New Developments in Tissue Engineering of Microvascular Prostheses

Vindigni, Vincenzo; Abatangelo, Giovanni; Bassetto, Franco

doi:10.5772/24899

Cited by 3 publications

(2 citation statements)

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“…The scaffolds are the essential component of the tissue engineering, which is made up of biomaterial having porosity, as the scaffold is a temporary biodegradable framework for organ and tissue regeneration. The scaffold mimics the extracellular matrix, and pores helps them to achieve cell adhesion and proliferation − and simultaneously, growth factors are also incorporated in the scaffold as they are essential for cell regeneration. , The tissue engineering is the restoration of damaged tissue with the help of cell culture. , The scaffold can be of biodegradable and nonbiodegradable materials, and we have discussed the biodegradable scaffold in this Review.…”

Section: Introductionmentioning

confidence: 99%

Progress in the Advancement of Porous Biopolymer Scaffold: Tissue Engineering Application

Ambekar

Kandasubramanian

2019

Ind. Eng. Chem. Res.

165

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Tissue engineering is a derivative of biomedical engineering, which deals with the repair and regeneration of organs or their tissues. Cell-embedded porous polymeric scaffolds unveil proficiency in rectifying the mechanical trauma of skin, bone erosion, and neurodegenerative diseases like spinal cord injury. Archetypically, pristine cell-based biomaterial scaffolds are utilized; however, investigations over time have validated that incorporation of additives such as silver nanoparticles or bioactive glass augments antimicrobial characteristics in conjunction with cell adherence. An ideal scaffold should exhibit ease of processability, biocompatibility, biodegradability, noncytotoxicity, and excellent mechanical property, and these properties can be achieved with biodegradable polymers. Researchers have extensively explored copious advanced as well as conventional fabrication technologies such as electrospinning, 3D and 4D bioprinting, among others, for contouring of porous polymeric scaffolds in tissue-engineering functions like skin, bone, liver, cardiac, and neural tissue regeneration, which we have consolidated and discussed in the presented Review.

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Section: Introductionmentioning

confidence: 99%

Progress in the Advancement of Porous Biopolymer Scaffold: Tissue Engineering Application

Ambekar

Kandasubramanian

2019

Ind. Eng. Chem. Res.

165

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“…The development of tissue-engineered microvascular prostheses is still a challenge, and many approaches are currently being investigated [8]. Biopolymers such as collagen and elastin have been used to engineer vascular constructs [9,10].…”

Section: Introductionmentioning

confidence: 99%

Optimization of poly(l-lactic acid)/segmented polyurethane electrospinning process for the production of bilayered small-diameter nanofibrous tubular structures

Ballarin

Caracciolo

Blotta

et al. 2014

Materials Science and Engineering: C

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Glucose diffusion in tissue engineering membranes and scaffolds

Suhaimi

Das

2016

Reviews in Chemical Engineering

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Tissue engineering has evolved into an exciting area of research due to its potential in regenerative medicine. The shortage of organ donors as well as incompatibility between patient and donor pose an alarming concern. This has resulted in an interest in regenerative therapy where the importance of understanding the transport properties of critical nutrients such as glucose in numerous tissue engineering membranes and scaffolds is crucial. This is due to its dependency on successful tissue growth as a measure of potential cure for health issues that cannot be healed using traditional medical treatments. In this regard, the diffusion of glucose in membranes and scaffolds that act as templates to support cell growth must be well grasped. Keeping this in mind, this review paper aims to discuss the glucose diffusivity of these materials. The paper reviews four interconnected issues, namely, (i) the glucose diffusion in tissue engineering materials, (ii) porosity and tortuosity of these materials, (iii) the relationship between microstructure of the material and diffusion, and (iv) estimation of glucose diffusivities in liquids, which determine the effective diffusivities in the porous membranes or scaffolds. It is anticipated that the review paper would help improve the understanding of the transport properties of glucose in membranes and scaffolds used in tissue engineering applications.

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New Developments in Tissue Engineering of Microvascular Prostheses

Cited by 3 publications

References 50 publications

Progress in the Advancement of Porous Biopolymer Scaffold: Tissue Engineering Application

Progress in the Advancement of Porous Biopolymer Scaffold: Tissue Engineering Application

Optimization of poly(l-lactic acid)/segmented polyurethane electrospinning process for the production of bilayered small-diameter nanofibrous tubular structures

Glucose diffusion in tissue engineering membranes and scaffolds

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