Neurobiología de la Patología Dual

Bernal, Luz Angela Rojas; Pérez, Guillermo Alonso Castaño

doi:10.21134/haaj.v17i2.310

Cited by 1 publication

(1 citation statement)

References 99 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, the pre-frontal cortex (PFC) receives dopaminergic projections from the VTA (ventral tegmental area) and noradrenergic projections from the LC (locus coereleus), increasing the release of DA (dopamine) in the PFC. Substances such as amphetamines block NA (noradrenaline) reuptake through the Nat noradrenaline transporter), thus increasing NA levels extracellularly (16,17).…”

Section: ⏐89mentioning

confidence: 99%

The association between the consumption of psychoactive substances and psychiatric disorders in polyconsumers at the Puebla Juvenile Integration Center

Limón Bañuelos,

Vicuña-García,

Limón-Pérez de León

et al. 2024

Rev. Médica Risaralda

View full text Add to dashboard Cite

A retrospective, longitudinal study was conducted on 130 patients aged between 12 and 24 years, in accordance with the corresponding selection criteria and applying the ꭔ2 statistical test and Fisher's exact test, with a confidence interval of 95% and a statistical significance of * p <0.05. The results obtained reveal that 119 (91.5%) patients from the sample group presenteddual pathology, the majority of which were male, among whom marijuana was the most preferred psychoactive substance with 92.4%, followed by alcohol with 60.5%, amphetamines with 52.1%, and cocaine with 40.3%. The average age of the male subjects was 19.32 years ± 3.5. Nine subjects from (6.9%) the female population presented a possible dual pathology, with marijuana identified as the psychoactive substance of choice for 100% of this group, followed by amphetamines with 77.8%, alcohol with 55.6%, and cocaine with 33.3%, while the group’s mean age was 18.44 years ± 4.30. The most statistically significant associations found were marijuana with depression (P *<0.0236), cocaine and amphetamines with anxiety and psychosis (P ***<0.0003 and ***<0.0001, respectively), and amphetamines and post-traumatic stress disorder (PTSD) (P *<0.0132) and the association between alcohol and attention deficit hyperactivity disorder (ADHD) (P **<0.0067)

show abstract

Section: ⏐89mentioning

confidence: 99%