Neuropsychiatric effects of caffeine

Winston, A. P.; Hardwick, Elizabeth; Jaberi, Neema

doi:10.1192/apt.11.6.432

Cited by 92 publications

(80 citation statements)

References 61 publications

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“…Pesquisas mostram que o café, além da cafeína, apresenta muitos outros compostos bioativos como a vitamina B-3, ácidos clorogêni-cos, quinídeos (formados na torra do café a partir dos ácidos clorogênicos) dentre centenas de outros, a maioria volátil, que precisam ser mais bem estudados (MONTEIRO; TRUGO, 2005;WINSTON;HARDWICK;JABERI, 2005;TOCI;FARAH;TRUGO, 2006). Várias pesquisas mostram que o consumo de café pode ajudar a amenizar diversas doenças neurológicas crônicas como o mal de Parkinson e Alzheimer, doenças de origem metabólica como doenças no fígado (cirrose e carcinoma hepatocelular), diabetes tipo 2 e doenças cardiovasculares (WINSTON;HARDWICK;JABERI, 2005;ANDERSEN, 2006;DE LAU;BRETELER, 2006;HIGDON;FREI, 2006;PEREIRA;PARKER;FOLSOM, 2006). Johnson et al (2002) sugerem que pode haver um efeito positivo do consumo de café na velocidade de raciocínio nas pessoas idosas, e o trabalho de Kawachi et al (1996) Entre os métodos utilizados para a determinação da atividade antioxidante de compostos orgânicos, encontrase o método espectrofotométrico baseado na redução do radical estável DPPH .…”

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Análise de compostos bioativos, grupos ácidos e da atividade antioxidante do café arábica (Coffea arabica) do cerrado e de seus grãos defeituosos (PVA) submetidos a diferentes torras

Morais¹,

Aquino²,

Nascimento³

et al. 2008

Ciênc. Tecnol. Aliment.

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O Brasil apresenta um parque cafeeiro complexo e diversificado, dispõe de grandes extensões de terra de diferentes altitudes e produz, conseqüentemente, uma grande variedade de tipos de bebidas, o que o favorece em relação aos outros países concorrentes. Além disso, o País lidera o processo de desenvolvimento tecnológico, com destaque para a irrigação, fertirrigação e mecanização NAKAZONE, 2004). Na produção do café arábica, o Brasil de destaca por possuir o menor custo de produção e alta produtividade, o que lhe garante a competitividade no mercado internacional. AbstractThis work reports the results of the investigation of bioactive compounds (chlorogenic acids, trigonelline, caffeine, total phenolics, and proanthocyanidins), total acid groups, and the antioxidant activity of the Arabian coffee (Coffea arabica) from the Brazilian cerrado (vast tropical savannah) (Minas Gerais state) and its defective beans (Black, green, and sour beans). The samples were prepared using three roasting degrees: light (180 ± 10 °C; 6,0 ± 1,0 minutes), medium (180 ± 10 °C; 8,0 ± 1,0 minutos), and dark (180 ± 10 °C; 10,0 ± 1,0 minutes). Considering the average of the three roasts per coffee and defective beans, the difference observed for the content of all constituents listed above was not significant (p > 0,05). Exceptions are the content of acid hydroxyl groups, which were slightly greater in the coffee defective beans and the content of caffeine, calculated using the semi-quantitative method, which was higher in the coffee itself. Both the coffee and its defective beans presented scavenging activity against DPPH . radical; however, the coffee antioxidant activity was always higher. The variations observed in the content of caffeine, total phenols, proanthocyanidins, phenolic acid groups, trigonelline, and chlorogenic acid levels can not explain the higher antioxidant activity observed for the medium roasted coffee (EC50 of 2,3 mg.mg -1 of DPPH . ). Keywords: DPPH . ; EC50; savannah coffee; roasted coffee. ResumoO presente trabalho estudou os compostos bioativos (ácidos clorogênicos, trigonelina, cafeína, fenóis totais e proantocianidinas), grupos hidroxila ácidos e atividade antioxidante de um café arábica proveniente do Cerrado Mineiro e de seu PVA (grãos pretos, verdes e ardidos). As amostras foram preparadas nas torras clara (180 ± 10 °C; 6,0 ± 1,0 minutos), média (180 ± 10 °C; 8,0 ± 1,0 minutos) e escura (180 ± 10 °C; 10,0 ± 1,0 minutos). Considerando-se a média das três torras do café e do PVA, a diferença observada no teor de todos os constituintes acima não foi significativa (p > 0,05), exceto com o teor de grupos hidroxila ácidos que foi ligeiramente superior no PVA e cafeína calculada pelo método semiquantitativo que foi superior no café. Portanto, dentre esses constituintes, os compostos com grupos ácidos seriam os únicos que poderiam contribuir para explicar a grande diferença de sabor existente entre o café de grãos sadios e o de PVA. Tanto o café como o PVA apresentaram atividade seqüestradora do radical DPPH . nas...

