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Introduction. Among patients with mental illness, dual disorders patients are characterized by a heterogeneous and more severe clinical presentation that is difficult to treat. Therefore, knowledge about the distribution of this disorder and the characteristics of these patients can be helpful to optimize and organize health resources. Objective. To explore the prevalence and socio-demographic and clinical factors associated with dual disorders patients who were hospitalized due to mental illness at a psychiatric unit in Colombia between January and June 2013; this data was collected and analyzed on the basis of the medical records of each patient. Method. Observational, quantitative, cross-sectional study of a secondary source. It included the analysis of 201 patients aged 18 to 65. Results. There were 201 patients analyzed; 45.3% had dual disorders, with a ratio of 2.24 men:women; there was a high frequency of single marital status (69.2%) and more than 90% had a low socioeconomic level. The factors significantly associated with dual disorders in order of importance were: age from 18 to 35 years (OR = 11.03; CI 95% [4.43, 27.46]), male (OR = 5.10, CI 95% [2.26, 11.50]), history of aggression (OR = 3.35; CI 95% [1. 63, 6.91]), and readmission in the year after hospital discharge (OR = 2.23; CI 95% [1.08, 4.61]). Discussion and conclusion. Dual disorders prevalence in this study is similar to that found by other authors. The high prevalence of dual disorders requires specialized therapeutic programs for treatment. The more hospitals know about the associated variables in this study, the more they will be able to improve their approach to patients.

ResumenIntroduction. Patients with Dual Pathology are

El mismatch negativity (MMN) es un potencial relacionado con eventos que se ha encontrado alterado en esquizofrenia y consumo de cannabis. Objetivo: evaluar la capacidad predictora y diferencial del MMN en esquizofrenia y consumidores de cannabis. Método: en 23 consumidores de cannabis con esquizofrenia (ESQ+CN), 23 pacientes sin consumo (ESQ) y 21 consumidores de cannabis (CN) se obtuvo el potencial MMN en un EEG de 32 canales. Resultados: para la condición duración, la amplitud del MMNd de ESQ+CN y ESQ fue menor en comparación con CN, mientras que para frecuencia (MMNf) ESQ fue menor que ESQ+CN y CN. No se encontraron diferencias en latencia. En la curva ROC la amplitud del MMNd discriminó el 71.2% de los participantes con esquizofrenia (p =.016) y el MMNf el 82.6% (p = <.001). Conclusiones: el MMNf está asociado con esquizofrenia, mientras el MMNd podría ser útil en el seguimiento de los consumidores de cannabis.