Role of endoscopic surgical biopsy in diagnoses of intraventricular/periventricular tumors: review of literature including a monocentric case series

D’Angelo, Luca; Armocida, Daniele; Sampirisi, Luigi; Paglia, Francesco; Berra, Luigi Valentino; Santoro, Antonio

doi:10.1007/s13760-020-01299-1

Cited by 7 publications

(8 citation statements)

References 85 publications

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“…MRI-based radiomics is a non-invasive modality that has become a special area of interest in the grading of tumors. Traditionally, a stereotactic-guided needle biopsy (SNB) along with a standard surgical resection are the gold standard methods of tumor diagnosis and grading followed by a subsequent histopathological and genomic diagnosis [25][26][27]. However, an SNB is an invasive clinical procedure and thus runs the risk of surgical complications (e.g., infection, intracerebral hemorrhage) [25,26,28].…”

Section: Implications Of Radiomics In An Lgg Diagnosismentioning

confidence: 99%

“…Traditionally, a stereotactic-guided needle biopsy (SNB) along with a standard surgical resection are the gold standard methods of tumor diagnosis and grading followed by a subsequent histopathological and genomic diagnosis [25][26][27]. However, an SNB is an invasive clinical procedure and thus runs the risk of surgical complications (e.g., infection, intracerebral hemorrhage) [25,26,28]. Additionally, samples collected through an SNB are not necessarily an accurate representation of the whole tumor landscape as gliomas are known to be heterogeneous and the classical SNB may not always reflect the phenotype of the entire tumor or perhaps miss important genomic aberrations in the lesion [29,30].…”

Section: Implications Of Radiomics In An Lgg Diagnosismentioning

confidence: 99%

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MRI-Based Radiomics and Radiogenomics in the Management of Low-Grade Gliomas: Evaluating the Evidence for a Paradigm Shift

Habib

Jovanovich

Hoppe

et al. 2021

JCM

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Low-grade gliomas (LGGs) are tumors that affect mostly adults. These neoplasms are comprised mainly of oligodendrogliomas and diffuse astrocytomas. LGGs remain vexing to current management and therapeutic modalities although they exhibit more favorable survival rates compared with high-grade gliomas (HGGs). The specific genetic subtypes that these tumors exhibit result in variable clinical courses and the need to involve multidisciplinary teams of neurologists, epileptologists, neurooncologists and neurosurgeons. Currently, the diagnosis of an LGG pivots mainly around the preliminary radiological findings and the subsequent definitive surgical diagnosis (via surgical sampling). The introduction of radiomics as a high throughput quantitative imaging technique that allows for improved diagnostic, prognostic and predictive indices has created more interest for such techniques in cancer research and especially in neurooncology (MRI-based classification of LGGs, predicting Isocitrate dehydrogenase (IDH) and Telomerase reverse transcriptase (TERT) promoter mutations and predicting LGG associated seizures). Radiogenomics refers to the linkage of imaging findings with the tumor/tissue genomics. Numerous applications of radiomics and radiogenomics have been described in the clinical context and management of LGGs. In this review, we describe the recently published studies discussing the potential application of radiomics and radiogenomics in LGGs. We also highlight the potential pitfalls of the above-mentioned high throughput computerized techniques and, most excitingly, explore the use of machine learning artificial intelligence technologies as standalone and adjunct imaging tools en route to enhance a personalized MRI-based tumor diagnosis and management plan design.

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Section: Implications Of Radiomics In An Lgg Diagnosismentioning

confidence: 99%

Section: Implications Of Radiomics In An Lgg Diagnosismentioning

confidence: 99%

MRI-Based Radiomics and Radiogenomics in the Management of Low-Grade Gliomas: Evaluating the Evidence for a Paradigm Shift

Habib

Jovanovich

Hoppe

et al. 2021

JCM

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“…In the beginning, neuroendoscopic procedures were limited to the ventricles (ventriculostomy). Today, however, navigated neuroendoscopy is used to treat a wide range of intracranial pathologies in and outside the ventricles, including biopsy, resection of intraventricular lesions such as colloid cysts and small avascular tumours, intraparenchymal tumour biopsy or resection, resection of the sellar, midline, anterior skull base, and pineal region tumours, cyst or abscess evacuation, cyst fenestration, implantation of radioactive seeds, marsupialisation, endoscopic suturectomy in scaphocephaly, and as an adjunct to microscope-used procedures [142,[147][148][149][150][151][152].…”

