Neutrophilic eccrine hidradenitis in two neutropaenic patients

Keane, Fergus; Munn, S.E.; Buckley, D. A.; Hopster, Deborah J.; Mufti, Ghulam J.; Vivier, Anthony du

doi:10.1046/j.1365-2230.2001.00785.x

Cited by 20 publications

(25 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other cases have been reported in the literature. Six patients receiving induction chemotherapy with cytarabine for acute myelogenous leukemia presented facial plaques with similar descriptions [5, 6, 7, 8]. However, observations regarding the evolution of the plaques are poor except for 3 of the cases in whom the lesions slowly extended across the face [5, 7] or neck-trunk region [7].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Classic Clinical Case: Neutrophilic Eccrine Hidradenitis

Copaescu¹,

Castilloux

Chababi-Atallah³

et al. 2013

Case Rep Dermatol

View full text Add to dashboard Cite

Background: Neutrophilic eccrine hidradenitis (NEH) is a rare condition described mostly in adult patients receiving chemotherapy for acute myelogenous leukemia. When it affects the facial region, it can mimic cellulitis and delay the diagnostic, thus proper recognition is essential. Objective: This article describes a classic case of NEH. We will review the diagnostic, the differential diagnostic (mostly cellulitis) and the management of this condition. Methods: After a literature review, the patient's file was properly studied in order to portray a clear picture of this condition. Medical photographs and appropriate physical examination upon presentation are also included. Results: The diagnostic for NEH was suggested by the clinical presentation and confirmed histopathologically (skin biopsy). Conclusion: The diagnostic of NEH is essential in order to prevent multiple unnecessary antibiotics.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Associations other than malignancy or chemotherapy have been made in the literature. The treatment is symptomatic and mainly involves topical or systemic corticosteroids [1, 7, 9]. Nonetheless, corticosteroids should be used with caution in neutropenic patients.…”

Section: Discussionmentioning

confidence: 99%

A Classic Clinical Case: Neutrophilic Eccrine Hidradenitis

Copaescu¹,

Castilloux

Chababi-Atallah³

et al. 2013

Case Rep Dermatol

View full text Add to dashboard Cite

show abstract

“…30 In patients with severe neutropenia, the neutrophilic infiltrate may be absent; however, necrosis of the eccrine epithelium is typical. 31 NEH is a selflimiting adverse reaction. 31 Frequently, the process resolves within a month, without treatment.…”

Section: Neutrophilic Eccrine Hidradenitismentioning

confidence: 99%

“…31 NEH is a selflimiting adverse reaction. 31 Frequently, the process resolves within a month, without treatment. In other chemotherapy cycles, 60% of the patients may relapse.…”

Section: Neutrophilic Eccrine Hidradenitismentioning

confidence: 99%

Reações tegumentares adversas relacionadas aos agentes antineoplásicos: parte I

Sanches

Brandt

Moure

et al. 2010

An. Bras. Dermatol.

View full text Add to dashboard Cite

Abstract:The local and systemic treatment of tumors can cause changes in the skin, mucous membranes, hair and nails. Accurate diagnosis and appropriate treatment of side effects require knowledge about the patterns of the most common adverse reactions to drugs the patient may be using. The dermatologist must be familiar with the manifestations of certain soft tissue neoplasms, as well as with the adverse mucocutaneous forms of cancer treatment. Keyword s: Chemotherapy, adjuvant; Drug therapy; Drug therapy, combination; Skin; Skin abnormalities; Skin pigmentation Resumo: O tratamento local e sistêmico das neoplasias pode causar alterações na pele, membranas mucosas, cabelos e unhas. O diagnóstico preciso e o tratamento adequado destes efeitos colaterais requerem conhecimento dos padrões das reações adversas mais comuns para as medicações que o paciente está utilizando. O dermatologista deve estar familiarizado com as manifestações tegumentares das neoplasias, bem como com os efeitos adversos mucocutâneos dos tratamentos antineoplásicos.

show abstract

“…Neutrophilic eccrine hidradenitis is also a recurrent papulopustular eruption seen in patients undergoing chemotherapy; however, in neutrophilic eccrine hidradenitis histology shows a neutrophilic infiltrate causing degeneration of the eccrine gland. 6 The exact cause of EPF is unknown. Numerous studies have implicated chemotactic agents, interleukin-5, cyclooxygenase-generated metabolites, and intercellular adhesion molecule (ICAM)-1.…”

Section: Eosinophilic Pustular Folliculitis Induced By Chemotherapymentioning

confidence: 99%