“…Quantified Diameters of ON and CSF Sheath During Straight Gaze (0°) and 30°A bduction mean values 1,2,4,[13][14][15]17,18,24,25. Diameters between 1.9 mm and 3.5 mm (ON) and between 2.9 mm and 4.4 mm (CSF sheath) can be found in literature, which are similar to the results given in…”
supporting
confidence: 86%
“…8,[15][16][17][18] Such techniques are highly sensitive to motion of the eyes that can considerably degrade the accuracy of measurement due to loss of spatial resolution or make it even impossible due to motion artifacts. Thus, these sequences may be sufficient for morphologic imaging, but for quantification a rapid MRI technique that can accurately quantify the ON and CSF sheath diameter within 1.5 seconds was developed.…”
A novel and fast magnetic resonance imaging approach for imaging the optic nerve and the surrounding cerebrospinal fluid sheath is presented. The method provides high contrast between the nerve and cerebrospinal fluid and allows for accurate quantification of the optic nerve and its cerebrospinal fluid sheath diameter within 1.5 seconds scan time. Results of a volunteer study illustrate that measurements can reliably be performed even in the distal part of the intraorbital optic nerve track. Accuracy of quantification of the new technique is demonstrated by the assessment of changes in the optic nerve and CSF sheath diameter between straight gaze and 30 degrees abduction.
“…Quantified Diameters of ON and CSF Sheath During Straight Gaze (0°) and 30°A bduction mean values 1,2,4,[13][14][15]17,18,24,25. Diameters between 1.9 mm and 3.5 mm (ON) and between 2.9 mm and 4.4 mm (CSF sheath) can be found in literature, which are similar to the results given in…”
supporting
confidence: 86%
“…8,[15][16][17][18] Such techniques are highly sensitive to motion of the eyes that can considerably degrade the accuracy of measurement due to loss of spatial resolution or make it even impossible due to motion artifacts. Thus, these sequences may be sufficient for morphologic imaging, but for quantification a rapid MRI technique that can accurately quantify the ON and CSF sheath diameter within 1.5 seconds was developed.…”
A novel and fast magnetic resonance imaging approach for imaging the optic nerve and the surrounding cerebrospinal fluid sheath is presented. The method provides high contrast between the nerve and cerebrospinal fluid and allows for accurate quantification of the optic nerve and its cerebrospinal fluid sheath diameter within 1.5 seconds scan time. Results of a volunteer study illustrate that measurements can reliably be performed even in the distal part of the intraorbital optic nerve track. Accuracy of quantification of the new technique is demonstrated by the assessment of changes in the optic nerve and CSF sheath diameter between straight gaze and 30 degrees abduction.
“…The obex is the most caudal point in the fourth ventricle at the medullary level, where ventricle narrows to become the central canal of the spinal cord. The LGN is consistently found in the coronal cut of the brain passing through the PC and obex, oriented according to the PC/obex plane . The LGN borders were delineated on the coronal section, starting with the slice in the PC/obex reference plane and the planes anterior and posterior to the reference one.…”
We found microstructural alterations in visual pathways in nondemented PD patients with hallucination, mainly in first-order neurons and atrophy in the lateral geniculate body where the retinal ganglion cells synapse to second-order neurons. Afferent visual pathway degeneration may occur in a trans-synaptic way in PD. Further studies warrant to be conducted.
“…1) 26,44,45 : It was located above the hippocampus and the ambient cistern, beneath and lateral to the thalamus, and medial to the optic radiations. All subjects' MRI data were submitted to a neurologist (YK) to rule other pathologies that are known to present as glaucoma.…”
On high-resolution 7.0-T MRI, LGN volumes in POAG patients are significantly smaller than those of healthy subjects. Furthermore, in patients, LGN volume was found to be significantly correlated with GC-IPL thickness of the contralateral eye.
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