Section: Neuroendoscopic Surgerymentioning

confidence: 99%

“…Neuronavigation can be used in conjunction with neuroendoscopy to select the optimal burr hole or neuroendoport position and to choose the safest trajectory to the lesion, reducing the risk of damage to vital structures [140,142,147]. Furthermore, in endoscope-assisted surgery, the endoscope can be used as an adjunct to traditional microscopic surgery for final inspection of the resection cavity, as it provides an oblique view [148,155].…”

Section: Neuroendoscopic Surgerymentioning

confidence: 99%

Neurosurgical Approaches to Brain Tissue Harvesting for the Establishment of Cell Cultures in Neural Experimental Cell Models

et al. 2021

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In recent decades, cell biology has made rapid progress. Cell isolation and cultivation techniques, supported by modern laboratory procedures and experimental capabilities, provide a wide range of opportunities for in vitro research to study physiological and pathophysiological processes in health and disease. They can also be used very efficiently for the analysis of biomaterials. Before a new biomaterial is ready for implantation into tissues and widespread use in clinical practice, it must be extensively tested. Experimental cell models, which are a suitable testing ground and the first line of empirical exploration of new biomaterials, must contain suitable cells that form the basis of biomaterial testing. To isolate a stable and suitable cell culture, many steps are required. The first and one of the most important steps is the collection of donor tissue, usually during a surgical procedure. Thus, the collection is the foundation for the success of cell isolation. This article explains the sources and neurosurgical procedures for obtaining brain tissue samples for cell isolation techniques, which are essential for biomaterial testing procedures.

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“…However, the correct prediction of tumor molecular typing is still the bottleneck of traditional radiology. Gliomas of the same histological grade may have radically different prognoses due to different molecular phenotypes, which are difficult to identify from preoperative conventional radiology and can only rely on histopathology and molecular detection after surgical resection [4]. Nevertheless, surgery is an invasive clinical method, and the prognosis of glioma is closely related to the extent of surgical resection.…”

Section: Introductionmentioning

confidence: 99%

A Survey of Radiomics in Precision Diagnosis and Treatment of Adult Gliomas

Chen

et al. 2022

JCM

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Glioma is the most common primary malignant tumor of the adult central nervous system (CNS), which mostly shows invasive growth. In most cases, surgery is often difficult to completely remove, and the recurrence rate and mortality of patients are high. With the continuous development of molecular genetics and the great progress of molecular biology technology, more and more molecular biomarkers have been proved to have important guiding significance in the individualized diagnosis, treatment, and prognosis evaluation of glioma. With the updates of the World Health Organization (WHO) classification of tumors of the CNS in 2021, the diagnosis and treatment of glioma has entered the era of precision medicine in the true sense. Due to its ability to non-invasively achieve accurate identification of glioma from other intracranial tumors, and to predict the grade, genotyping, treatment response, and prognosis of glioma, which provides a scientific basis for the clinical application of individualized diagnosis and treatment model of glioma, radiomics has become a research hotspot in the field of precision medicine. This paper reviewed the research related to radiomics of adult gliomas published in recent years and summarized the research proceedings of radiomics in differential diagnosis, preoperative grading and genotyping, treatment and efficacy evaluation, and survival prediction of adult gliomas.

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Role of endoscopic surgical biopsy in diagnoses of intraventricular/periventricular tumors: review of literature including a monocentric case series

Cited by 7 publications

References 85 publications

MRI-Based Radiomics and Radiogenomics in the Management of Low-Grade Gliomas: Evaluating the Evidence for a Paradigm Shift

MRI-Based Radiomics and Radiogenomics in the Management of Low-Grade Gliomas: Evaluating the Evidence for a Paradigm Shift

Neurosurgical Approaches to Brain Tissue Harvesting for the Establishment of Cell Cultures in Neural Experimental Cell Models

A Survey of Radiomics in Precision Diagnosis and Treatment of Adult Gliomas

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