Neuro-Psychological Outcome of ICU-Admitted COVID-19 Patients Presenting With CNS Complications

The authors reply

“…Their study adds new data, as they focused on severe ARDS patients presenting cerebral dysfunction during ICU stay, mostly acute encephalopathy (80%). In comparison with our study published in the journal that reported 4-month follow-up of severe COVID-19–associated ARDS survivors, their findings suggest an improved functional outcome at 1 year (modified Rankin Scale ≤ 2: 28% vs 61% at 4 mo) but a similar rate of persistent cognitive impairment (Montreal Cognitive Assessment < 26, 57% at 1 yr vs 52% at 4 mo) (1, 2).…”

“…We thank Pelle et al (1) for their interest in our study (2). Pelle et al (1) report their multicenter experience on the 1-year follow-up of 64 severe COVID-19 acute respiratory distress syndrome (ARDS) survivors who required invasive mechanical ventilation.…”

“…We thank Pelle et al (1) for their interest in our study (2). Pelle et al (1) report their multicenter experience on the 1-year follow-up of 64 severe COVID-19 acute respiratory distress syndrome (ARDS) survivors who required invasive mechanical ventilation. Their study adds new data, as they focused on severe ARDS patients presenting cerebral dysfunction during ICU stay, mostly acute encephalopathy (80%).…”