Neurogene oder idiopathische Detrusorüberaktivität nach erfolgloser antimuskarinerger Therapie

Abstract

Antimuscarinic drugs are regarded as the standard treatment of detrusor overactivity (DO). However, side effects and lack of efficacy cause patients to discontinue long-term therapy. We evaluated the clinical efficacy of functional external electrostimulation (FES) as "second-line" therapy in patients with symptomatic idiopathic or neurogenic DO.In a retrospective study, 52 patients (38 women and 14 men) were evaluated at least 1 year after FES. Eighteen patients (32.7%) regarded FES as successful. No change occurred in 34 patients (65.4%) and 1 patient reported worsening of symptoms. Treatment success lasted for 13.2 months. In successfully treated patients, voiding frequency was significantly reduced from 13.3/24 h to 6.1/24 h under FES and to 6.75/24 h at follow-up. FES is a clinically useful, well-tolerated, conservative second-line treatment option after failed antimuscarinic treatment in patients with idiopathic or neurogenic DO.

Effects of Physiotherapy in the Treatment of Neurogenic Bladder in Patients Infected With Human T-Lymphotropic Virus 1

“…In the present study we used electrical stimulation with a low-frequency current and high pulse width, with a greater time of stimulation for patients with DO. Pannek et al 26 used lower parameters and obtained a decrease in urinary symptoms in 18 (32.7%) of 52 patients with neurogenic DO. The medium-frequency currents were used for patients with acontractile bladder, hypocontractile bladder and DSD.…”