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Análise de compostos bioativos, grupos ácidos e da atividade antioxidante do café arábica (Coffea arabica) do cerrado e de seus grãos defeituosos (PVA) submetidos a diferentes torras

Morais¹,

Aquino²,

Nascimento³

et al. 2008

Ciênc. Tecnol. Aliment.

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“…It also increases the period of wakefulness and can lengthen the time taken to fall asleep at night if large amounts of caffeine are taken in the evening. (10) In general, more than 200 mg of caffeine (approximately three or more caffeinated drinks) needs to be consumed in order for sleep to be significantly affected.…”

Section: Introductionmentioning

confidence: 99%

The prevalence of fatigue and associated health and safety risk factors among taxi drivers in Singapore

Lim¹,

Chia²

2015

smedj

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INTRODUCTIONDriver fatigue is one of the biggest health and safety concerns within the road transport sector. This study aimed to determine the prevalence of fatigue among taxi drivers in Singapore, to better understand the general working and health conditions of this group of people, and to determine the risk factors associated with fatigued driving. METHODSA total of 340 taxi drivers were randomly selected for participation in a self-administered questionnaire survey, which included height and weight measurements. The response rate was 68.2%. The survey consisted of four main categories: personal particulars; social habits; work patterns; and sleep profile. The Epworth Sleepiness Scale was used to estimate the level of daytime sleepiness and fatigue. Multiple logistic regression analysis was used to estimate the adjusted odd ratios and 95% confidence intervals associated with risk factors related to fatigue among taxi drivers.RESULTS A high proportion of taxi drivers were obese and had self-reported hypertension, diabetes mellitus and high cholesterol. Driver fatigue was associated with very poor/poor self-rating of quality of sleep, having an additional parttime job, drinking three or more caffeinated drinks daily, and driving more than 10 hours a day. CONCLUSIONWe hope that the findings of the present study will improve awareness of the work and health conditions of taxi drivers, and contribute toward efforts to achieve a healthier workforce. A lower prevalence of fatigued driving may lead to lower risks of road traffic accidents, decreased economic loss, increased productivity, and safer roads for all.

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“…In elderly people (>60 years old), Black tea consumption improves cognitive performances [10]. Importantly, caffeine improves sustained attention [5], mood and reduces fatigue [11][12][13], improves motor-skill performance in tasks such as a simulated driving task [14] and improves handwriting [15]. Caffeine at a dose of 200-250 mg improves attention in visual search task [16].…”

Section: Introductionmentioning

confidence: 99%

The effect of black tea on human cognitive performance in a cognitive test battery

et al. 2017

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Background: Black Tea is a widely consumed drink in the world. Evidence suggest Black Tea has stimulatory effect on humans. We investigated the effect of Black Tea on cognition using a cognitive test battery. Methods: Participants (n = 32) were fasted overnight for 10 h and restrained from caffeine and other stimulant drugs for 14 days prior to participation. We randomly assigned participants into either an experimental (n = 16) or a control (n = 16) group. Experimental group consumed 250 ml of Black Tea (BT) while control group was received equal volume of water (W). Participants were tested on the following cognitive tasks: executive function, sustained attention, memory (memory span, immediate, delayed, working memory) and arithmetic calculation task. Conclusions: BT consumption speeded the performance, improved memory, reduced number of errors in the various cognitive tasks. Our results further showed that even in small volume of BT consumption can speed up cognitive processing.

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Neuropsychiatric effects of caffeine

Cited by 92 publications

References 61 publications

Análise de compostos bioativos, grupos ácidos e da atividade antioxidante do café arábica (Coffea arabica) do cerrado e de seus grãos defeituosos (PVA) submetidos a diferentes torras

Análise de compostos bioativos, grupos ácidos e da atividade antioxidante do café arábica (Coffea arabica) do cerrado e de seus grãos defeituosos (PVA) submetidos a diferentes torras

The prevalence of fatigue and associated health and safety risk factors among taxi drivers in Singapore

The effect of black tea on human cognitive performance in a cognitive test battery

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