Neuropsychological performance of patients with soft bipolar spectrum disorders

Abstract

Our data suggest that patients with SBP differ from patients with UP not only in external validators (e.g., family history of bipolar disorder) and hypomanic symptoms, but also in neuropsychological performance and that the profiles of cognitive functioning were different across bipolar I disorder and 'bipolar II spectrum' that subsumes bipolar II disorder and SBP.

Bipolar disorder in Asia: Illness course and contributing factors

“…Comorbid borderline personality and a rapid disappearance of depressive symptoms are also seen as indicators of soft BD-II in recurrent depressive disorder patients similar to that reported from other regions of the World (Akiskal et al, 1995;Henry et al, 1999;Utsumi et al, 2006). A recent study from this region found that 'soft' bipolar patients fare well in working memory and processing speed when compared to the BD-I and BD-II patients (Lin et al, 2015). The study furthers our understanding of BD that the 'soft' bipolar individuals could represent a different endophenotype in bipolar spectrum disorders.…”

A systematic review on neuropsychological function in bipolar disorders type I and II and subthreshold bipolar disorders—something to think about

“…First, we give a more detailed description of all of the cognitive tasks and domains used in each of these studies (Table 2), and then we present an in depth review of the most relevant domains ( Table 3). 23 9 BDI 84/25% BDII No comorbidity controlled for 64% of overall patient group but no mention of difference between groups Aminoff et al 1 14 Not mentioned No comorbidity controlled for AP not mentioned Sparding 24 12 73%v7% No comorbidity controlled for AP not mentioned Lin et al 25 12 Next, we present accounts of each cognitive domain in the Figures 2-7 to give a more in depth review and clear answer as to whether (i) neurocognitive dysfunction in BP-II is similar to BP-I in each cognitive domain and (ii) whether these deficits exist in subsyndromal disorders SBP. Due to the limited amount of studies and to provide a more transparent account of the neuropsychological profile of (SBP), we have divided the results as follows: (i) comparison of neuropsychological functioning between BP-I and BP-II and (ii) neuropsychological functioning in SBP.…”

Are major depression and bipolar disorder neuropsychologically distinct? A meta-analysis of comparative studies

“…No data on these variables are available for the subgroup of subjects achieving remission after follow-up. d Only the data corresponding to 'strict MDD' were included to estimate effect sizes from the study by Lin et al [49].…”