1999
DOI: 10.1054/jhsb.1999.0249
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Neurothekeoma of the Hand

Abstract: Neurothekeomas are rare, benign connective tissue tumours probably of Schwann cell origin. We report an unusual case of a neurothekeoma involving the hand. Histological examination revealed characteristic myxoid nodules with spindle shaped cells. The immunocytochemical reaction for S-100 protein and neuron-specific enolase was positive. Complete excision proved curative as the tumour was well encapsulated.

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Cited by 15 publications
(7 citation statements)
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“…3,6,7,8,13,17,24,29,32 All 40 tumors in our series tested for S-100 protein were unequivocally positive. We think that neurothekeoma, as presently defined and diagnosed, is a ''mixed bag'' of unrelated tumors.…”
Section: Discussionmentioning
confidence: 68%
See 1 more Smart Citation
“…3,6,7,8,13,17,24,29,32 All 40 tumors in our series tested for S-100 protein were unequivocally positive. We think that neurothekeoma, as presently defined and diagnosed, is a ''mixed bag'' of unrelated tumors.…”
Section: Discussionmentioning
confidence: 68%
“…3,7,8,13,17,22,24,29,32 This neoplasm is, without doubt, a peripheral nerve sheath tumor. 3,7,8,13,17,22,24,29,32 This neoplasm is, without doubt, a peripheral nerve sheath tumor.…”
Section: Discussionmentioning
confidence: 97%
“…5 O tratamento indicado é resseção cirúrgica, completa, da lesão e parece ser o tratamento definitivo, sem que cause lesão neurológica. [6][7][8][9][10] A resseção incompleta leva a recidiva e invasão local. 5 Uma vez que os neurotequeomas do tipo mixoide e celular são lesões benignas, não há registros de metastização e esse tipo de lesão não beneficia de radioterapia ou quimioterapia adjuvante.…”
Section: Discussionunclassified
“…[6] The myxoid type is characterized by a high degree of myxomatous changes, low cellularity with scattered spindle cells, and is well circumscribed. There may also be multinucleated giant cells and the lesions characteristically stain positively for S-100, collagen type IV, and nerve growth factor receptor but are negative for epithelial membrane antigen or markers of histiocytic differentiation.…”
Section: Discussionmentioning
confidence: 99%