Aims: To perform a comparative analysis of individual clinical and laboratory indicators in the differential diagnosis of conditionally limited and generalized forms of postpartum septic complications. Methods: The study included 34 patients at Gynecology Department of the Zaporizhzhia Regional Clinical Hospital from 2013 to 2016 with postpartum purulent-septic diseases. Patients were divided into 2 groups. Group I consisted of 15 women who were diagnosed with a conditionally limited postpartum purulent-inflammatory disease (endometritis). Group II included 19 women with generalized forms of postpartum purulent-inflammatory diseases (peritonitis, sepsis). For the diagnosis of Multiple Organ Failure due to sepsis, we used the Sequential (Sepsis-Related) Organ Failure Assessment and quick Sequential (Sepsis-Related) Organ Failure Assessment. The differences between the first and second group were assessed by using the Mann-Whitney U test and STATISTICA Version 10. Results: Body temperature was increased in all 34 patients. The average heart rate in group I was 91.6 ± 8.35 beats/ min and 102.26 ± 16.42 beats/min in group II. The average respiratory rate was 19.07 ± 2.49 breaths/min in group I and 24.16 ± 5.09 breaths/min in group II. In group I, none of the patients scored a total of two or more points on the Sequential (Sepsis-Related) Organ Failure Assessment and quick Sequential (Sepsis-Related) Organ Failure Assessment scales; in group II, there were 5 (26.32%) patients who had scored two points or more on the Sequential (Sepsis-Related) Organ Failure Assessment scale; and 2 (10.53%) patients had scored 2 points or more in the quick Sequential (Sepsis-Related) Organ Failure Assessment scale. Conclusion: Clinical cases of postpartum period with inflammation of uterus and signs of multiple organ failure should be; regarded as a septic state, assessed by the Sequential (Sepsis-Related) Organ Failure Assessment scale as they require urgent medical help.

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Aims: To investigate modern methods to prevent premature rupture of membranes by the use of chlorhexidine in pregnant women with varicose disease. Methods: The data of 39 pregnant women with varicose disease, who delivered between 2014 and 2016 at Maternity Hospital No. 3, Zaporozhye were analyzed using SPSS software. Patients were divided in 3 groups according to their medical history, complications during pregnancy, childbirth and postpartum period. The 1st group consisted of 13 pregnant women who did not receive prenatal vaginal douching with chlorhexidine; the 2nd group consisted of 13 patients with varicose disease, who received douching of birth canal with vaginal suppositories with chlorhexidine 1 time per day for 10 days before their delivery, but did not undergo a rehabilitation at the sanatorium; and the 3rd group had 13 pregnant women who received sanatorium rehabilitation at ''Veliki lug'' during the II. trimester of their pregnancy with the course of 1 chlorhexidine suppository per day for 10 days before delivery. Results: In the 1st group, the percentage of premature death was 61.5%; anemia and significant ultrasound markers were present in 46.2%; the percentage for the presence of hematometra was 38.5%; premature rupture of membranes, anomalies of labor and polyhydroamniosis were 30.8%; chorioamnionitis 15.4%; and intrauterine infection of fetus was 7.7%. In the 2nd group, anemia was present in 35%, 23.1% showed anomalies of labor; premature rupture of membranes, ultrasound markers, premature death, and hematometra were present in 15.4%. Whereas in the 3rd group, anemia and anomalies of labor were present in 15.4%, premature rupture of the membranes and premature death were present in 7.7% of the patients. Conclusion: With its broad antibacterial and antiviral effect, chlorhexidine in antiseptic form was found to be beneficial and it is found to promote the restoration of the vaginal microflora.