Neurocognitive function profile in HIV-infected school-age children

Koekkoek, Sanneke; Sonneville, Leo de; Wolfs, Tom F. W.; Licht, R.; Geelen, Sibyl P. M.

doi:10.1016/j.ejpn.2007.09.002

Cited by 110 publications

(115 citation statements)

References 40 publications

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“…4 Few studies have demonstrated a neurocognitive deficit in HIV-infected preschool 5,6 and school-aged children. [7][8][9][10][11] Data from HIVinfected children aged from 4 months to 17 years in the United States showed lower cognitive function among the HIVinfected group compared to normal controls. 8 Moreover, cognitive function was not improved after 48 weeks of antiretroviral therapy.…”

mentioning

confidence: 99%

Poor Cognitive Functioning of School-Aged Children in Thailand with Perinatally Acquired HIV Infection Taking Antiretroviral Therapy

Puthanakit

Aurpibul

Louthrenoo

et al. 2010

AIDS Patient Care and STDs

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mentioning

confidence: 99%

Poor Cognitive Functioning of School-Aged Children in Thailand with Perinatally Acquired HIV Infection Taking Antiretroviral Therapy

Puthanakit

Aurpibul

Louthrenoo

et al. 2010

AIDS Patient Care and STDs

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“…Children with AIDS may also have phonological disorders and voice deviances such as hoarseness which was also evidenced in this child along with hypernasality. The children with HIV had deficits in executive functioning and processing speed; however, cognitive delay was not universal [30]. This child reported here did have mild cognitive deficits such as poor judgement skills and altered spatial orientation.…”

Section: Discussionmentioning

confidence: 87%

“…Most commonly, the symptoms manifest as systemic illness once the immune system is majorly affected. Although the primary infection is to the immune system, it may also affect the nervous system causing neurological disorders [6,8,10,14,30]. The child exhibited regression and slurring of speech along with restricted mobility and strength of articulators which support the presence of damage in the brain.…”

Section: Discussionmentioning

confidence: 99%

Speech, language and swallowing difficulties in a child with aids

Narayanan

Kalappa

2017

Acta Oto-Laryngologica Case Reports

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AIDS has a great impact on the modern society as a source of illness and discrimination. It can cause a wide spectrum of disorders which can affect the health and life style of individuals. Globally, the number of individuals with AIDS is increasing and the count of such children is also rising drastically. AIDS caused by HIV is known to invade different systems of the body including the central nervous system thus causing neurological abnormalities/complications in children. Children infected with HIV may present with various types of communication disorders. Speech-language pathologists have investigated and reported the assessment and treatment of HIV-infected individuals in the past. However, studies are limited in the line of profiling the nature of communication and swallowing deficits seen in them. The present case study reports a detailed speech, language and swallowing profile of a child infected with HIV. Effective combination of medical and non-medical treatment for the HIV infection witnessed a great deal of improvement in this child. The importance of care and precautions to be considered while treating such children is highlighted. ARTICLE HISTORY

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“…8,10 The task was adapted and extended from so-called tracking and pursuit tasks that are widely used and validated for studying visuomotor performance in a variety of clinical populations. [17][18][19] During the task, children followed the trail of a moving caterpillar with the index finger of their preferred hand. There were two conditions.…”

Section: Methodsmentioning

confidence: 99%

The crucial role of the predictability of motor response in visuomotor deficits in very preterm children at school age

Kieviet

Stoof

Geldof

et al. 2013

Develop Med Child Neuro

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DCDDevelopmental No group difference in visuomotor performance was present for the structured condition. In the non-structured condition, children born very preterm with and without a research diagnosis of DCD had poorer visuomotor performance than those born at term. INTERPRETATIONThe predictability of the required motor response plays a crucial role in visuomotor deficits in very preterm children, regardless of DCD status.Children born very preterm (<32wks' gestation) are vulnerable to poor visuomotor development throughout childhood and adolescence. 1 This plays a key role in their exploration of the world, academic performance, sporting abilities, involvement in social activities, and self-efficacy. 2,3 In recent literature, visuomotor performance of very preterm children has been commonly described with the widely used Beery-Buktenica Developmental Test of Visual-Motor Integration, 4 indicating widespread visuomotor integration deficits closely interrelated with poor motor performance.5 Although these outcomes clearly illustrate the negative impact of very preterm birth on visuomotor skills and related motor performance, there is a lack of understanding of the underlying mechanisms of visuomotor problems in very preterm children, which hampers opportunities for efficient treatment.Several studies have described the crucial role of internal models of motor planning and continuous motor control in visuomotor performance of typically developing children.6,7 During a visuomotor task, the nervous system has to predict the future location of a moving limb, thereby integrating efferent and afferent signals, eventually altering responses to any changes in the environment during the course of movement. By having internal models or representations of intended actions, predicting the outcome of movements can be processed much quicker in the brain than when a person has to rely on relatively slow sensory-feedback information, thereby providing efficiency to the brain's motor system. 8 Recent studies suggest that visuomotor problems in children with developmental coordination disorder (DCD) are related to specific 'internal modelling deficits', 9,10 which limit their ability to generate accurately and use internal models of motor planning and continuous motor control. Interestingly, the incidence of DCD in very preterm children is on average more than six times higher than in term peers.11 However, it is unclear whether deficits in internal models of motor planning and continuous motor control also underpin the widespread visuomotor problems of very preterm children.In this study, we first assessed the severity of motor deficits in a cohort of 58 very preterm children and 64 age-matched comparison children born at term using the Movement Assessment Battery for Children (M-ABC) as a comprehensive measure of motor functioning. 12 Secondly, the underpinnings of visuomotor problems in very preterm children were investigated using a novel visuomotor task, which tested visuomotor performance under a systematic increase in wor...

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Neurocognitive function profile in HIV-infected school-age children

Cited by 110 publications

References 40 publications

Poor Cognitive Functioning of School-Aged Children in Thailand with Perinatally Acquired HIV Infection Taking Antiretroviral Therapy

Poor Cognitive Functioning of School-Aged Children in Thailand with Perinatally Acquired HIV Infection Taking Antiretroviral Therapy

Speech, language and swallowing difficulties in a child with aids

The crucial role of the predictability of motor response in visuomotor deficits in very preterm children at school age

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