Neurocysticercosis: updated concepts about an old disease

Garcı́a, Héctor H.; Brutto, Oscar H. Del

doi:10.1016/s1474-4422(05)70194-0

Cited by 475 publications

(428 citation statements)

References 80 publications

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“…After ingestion, dissemination via the bloodstream occurs and may remain localized in its cystic form in skeletal muscle, subcutaneous or ocular tissue, brain, or bone marrow. If the larval form is ingested after eating poorly cooked pork that is infected with the cyst, evagination of the cyst will give rise to adult T. solium, which remains in the small intestine (129).…”

Section: Other Parasitic Infectionsmentioning

confidence: 99%

Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation

et al. 2008

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SUMMARY In recent years, the increasing number of donors from different regions of the world is providing a new challenge for the management and selection of suitable donors. This is a worldwide problem in most countries with transplantation programs, especially due to the increase in immigration and international travel. This paper elaborates recommendations regarding the selection criteria for donors from foreign countries who could potentially transmit tropical or geographically restricted infections to solid-organ transplant recipients. For this purpose, an extensive review of the medical literature focusing on viral, fungal, and parasitic infections that could be transmitted during transplantation from donors who have lived or traveled in countries where these infections are endemic has been performed, with special emphasis on tropical and imported infections. The review also includes cases described in the literature as well as risks of transmission during transplantation, microbiological tests available, and recommendations for each infection. A table listing different infectious agents with their geographic distributions and specific recommendations is included.

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Section: Other Parasitic Infectionsmentioning

confidence: 99%

Transmission of Tropical and Geographically Restricted Infections during Solid-Organ Transplantation

et al. 2008

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“…A neurocisticercose (NCC) humana é patologia diretamente relacionada à presença de fases larvais de Taenia solium no sistema nervoso central 1 . Os sinais e sintomas desta infecção independem da viabilidade do parasito, ocorrendo durante ou depois do processo inflamatório causado pela presença de formas intracerebrais vivas ou mortas, degeneradas ou calcificadas 2 .…”

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Perfil clínico-epidemiológico de pacientes com neurocisticercose atendidos no Hospital Universitário Regional de Maringá, Paraná, Brasil

Benedeti

Falavigna

Falavigna-Guilherme

et al. 2007

Arq. Neuro-Psiquiatr.

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Este estudo propõe-se verificar o perfil clínico-epidemiológico da neurocisticercose (NCC) em pacientes atendidos no Hospital Universitário Regional de Maringá. Foram analisados 6100 prontuários dos setores de Neurologia, Neuropediatria, Neurocirurgia e Psiquiatria, de janeiro/1998 a dezembro/2004. Destes, foram selecionados 48 com diagnóstico de NCC. O número de casos de NCC observados superou aqueles notificados à Vigilância Epidemiológica nos anos de 1998, 1999, 2001, 2002 e 2004. Houve predomínio do gênero feminino (p<0,001), com idade entre 31-60 anos (43,7%) e residentes na zona urbana (93,8%). A epilepsia por NCC (IC=1,77;16,07; p=0,0024) foi de início tardio e generalizada em 91,7% dos pacientes, estando associada a cefaléia em 37,5% dos pacientes. Houve necessidade de internação em 22,9% dos pacientes, com tempo médio de internação de 3,91±3,35dias. Concluiu-se que o perfil clínico-epidemiológico observado é peculiar, apresentando alguns pontos em comum com estudos conduzidos em outras regiões endêmicas brasileiras.

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“…Because of its rarity, the management of spinal NCC is poorly defined, but surgical intervention is commonly recommended 2,3 . In non-acute intradural intramedullary spinal cysticercosis, however, several case reports describe successful outcomes with the use of anthelmintic agents alone, and emphasize the need for accurate pre-operative imaging to avoid surgery in selected cases 15 .…”

Section: Discussionmentioning

confidence: 99%

“…While the natural history of human NCC is poorly understood, natural epidemiological observations have shown that most patients develop symptoms within two to five years after exposure 3 . The patient was only two-years-old when she left her home country of El Salvador in 1973; her initial symptoms and the concomitant diagnosis of aseptic meningitis manifested in 1999, about 26 years later.…”

Section: Discussionmentioning

confidence: 99%