Neuronavigation for Intracranial Meningiomas

Silva, Erasmo Barros da; Milano, Jerônimo Buzetti; Silva, Luis Fernando Moura da; Aurich, Lucas Alves; Ramina, Ricardo

doi:10.5772/29456

Cited by 4 publications

(4 citation statements)

References 30 publications

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“…Studies have correlated the antioxidant potential of L. ferrea extracts with the presence of phenols [11,12], which exert antioxidant activities by preventing or retarding oxidation via the blockade/capture of free radicals [13]. It has been proposed that juca can act as an exogenous antioxidant by preventing free radicals from interacting with fundamental molecules of the organism to cause cellular instability and trigger pathologies such as cancer [14].…”

Section: Introductionmentioning

confidence: 99%

Aqueous ethanol extract of Libidibia ferrea (Mart. Ex Tul) L.P. Queiroz (juca) exhibits antioxidant and migration-inhibiting activity in human gastric adenocarcinoma (ACP02) cells

et al. 2020

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Libidibia ferrea (juca) is a plant belonging to the Fabaceae (Leguminosae) family, whose antioxidant activity has been widely described in the literature. We evaluated this parameter of Aqueous ethanol extract (AE), ethyl acetate (ACO), chloroform (CLO) and hexane (HEX) extracts of L. ferrea. We then tested the most active extract for its toxicity and ability to inhibit migratory activity in the ACP02 gastric adenocarcinoma cell line in vitro. The AE and ACO extracts both had antioxidant activity, the AE extract showing greater potential. This may reflect that both extracts contained phenolic compounds. Although AE extract showed no cytotoxic, mutagenic or genotoxic effect, it altered cell morphology and migration activity. Analysis of apoptosis/necrosis indicated that this parameter does not appear to account for the apparent ability of AE to inhibit cancer cell migration. We speculate that the morphological changes in AE-treated cells could be due to cytoskeleton alterations related to the presence of myo-inositol in AE extract. Together, our results demonstrate this extract of L. ferrea can act as an exogenous antioxidant and might prove useful in efforts to fight secondary tumors.

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Section: Introductionmentioning

confidence: 99%

Aqueous ethanol extract of Libidibia ferrea (Mart. Ex Tul) L.P. Queiroz (juca) exhibits antioxidant and migration-inhibiting activity in human gastric adenocarcinoma (ACP02) cells

et al. 2020

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“…In the same way, stereotaxis and neuronavigation came to facilitate pre-and intraoperative planning, since they provide the location of intracranial structures, in real time, on the previously acquired imaging exams. 51 However, even if these images supply important details for the preoperative planning, some difficulties still persist in the differentiation between tumor lesions and the underlying cerebral structures. Additive manufacturing technology allowed the MRI data to be transduced into tailor-made biomodels describing the relationship between tumor, vasculature, and cerebral tissue, facilitating the understanding and, consequently, resulting in the planning of the most effective treatment.…”

Section: Additive Manufacturing In Neurosurgerymentioning

confidence: 99%

Clinical Applications of Additive Manufacturing Models in Neurosurgery: a Systematic Review

Leal

Ramina

Aguiar

et al. 2021

Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

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Introduction Three-dimensional (3D) printing technologies provide a practical and anatomical way to reproduce precise tailored-made models of the patients and of the diseases. Those models can allow surgical planning, besides training and surgical simulation in the treatment of neurosurgical diseases. Objective The aim of the present article is to review the scenario of the development of different types of available 3D printing technologies, the processes involved in the creation of biomodels, and the application of those advances in the neurosurgical field. Methods We searched for papers that addressed the clinical application of 3D printing in neurosurgery on the PubMed, Ebsco, Web of Science, Scopus, and Science Direct databases. All papers related to the use of any additive manufacturing technique were included in the present study. Results Studies involving 3D printing in neurosurgery are concentrated on three main areas: (1) creation of anatomical tailored-made models for planning and training; (2) development of devices and materials for the treatment of neurosurgical diseases, and (3) biological implants for tissues engineering. Biomodels are extremely useful in several branches of neurosurgery, and their use in spinal, cerebrovascular, endovascular, neuro-oncological, neuropediatric, and functional surgeries can be highlighted. Conclusions Three-dimensional printing technologies are an exclusive way for direct replication of specific pathologies of the patient. It can identify the anatomical variation and provide a way for rapid construction of training models, allowing the medical resident and the experienced neurosurgeon to practice the surgical steps before the operation.

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“…Using Monte Carlo simulations, many authors have obtained the dynamic exponents θ and z as well as the static ones β and ν, and other specific exponents for many different models and situations: Baxter-Wu [17], 2, 3 and 4-state Potts [18,19], Ising with multispin interactions [20], models with no defined Hamiltonian (celular automata and contact process) [21][22][23], models with tricritical point [24], Heisenberg [25], protein folding [26,27], propagation of damages in Ising models [28].…”

Section: Critical Dynamics Of Spin Systems and Time Dependent Simulat...mentioning

confidence: 99%

Generalized Metropolis dynamics with a generalized master equation: An approach for time-independent and time-dependent Monte Carlo simulations of generalized spin systems

2012

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The extension of Boltzmann-Gibbs thermostatistics, proposed by Tsallis, introduces an additional parameter q to the inverse temperature β. Here, we show that a previously introduced generalized Metropolis dynamics to evolve spin models is not local and does not obey the detailed energy balance. In this dynamics, locality is only retrieved for q = 1, which corresponds to the standard Metropolis algorithm. Nonlocality implies very time-consuming computer calculations, since the energy of the whole system must be reevaluated when a single spin is flipped. To circumvent this costly calculation, we propose a generalized master equation, which gives rise to a local generalized Metropolis dynamics that obeys the detailed energy balance. To compare the different critical values obtained with other generalized dynamics, we perform Monte Carlo simulations in equilibrium for the Ising model. By using short-time nonequilibrium numerical simulations, we also calculate for this model the critical temperature and the static and dynamical critical exponents as functions of q. Even for q = 1, we show that suitable time-evolving power laws can be found for each initial condition. Our numerical experiments corroborate the literature results when we use nonlocal dynamics, showing that short-time parameter determination works also in this case. However, the dynamics governed by the new master equation leads to different results for critical temperatures and also the critical exponents affecting universality classes. We further propose a simple algorithm to optimize modeling the time evolution with a power law, considering in a log-log plot two successive refinements.

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Neuronavigation for Intracranial Meningiomas

Abstract: Brazil 2. Frame-based versus frameless image-guided surgery Frame-based stereotactic resection was the first navigation method, rooted in cartesian coordinate system developed by Clarke and Horsley in the 1900s, and is still traditionally www.intechopen.com

Cited by 4 publications

References 30 publications

Aqueous ethanol extract of Libidibia ferrea (Mart. Ex Tul) L.P. Queiroz (juca) exhibits antioxidant and migration-inhibiting activity in human gastric adenocarcinoma (ACP02) cells

Aqueous ethanol extract of Libidibia ferrea (Mart. Ex Tul) L.P. Queiroz (juca) exhibits antioxidant and migration-inhibiting activity in human gastric adenocarcinoma (ACP02) cells

Clinical Applications of Additive Manufacturing Models in Neurosurgery: a Systematic Review

Generalized Metropolis dynamics with a generalized master equation: An approach for time-independent and time-dependent Monte Carlo simulations of generalized spin systems

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