View full text Add to dashboard Cite

The above article contains no reference to any peerreviewed paper published on the clinical presentation of brain tumours in Ghana, but at least one such paper is available. 1 The article, however, quotes a reference to research done on Brain Tumours in Ghana from an internet article from a newsite intended for education of the lay public. This newsite is added as part of the formal references for the article. Would it not have been appropriate, therefore, to include relevant peer-reviewed articles from Ghana in the list of references?

show abstract

“…Bitemporal visual field defects were the most prevalent (41%) [8]. Common neuro-ophthalmic manifestations include blurred vision, impairment in colour vision, relative afferent pupillary defect, optic atrophy headache and bitemporal field defect [9]. A study showed that the size of the pituitary adenoma has bearing on its effect as those larger than 2 cm cause defects in vision while those 2 cm or smaller do not cause significant visual impairment [10].…”

Section: Compression Of the Optic Chiasma By Pituitary Tumoursmentioning

confidence: 99%

Clinical Assessment of Lesions Compressing the Visual Pathway

Abdu¹

2019

Optic Nerve

View full text Add to dashboard Cite

There is a close relationship between the visual pathway and other neuro endocrine structures. Tumours and other compressive lesions could often present with visual impairment and/or finite visual field changes. Careful clinical assessment could aid in accurate diagnosis and treatment. Pituitary gland lies in the fossa located in the sphenoid bone. Growth hormone, adreno cortico tropic hormone, and prolactin secreting adenomas could present with respective endocrine features. Optic chiasmal compression by pituitary adenoma is an indicator of suprasellar extension. Meningioma and vestigial remnant craniopharyngioma arise in the parasellar region and can compress on different parts of the optic chiasma often giving rise to classical radiological appearances and visual field changes. This includes atheroma and aneurysm of the internal carotid artery impinging on the temporal chiasma exerting direct pressure and counterpressure on the contralateral side. Others are aneurysms of the precommunicating section of the anterior cerebral artery and those of the posterior communicating artery. Compressive lesions of the visual pathway require a multidisciplinary approach involving neurosurgeon, endocrinologist as well as the ophthalmologist.

show abstract

Neuro-ophthalmic and clinical characteristics of brain tumours in a tertiary hospital in Ghana

Cited by 28 publications

References 17 publications

Pattern of intracranial tumours in a tertiary hospital in Ghana

Pattern of intracranial tumours in a tertiary hospital in Ghana

Correspondence

Clinical Assessment of Lesions Compressing the Visual Pathway

Contact Info

Product

Resources

About