Neuroendoscopic biopsy: analysis of a series of 80 patients

Ros-Sanjuán, Ángela; López, Bienvenido Ros; Ibáñez-Botella, Guillermo; Domínguez-Páez, Miguel; Carrasco-Brenes, Antonio; Arráez-Sánchez, Miguel Ángel

doi:10.1007/s10143-018-1046-x

Cited by 6 publications

(3 citation statements)

References 35 publications

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“…There is no doubt that a lack of biopsies preoperatively will be controversial for this surgical algorithm because biopsies can provide a histologic diagnosis preoperatively and one-third of such patients will not require an operative resection (36). However, the risks of biopsy, extensive tissue heterogeneity, and mixed cell populations of pineal region lesions make the use of biopsies limited (37). Additionally, the lack of suitable equipment and technology in developing countries further limits the use of biopsies.…”

Section: Surgical Algorithm For Pineal Region Lesionsmentioning

confidence: 99%

Optimal therapeutic strategies for pineal region lesions

Huang,

Wang,

et al. 2023

Front. Neurol.

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BackgroundThe removal of pineal region lesions are challenging, and therapeutic strategies for their removal remain controversial. The current study was conducted to identify the characteristics and the optimal therapeutic strategies for pineal region lesions.MethodsThis retrospective study reviewed the treatments of 101 patients with pineal region lesions, and different characteristics and therapeutic strategies were observed.ResultsThere were no statistical differences in the total resection ratio, complications, and prognosis outcomes between the hydrocephalus group and non-hydrocephalus group, except patients in the hydrocephalus group were younger and pediatric patients had an increased level of intracranial infections. Treatments of lesions and hydrocephalus secondary to pineal region lesions were two integral parts to therapeutic strategies. For the management of lesions, germinoma or non-germinoma were diagnosed preoperatively, and resection or diagnostic radiation were chosen to deal with pineal region lesions. Endoscopic-assisted surgery provided a higher total resection rate. For the management of hydrocephalus, endoscopic third ventriculostomy (ETV) had the better therapeutic effect. Additionally, cerebrospinal fluid (CSF) diversion before radiotherapy or resection did not improve prognosis outcome, but it was necessary for patients with severe hydrocephalus. Logistical regression analysis indicated that age, lesion size, reoperation ratio, and intracranial complications were predictors of prognosis outcome.ConclusionMore attention should be paid to intracranial infections in pediatric patients with hydrocephalus secondary to pineal region lesions, and CSF diversion before radiotherapy or resection did not promote prognosis outcome, but it was necessary for patients with severe hydrocephalus. Age, lesion size, reoperation ratio, and intracranial complications may be the predictors of prognosis outcome. Most importantly, the surgical algorithm for pineal region lesions which was based on preoperatively diagnosis (non-germinoma and germinoma) is useful, especially for developing countries.

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Section: Surgical Algorithm For Pineal Region Lesionsmentioning

confidence: 99%

Optimal therapeutic strategies for pineal region lesions

Huang,

Wang,

et al. 2023

Front. Neurol.

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“…Moreover, when biopsy the tumor in a deeper location such as the stellar or pineal region, there is high risk for bleeding. 12,13 Therefore, an alternative method that can clearly distinguish the different pathological types of germ cell tumors is necessary.…”

Section: Data Conclusionmentioning

confidence: 99%

“…However, iGCTs are a class of heterogeneous tumors that exhibit histological and biological specificity; the sample obtained during biopsy can only reflect local features and provide limited value in making diagnosis. Moreover, when biopsy the tumor in a deeper location such as the stellar or pineal region, there is high risk for bleeding 12,13 . Therefore, an alternative method that can clearly distinguish the different pathological types of germ cell tumors is necessary.…”

mentioning

confidence: 99%

Multiparametric Framework Magnetic Resonance Imaging Assessment of Subtypes of Intracranial Germ Cell Tumors Using Susceptibility Weighted Imaging, Diffusion‐Weighted Imaging, and Dynamic Susceptibility‐Contrast Perfusion‐Weighted Imaging Combined With Conventional Magnetic Resonance Imaging

Wang

Zhang

et al. 2022

Magnetic Resonance Imaging

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Background: Intracranial germ cell tumors (iGCTs) are classified into two pathological subtypes (germinomas [GEs] and nongerminomatous germ cell tumors [NGGCTs]), with distinct treatment strategy and prognosis. Accurate preoperative determination of iGCT subtypes is essential to guide clinical decision-making and prognosis assessment. Purpose: To investigate the diagnostic value of diffusion-weighted imaging (DWI), susceptibility weighted imaging (SWI), and dynamic susceptibility-contrast perfusion-weighted imaging (DSC-PWI) combined with conventional magnetic resonance imaging (cMRI) in finding subtypes of iGCTs. Study Type: Retrospective. Population: A total of 40 patients (45% male and 55% female) with iGCTs.

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