Neutralization of toxic effects of different crude jellyfish venoms by an extract of Ipomoea pes-caprae (L.) R. Br.

Pongprayoon, U.; Bohlin, Lars; Wasuwat, S.

doi:10.1016/0378-8741(91)90133-x

Cited by 31 publications

(18 citation statements)

References 10 publications

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“…(Tao et al, 2008) Widely reported e.g. (Tao et al, 2008) L Pain from jelly fish 1B (Wasuwat, 1970;Isaacs, 1987;Pongprayoon et al, 1991;Bandaranayake, 1999;Tao et al, 2008 (Cribb and Cribb, 1984;Vaughan, 1986;Lassak and McCarthy, 2008) (Leiper and Hauser, 1984;Isaacs, 1987;Budhiraja et al, 1999) Widely reported e.g. (Carson et al, 2006) (Low, 1990;Hiddins, 1999;Daw et al, 2007;Lassak and McCarthy, 2008) (Agnew and Lauren, 1991;Daw et al, 2007;Lassak and McCarthy, 2008) Agnew and Lauren, 1991;Daw et al, 2007;Lassak and McCarthy, 2008) Rumex sp.…”

Section: Rutaceaementioning

confidence: 98%

An ethnobotanical study of medicinal plants used by the Yaegl Aboriginal community in northern New South Wales, Australia

Packer

Brouwer

Harrington

et al. 2012

Journal of Ethnopharmacology

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Section: Rutaceaementioning

confidence: 98%

An ethnobotanical study of medicinal plants used by the Yaegl Aboriginal community in northern New South Wales, Australia

Packer

Brouwer

Harrington

et al. 2012

Journal of Ethnopharmacology

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“…pes-caprae exhibited insulinogenic, hypoglycemic (Khan et al, 1994), anti-haemolytic (Pongprayoon et al, 1991a) antispasmodic (Pongprayoon et al, 1989;, antiinflammatory (Pongprayoon et al, 1992b) and anti-histamine (Wasuwat, 1970) activities.…”

Section: Ipomoea Parasitica (Kunth) G Donmentioning

confidence: 99%

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Meira¹,

Silva²,

David³

et al. 2012

Rev. bras. farmacogn.

170

120

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Approximately 600-700 species of Ipomoea, Convolvulaceae, are found throughout tropical and subtropical regions of the world. Several of those species have been used as ornamental plants, food, medicines or in religious ritual. The present work reviews the traditional uses, chemistry and biological activities of Ipomoea species and illustrates the potential of the genus as a source of therapeutic agents. These species are used in different parts of the world for the treatment of several diseases, such as, diabetes, hypertension, dysentery, constipation, fatigue, arthritis, rheumatism, hydrocephaly, meningitis, kidney ailments and infl ammations. Some of these species showed antimicrobial, analgesic, spasmolitic, spasmogenic, hypoglycemic, hypotensive, anticoagulant, anti-infl ammatory, psychotomimetic and anticancer activities. Alkaloids, phenolics compounds and glycolipids are the most common biologically active constituents from these plant extracts.

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“…Phytochemical studies of I. pes-caprae have identified the presence of steroids, terpenoids, alkaloids and flavonoids (Souza et al, 2000), β-damascenone, E-phytol, betulinic acid, triperpenos, α-and β-amyrin, acetates, isoquerticinas (Pongprayoon, Bohlin, Wasuwat, 1991;Souza et al, 2000) and isoprenoids (Krogh et al, 1999). Although triterpenes and flavonoids have been described in the literature as inhibitors of human lymphocytes proliferation (Moiteiro et al, 2001;Brochado et al, 2003;Arokiyaraj et al, 2007), the action of these compounds appears to be inhibited by other compounds with immunostimulating effects, such as alkaloids (Sheng, Bryngelsson, Pero, 2000), since the results obtained showed an increase in cell proliferation and possibly activation of T lymphocytes.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of the proliferative activity of methanol extracts from six medicinal plants in murine spleen cells

Zandonai

Coelho

Ferreira

et al. 2010

Braz. J. Pharm. Sci.

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A number of natural compounds have been used as immunomodulatory agents, enabling the function of the immune system to be modified by stimulating or suppressing it. There has been increasing interest in the study of therapeutic action of plant extracts regarding their immunomodulatory activity. The aim of this study was to identify and evaluate the action of extracts of the medicinal plants Calophyllum brasiliense, Ipomoea pes-caprae, Matayba elaeagnoides, Maytenus robusta, Rubus imperialis and Vernonia scorpioides on the development of spleen cells from mice, using the in vitro cellular proliferation assay. The cells, obtained by mechanical rupture of mice spleen (5x10 4 cells/mL), were incubated with methanol extracts (10, 50, 100 and 200 mg/mL) and phytohemagglutinin (PHA, 5 mg/mL). The basal control for proliferation consisted of cells alone, while the positive control consisted of cells and PHA. The cell culture was kept at 37 o C in 5% CO 2 for 72 hours, and cell proliferation was revealed by the blue tetrazolium reduction assay (MTT). The results were expressed as percentage of growth and were analyzed using the Kruskal-Wallis and Mann-Whitney tests. The C. brasiliense, I. pes-caprae and M. elaeagnoides extracts showed dose-dependent induction of cell proliferation, with a significant increase in cell proliferation (p<0.03) and percentage growth of 88.2%, 73.1% and 52.7%, respectively, suggesting T lymphocyte stimulation. By contrast, M. robusta, R. imperialis and V. scorpioides extracts showed significance only with a negative percentage of growth, suggesting inhibition of cell proliferation (p<0.04). Further biomonitoring studies will enable the fractions and isolated substances responsible for the immunomodulatory activities to be identified. Várias substâncias de origem natural têm sido utilizadas como agentes imunomoduladores, permitindo modificar a função do sistema imune e propiciando o estudo de atividades terapêuticas de extratos de plantas. Este trabalho objetivou identificar a atividade imunomodulatória dos extratos de seis plantas medicinais da flora brasileira, Calophyllum brasiliense, Ipomoea pes-caprae, Matayba elaeagnoides, Maytenus robusta, Rubus imperialis e Vernonia scorpioides, sobre a proliferação de células esplênicas de camundongos. As células esplênicas murinas obtidas por ruptura mecânica do baço (5x14 3 células/mL) foram incubadas com os extratos metanólicos das plantas (10, 50, 100, 200 mg/mL) e fito-hemaglutinina (PHA, 5 mg/mL). O controle basal de proliferação foi constituído de células apenas e o controle positivo formado por células e PHA. O cultivo celular foi mantido a 37 o C, 5% de CO 2 , 72 horas, com quantificação da proliferação celular pelo ensaio de redução do azul de tetrazólio. Os resultados expressos em percentagem de crescimento foram analisados pelos testes de Kruskal-Wallis e Mann-Whitney. Os extratos de C. brasiliense, I. pes-caprae e M. elaeagnoides mostraram indução dose-dependente da proliferação celular (p<0,03), com percentagem de crescimento de, respecti...

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Neutralization of toxic effects of different crude jellyfish venoms by an extract of Ipomoea pes-caprae (L.) R. Br.

Cited by 31 publications

References 10 publications

An ethnobotanical study of medicinal plants used by the Yaegl Aboriginal community in northern New South Wales, Australia

An ethnobotanical study of medicinal plants used by the Yaegl Aboriginal community in northern New South Wales, Australia

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Evaluation of the proliferative activity of methanol extracts from six medicinal plants in murine spleen cells

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