Neuroprotective effect of thiamine-producing lactic acid bacteria in a murine Parkinsonian model

Abstract

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by deterioration and loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc), resulting in motor deficits. Many studies have...

Effect of Lacticaseibacillus paracasei strain Shirota supplementation on clinical responses and gut microbiome in Parkinson's disease

“…2 There has been a surge in awareness of the association between gut microbiota and PD. [3][4][5][6] As evidence is accumulating on the effects of gut microbiota on disease development and progression, another course of action has been recognized in relation to the potential usage of microbiota-based therapeutic strategies in PD. Consequently, microbiota-targeted interventions, including the administration of probiotics, have increasingly been evaluated.…”