Neuropsychological assessment in pediatric oncology survivorship care: utilization of services, results of evaluation, and educational and behavioral health outcomes

Oswald, Kaitlin; Bitensky, Dylan; Stuchell, E.; Edmonds, Amy T; Richard, Annette; Hodges, Elise K.; Heinrich, Kimberley

doi:10.1007/s00520-021-06401-8

Cited by 6 publications

(4 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study reveals that parents are beleaguered the diverse symptoms of cognitive impairment exhibited by children with cancer.Different children with cancer display impairments in distinct cognitive domains,with the most signi cant impact observed in areas of verbal communication, executive function,and attention.These impairments have severe negative consequences on the children's normal learning and daily lives,aligning with the ndings of numerous prior studies [29][30][31] .The reasons for these impairments are diverse,encompassing factors such as the type of cancer, treatment methods, and medications used for each child 32 .Furthermore,the current situation regarding the cognitive impairment of children with cancer is not optimistic, given the lack of screening and cognitive rehabilitation services speci cally tailored to their needs 33 .Research suggests 34 that early identi cation and targeted intervention for cognitive impairments in children with cancer can promote the recovery of their cognitive functions and enhance their long-term quality of life. Therefore, it is particularly crucial to establish a precise and highly speci c system for the identi cation and intervention of cognitive impairment in children with cancer, who constitute a special group.…”

Section: Strengthening and Interventions Boosts Cancer Kids' Cognitiv...mentioning

confidence: 55%

Parents' Distress & Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study

Liu,

Xu,

Shen

et al. 2024

Preprint

View full text Add to dashboard Cite

Cancer-related Cognitive impairment is one of the common complications in children with cancer, yet our understanding of their experience with cognitive deficits remains limited.From the perspective of parents, this study aims to understand the distress and demands faced by children with cancer-related cognitive dysfunction, in order to provide references for developing targeted intervention strategies for these children.This study used a purposeful sampling method to conduct semi-structured interviews with the parents of 18 children with cancer-related cognitive impairment. The transcripts were analyzed using Colaizzi's method. Three categories and 11 subcategories were obtained from the data analysis.(a)Parents face multiple distressing symptoms of cognitive in children,including speech communication difficulties, impaired executive function,attention deficit, and intellectual disability.(b)Presistent negative emotions,including anxiety and worry,complaints and resentment,negative avoidance and positive experiences after psychological adjustment.(c)Multiple needs, including the need for disease information, the need for professional management, and an urgent need for more external support.Parents of children with cancer-related cognitive impairments are faced with the burden of multiple symptoms, coupled with significant confusion and demands regarding the symptoms of cognitive dysfunction. It is imperative for medical professionals to strengthen the dissemination of information related to cancer-associated cognitive impairments, while promptly recognizing and intervening in related symptoms. Rational allocation of resources, establishment of targeted support systems, and enhancing social acceptance are strategies that policymakers may consider.These efforts hold immense significance, as they play a pivotal role in elevating the cognitive capabilities and enhancing the overall quality of life for children afflicted with cancer.

show abstract

Section: Strengthening and Interventions Boosts Cancer Kids' Cognitiv...mentioning

confidence: 55%

Parents' Distress & Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study

Liu,

Xu,

Shen

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…The goal in prospectively evaluating hearing and cognition is to facilitate early referral and intervention. CCS must be connected with evidence-based rehabilitation interventions and other academic or behavioral supports based on testing recommendations ( 27 , 31 ). Developing, testing, and implementing cognitive rehabilitation interventions in clinical practice must be prioritized given the paucity of effective cognitive interventions for CCS ( 32 , 33 ).…”

Section: Discussionmentioning

confidence: 99%

Children with non-central nervous system tumors treated with platinum-based chemotherapy are at risk for hearing loss and cognitive impairments

L’Hotta,

Spence,

Varughese

et al. 2024

Front. Pediatr.

