New aspect of studying the mechanisms of development of the lungs ventilation capacity disorders in children with bronchial asthma

Abstract

Purpose. Study of the pathogenetic role of the polymorphism of the ACTN3 gene (actinin, alpha 3) rs1815739 in the development of lungs ventilation capacity disorders in children with bronchial asthma. 157 pronounced in asthma attacks, which can lead to less pronounced disorders of lungs ventilation capacity. Conclusions. The study of ACTN3 (actinin, alpha 3) rs1815739 gene polymorphism showed that the C / C and C / T genotypes were associated with impaired lung ventilation in children with bronchial asthma.