New Approaches in Preventing Premature Rupture of Membranes in Pregnant Women With Varicose Disease

Abstract

Aims: To investigate modern methods to prevent premature rupture of membranes by the use of chlorhexidine in pregnant women with varicose disease. Methods: The data of 39 pregnant women with varicose disease, who delivered between 2014 and 2016 at Maternity Hospital No. 3, Zaporozhye were analyzed using SPSS software. Patients were divided in 3 groups according to their medical history, complications during pregnancy, childbirth and postpartum period. The 1st group consisted of 13 pregnant women who did not receive prenatal vaginal douching with chlorhexidine; the 2nd group consisted of 13 patients with varicose disease, who received douching of birth canal with vaginal suppositories with chlorhexidine 1 time per day for 10 days before their delivery, but did not undergo a rehabilitation at the sanatorium; and the 3rd group had 13 pregnant women who received sanatorium rehabilitation at ''Veliki lug'' during the II. trimester of their pregnancy with the course of 1 chlorhexidine suppository per day for 10 days before delivery. Results: In the 1st group, the percentage of premature death was 61.5%; anemia and significant ultrasound markers were present in 46.2%; the percentage for the presence of hematometra was 38.5%; premature rupture of membranes, anomalies of labor and polyhydroamniosis were 30.8%; chorioamnionitis 15.4%; and intrauterine infection of fetus was 7.7%. In the 2nd group, anemia was present in 35%, 23.1% showed anomalies of labor; premature rupture of membranes, ultrasound markers, premature death, and hematometra were present in 15.4%. Whereas in the 3rd group, anemia and anomalies of labor were present in 15.4%, premature rupture of the membranes and premature death were present in 7.7% of the patients. Conclusion: With its broad antibacterial and antiviral effect, chlorhexidine in antiseptic form was found to be beneficial and it is found to promote the restoration of the vaginal microflora.