View full text Add to dashboard Cite

BackgroundChildhood cancer survivors (CCS) with chemotherapy induced sensorineural hearing loss (SNHL) are at risk for neurocognitive impairments. The purpose of this study was to determine the relationship between SNHL and cognitive function among CCS.ProcedureInclusion: non-CNS solid tumor diagnosis; history of platinum chemotherapy (cisplatin and/or carboplatin); 8–17 years of age; off anti-cancer treatment for ≥6 months; and English speaking. Exclusion: history of intrathecal chemotherapy, cranial radiation, or baseline neurocognitive disorder. Participants completed the NIH Toolbox Cognition Battery at enrollment. T-tests were used to compare participants with normal hearing to those with hearing loss and the total sample with established Toolbox normative data (mean: 50; SD: 10).ResultsFifty-seven individuals enrolled; 52 completed full cognitive testing. Participants were on average 12.2 years of age and 7.0 years since treatment completion. Twenty-one participants (40%) received cisplatin, 27 (52%) carboplatin, and 4 (8%) received both. Fifteen participants (29%) demonstrated SNHL based on the better ear. CCS, regardless of the presence or absence of SNHL, demonstrated significantly lower mean cognitive skills compared to the normative sample in attention, executive function, language- vocabulary and oral reading, processing speed, and fluid, crystallized and total composite scores (all p < 0.01). Participants with SNHL had significantly lower crystallized composite (vocabulary, oral reading) than those with normal hearing (41.9 vs. 47.2, p < 0.05, Cohen's d = 0.62).ConclusionsCCS at risk for platinum induced hearing loss but without cranial radiation or intrathecal chemotherapy exposure demonstrate impaired cognitive skills and those with SNHL demonstrate lower crystallized composite scores.

show abstract

“…Our findings indicate differences between children with CNS and leukemia. As these difficulties may be distinct, but still do not reach the threshold for (neuro-)developmental diagnoses, this might interfere with the provision of adequate and necessary treatments and support offers ( 48 ). Therefore, the difficulties could be particularly addressed in support offers during aftercare.…”

Section: Discussionmentioning

confidence: 99%

Reintegration into school, kindergarten and work in families of childhood cancer survivors after a family-oriented rehabilitation program

Inhestern,

Nasse,

Krauth

et al. 2024

Front. Pediatr.

View full text Add to dashboard Cite

ObjectiveTo describe the situation of childhood cancer survivors and their parents before and one year after a family-oriented rehabilitation program (FOR) and to identify factors influencing reintegration.MethodsWe included parents of children diagnosed with leukemia or central nervous system tumor. We assessed parental functioning using the functioning subscale of the Ulm Quality of Life Inventory for Parents (ULQIE) and children's school/kindergarten related quality of life (parental assessment, subscale KINDL-R). Descriptive analyses, group comparisons and multiple regression analyses on data of 285 parents of 174 children diagnosed with leukemia or central nervous system tumor.ResultsParents reported changes in their work situation (e.g., reduction of working hours) due to their child's diagnosis. Parental functioning increased significantly over time. Children's leukemia diagnosis and shorter time since the end of treatment were associated with higher functioning in parents one year after FOR. Parents reported difficulties in the child's work pace, concentration, stress resilience and empathy. The school/kindergarten-related quality of life (QoL) of the children was lower than in the general population. One year after FOR, most children reintegrated fully in school/kindergarten, partly with support (e.g., integration assistant). No significant predictors for children's reintegration were identified.DiscussionParents and children experience major changes in their work/school/kindergarten life. One year after FOR most parents reported a reintegration of their children, however the children's school/kindergarten-related QoL remained below average compared to norm values. Even after rehabilitation families of childhood cancer survivors might benefit from psychosocial and practical support offers to support families with the reintegration into work/school/kindergarten.

show abstract

Neuropsychological assessment in pediatric oncology survivorship care: utilization of services, results of evaluation, and educational and behavioral health outcomes

Cited by 6 publications

References 27 publications

Parents' Distress & Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study

Parents' Distress & Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study

Children with non-central nervous system tumors treated with platinum-based chemotherapy are at risk for hearing loss and cognitive impairments

Reintegration into school, kindergarten and work in families of childhood cancer survivors after a family-oriented rehabilitation program

Contact Info

Product

Resources

About

Neuropsychological assessment in pediatric oncology survivorship care: utilization of services, results of evaluation, and educational and behavioral health outcomes

Cited by 6 publications

References 27 publications

Parents' Distress &amp; Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study

Parents' Distress &amp; Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study

Children with non-central nervous system tumors treated with platinum-based chemotherapy are at risk for hearing loss and cognitive impairments

Reintegration into school, kindergarten and work in families of childhood cancer survivors after a family-oriented rehabilitation program

Contact Info

Product

Resources

About

Parents' Distress & Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study

Parents' Distress & Demands for Children with Cancer-Related Cognitive Impairment in Western China: A qualitative study