Neuropharmacological actions of <i>Portulaca oleracea</i> V. <i>sativa</i>

Radhakrishnan, R.; Zakaria, Mohamed; Islam, M. W.; Ismail, Amel F.M.; Habibullah, Muzafar Shah; Chan, Kitman

doi:10.1111/j.2042-7158.1998.tb02425.x

Cited by 71 publications

(78 citation statements)

References 3 publications

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“…18,19 Much work has been carried out on different chicory varieties in various regions of Italy to assess their content of phenolic compounds 20 and their antioxidant activities, 21,22 though only a few papers deal with U. dioica. 23 No research at all has been performed on the phenolic profiles of T. porrifolius and V. eriocarpa.…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of flavonoid content in assessing quality of wild and cultivated vegetables for human consumption

et al. 2007

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BACKGROUND: Owing to the demand for 'health foods', commercial development of wild vegetables may find a sizable market niche if adequate agricultural methods are used to domesticate such species. Available techniques of cultivation (even in traditional farming) may provide many advantages, such as enhancement of the content of active principles in plants and improvement in the quality of the raw material to be processed on an industrial scale. In this context, the flavonoid composition and content of roots and leaves from five varieties of wild herbs (Cichorium intybus, Portulaca oleracea, Tragopogon porrifolius, Urtica dioica and Valerianella eriocarpa) and their cultivated relatives in central Italy were compared. The aims of the study were (i) to reveal the metabolic profile of particular bioactive metabolites present in some unusual food species by using a simple method of analysis, (ii) to quantify and compare the amount of polyphenolic metabolites in wild and cultivated plants and (iii) to evaluate the effect of growing conditions on polyphenolic variability. Data were subjected to statistical analysis

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Section: Introductionmentioning

confidence: 99%

Comparative evaluation of flavonoid content in assessing quality of wild and cultivated vegetables for human consumption

et al. 2007

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“…The basic knowledge that has been obtained over the years is mainly related to three observed phenomena. The first is the observation made by Radhakrishnan & Cooke (1969), that the average polarization position angle (PA) swings across the pulse profile in a way that can be explained by the geometrical rotating vector model, in which the position angle is tied to the direction of the magnetic field lines. As the emission beam of the pulsar sweeps past the line of sight of the observer, an observed swinging PA is a natural consequence.…”

Section: Introductionmentioning

confidence: 99%

An investigation of the absolute circular polarization in radio pulsars

Karastergiou¹,

Johnston²

2004

Monthly Notices of the Royal Astronomical Society

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In most pulsars, the circularly polarized component, Stokes $V$, is weak in the average pulse profiles. By forming the average profile of $|V|$ from single pulses we can distinguish between pulsars where $V$ is weak in the individual pulses and those where large $V$ of variable handedness is observed from one pulse to the other. We show how $|V|$ profiles depend on the signal-to-noise ratio of $V$ in the single pulses and demonstrate that it is possible to simulate the observed, broad distributions of $V$ by assuming a model where $|V|$ is distributed around a mean value and the handedness of $V$ is permitted to change randomly. The $|V|$ enhanced profiles of 13 pulsars are shown, 5 observed at 1.41 GHz and 8 observed at 4.85 GHz, to complement the set in Karastergiou et al. (2003b). It is argued that the degree of circular polarization in the single pulses is related to the orthogonal polarization mode phenomenon and not to the classification of the pulse components as cone or core.Comment: Accepted for publication in MNRA

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“…The plant is also used for treatment of type-2 diabetes mellitus patients [8] . Different pharmacologic effects of this plant are antiinflammatory, analgesic [6] , antioxidant [9][10][11] , potassium channel opener and blood pressure modifier [12] , as well as neuropharmacological [13,14] , wound healing [15] , antibacterial [16] and antipyretic effects [17] . The relaxant effect of this plant was studied on skeletal muscles [18] and smooth muscle of small intestine [19] .…”

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Portulaca olerace Affects Muscarinic Receptors of Guinea Pig Tracheal Smooth Muscle

Hashemzehi¹,

Khazdair²

2016

pharmaceutical-sciences

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Hashemzehi, et al.: Effect of Portulaca oleracea on Musacrinic ReceptorsThe relaxant effect of Portulaca oleracea L. on tracheal smooth muscles has been shown. The effect of the plant on muscarinic receptors of tracheal smooth muscles as one possible mechanism responsible for its relaxant effect was examined. Concentration response curves to methacholine were performed in the presence of three concentrations of aqueous-ethanol extract from aerial part of the plant (0.25, 0.50 and 1.00 mg/ml), 10 nM atropine, and saline. The values of EC 50 (effective concentration causing 50% of maximum response) and CR-1 ((EC 50 of test solutions/EC 50 of saline)-1) were measured. The study was done using three designs as non-incubated (group 1), incubated tissues with propranolol and chlorpheniramine (group 2) and incubated tissues with propranolol (group 3). Concentration-response curves to methacholine were shifted to the right and EC50 methacholine were significantly higher in the presence of atropine, medium and highest extract concentrations in all groups and its low concentration in group 3 compared to saline. In addition, EC 50 methacholine in the presence of high extract concentration (27.00±2.12) in group 2 was greater than its low (10.33±1.54) and medium (16.83±2.52) concentrations (p<0.05). The values of the CR-1 obtained in the presence of all extract concentrations in all groups were lower than that of atropine (P<0.05 to P<0.001). An inhibitory effect for the extract of P. oleracea on muscarinic receptors of tracheal smooth muscles was shown and a histamine (H 1 ) receptor blockade was also suggested.Key words: Portulaca oleracea, muscarinic receptor, tracheal smooth muscle, inhibitory effect, aqueousethanol extract Portulaca oleracea L. is an annual succulent which may reach 15.75 inches in height with alternate leaves clustered at stem joints; the yellow flower plant grows in different areas of the world including north and northwest of Iran [1] . Main active constituents of P. oleracea are omega-3 fatty acid, α-linolenic acid and eicosa-pentaenoic acid. This plant also contains vitamins (mainly vitamins A, C and some vitamin B) [2,3] . The plant also contains organic acids such as citric, maleic, cyanuric, caffeic acid as well as flavonoids, coumarins, and glycosides [4] .P. oleracea has several therapeutic effects including diuretic, antiascorbic, antipyretic, antiinflammatory [5][6][7] . The plant is also used for treatment of type-2 diabetes mellitus patients [8] . Different pharmacologic effects of this plant are antiinflammatory, analgesic [6] , antioxidant [9][10][11] , potassium channel opener and blood pressure modifier [12] , as well as neuropharmacological [13,14] , wound healing [15] , antibacterial [16] and antipyretic effects [17] . The relaxant effect of this plant was studied on skeletal muscles [18] and smooth muscle of small intestine [19] . Our previous studies also showed relaxant effect of the plant on tracheal smooth muscle [20] and the possible mechanism of this effect for this plant [21]...

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Neuropharmacological actions of Portulaca oleracea V. sativa

Cited by 71 publications

References 3 publications

Comparative evaluation of flavonoid content in assessing quality of wild and cultivated vegetables for human consumption

Comparative evaluation of flavonoid content in assessing quality of wild and cultivated vegetables for human consumption

An investigation of the absolute circular polarization in radio pulsars

Portulaca olerace Affects Muscarinic Receptors of Guinea Pig Tracheal Smooth Muscle

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