New generation of oxide-based nanoparticles for the applications in early cancer detection and diagnostics

Abstract

<jats:title>Abstract</jats:title><jats:p>Hereby the possible applications of oxide nanoparticles in the cancer diagnostics and therapy are presented. Cancer diseases are nowadays one of the most common causes of death in the highly-developed countries. Discussed will be the current clinical cancer detection methods with their shortcomings. The role of nanomedicine in cancer medicine and the potential applications of nanoparticles debated in the literature will be critically evaluated. In the second part, the most common methods for the nanoparticle synthesis will be discussed. Finally, the system for cancer detection based on the enhanced permeation-retention of multimodal high-k oxide nanoparticles doped with lanthanides will be proposed for both for themagnetic resonance imaging (non-gadolinium contrast agents) and for fluorescence guided biopsy and surgery.</jats:p>

Recent Development in Metallic Nanoparticles for Breast Cancer Therapy and Diagnosis

“…[2] These materials can function as drug carriers, contrast agents for imaging, photothermal materials, photoacoustic compounds, and enhancer of radiation dose. [1,2] The medical imaging techniques applied in breast diagnostics is magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), single photon emission computerized tomography (SPECT), optical imaging (OM), ultrasound (US), and photoacoustic imaging. Various cancer therapeutic approaches using metallic nanoparticles include photothermal therapy (PTT), photodynamic therapy (PDT), chemotherapy and immunotherapy.…”

Biodegradable Zinc Oxide Nanoparticles Doped with Iron as Carriers of Exogenous Iron in the Living Organism

“…Nowadays, nanostructures have become greatly popular among scientists as innovative tools for various biomedical purposes [ 24 , 25 , 26 , 27 ]. Nanoparticles reveal completely different features compared to substances in bulk or their ionic equivalents, including different transcellular transport systems.…”

A review of passive methods in microchannel heat sink application through advanced geometric structure and nanofluids: Current advancements and challenges

“…In recent years, nanotechnology was applied to further improve the performance of hydrothermal. According to Nanotechnology journal database, nanotechnology is widely used in various fields such as medical [22][23][24], biomedical especially for cancer detection [25][26][27] and treatment [28,29], bone regeneration [30][31][32], vaccine [33] and drug [34] delivery system, central nervous system [35], biological imaging [36], and membrane proteins analysis [37,38]. However, studies on the nanofluid application for thermal management [39] are limited.…”