Neurologic Disorders Associated with Gastrointestinal Diseases and Nutritional Deficiencies

Peripheral neuropathy in cystic fibrosis: A prevalence study

“…Whether subnormal values of vitamin E prior to diagnosis can give rise to subclinical electrophysiological abnormalities is a matter worth investigating. Treatment with adequate dosage of vitamin E improves the neurological manifestations by as early as 6 months, but it can take even more than a year [7]. Moreover, in patients who are diagnosed at a later age, therapy mostly halts the disease progression without significantly altering the changes that have already taken place [26].…”

“…Studies in children with cystic fibrosis have shown biochemical vitamin E deficiencies in 90-95% of cases [4][5][6]. Vitamin E deficiency causes various neurological complications including peripheral neuropathy [7].…”