New Insights Into the Skin Microbial Communities and Skin Aging

Li, Zichao; Bai, Xiaozhi; Peng, Tingwei; Yi, Xiaowei; Luo, Liang; Yang, Jizhong; Liu, Jiaqi; Wang, Yunchuan; He, Ting; Wang, Xujie; Zhu, Huayu; Wang, Hongtao; Tao, Ke; Zhang, Zheng; Su, Linlin; Hu, Dahai

doi:10.3389/fmicb.2020.565549

Cited by 56 publications

(70 citation statements)

References 60 publications

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“…The species diversity of the skin microbiome progresses at least until the age of eight. The number of Staphylococcus or Streptococcus species decreases, and the amount of Actinobacteria and Proteobacteria species increases [ 51 , 52 ]. In pre-pubertal children, a greater diversity of fungal species than in adolescents and adults is observed.…”

Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

“…In pre-pubertal children, a greater diversity of fungal species than in adolescents and adults is observed. However, the greatest variety of fungi characterizes the skin microbiome of middle-aged people [ 15 , 52 , 53 ].…”

Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

“…Microorganisms inhabiting the human skin may impact the processes that are essential for skin aging, including the regulation of immune functions, resistance to ultraviolet radiation, and the biosynthesis and metabolism of substances related to progressive aging [ 52 ]. The effect of microorganisms depends on the age of the individual and the colonization area ( Figure 3 ).…”

Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

“…The effect of microorganisms depends on the age of the individual and the colonization area ( Figure 3 ). While the presence of Streptococcus in the children’s skin microbiome is a positive phenomenon, the same bacteria negatively affect the skin condition of the elderly [ 52 ]. Additionally, natural changes in the structure and topography of the skin, that accompany the aging process, for example, wrinkle formation, influence the skin microbiome composition.…”

Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

“…On the other hand, some bacteria can protect the skin from the destructive effect of UV radiation. Li et al [ 52 ] found that Cyanobacteria and Lactobacillus on the skin surface decreased the intensity of pigmentation and the occurrence of damage related to so-called photoaging.…”

Section: Living and Working Environmentmentioning

confidence: 99%

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Human Skin Microbiome: Impact of Intrinsic and Extrinsic Factors on Skin Microbiota

et al. 2021

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The skin is the largest organ of the human body and it protects the body from the external environment. It has become the topic of interest of researchers from various scientific fields. Microorganisms ensure the proper functioning of the skin. Of great importance, are the mutual relations between such microorganisms and their responses to environmental impacts, as dysbiosis may contribute to serious skin diseases. Molecular methods, used for microorganism identification, allow us to gain a better understanding of the skin microbiome. The presented article contains the latest reports on the skin microbiota in health and disease. The review discusses the relationship between a properly functioning microbiome and the body’s immune system, as well as the impact of internal and external factors on the human skin microbiome.

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Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

Section: The Skin Microbiome In Different Stages Of Human Developmmentioning

confidence: 99%

Section: Living and Working Environmentmentioning

confidence: 99%

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Human Skin Microbiome: Impact of Intrinsic and Extrinsic Factors on Skin Microbiota

et al. 2021

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Black soldier fly (Hermetia illucens L.): A potential small mighty giant in the field of cosmeceuticals

Lai‐Foenander,

Kuppusamy,

Manogoran

et al. 2024

Health Science Reports

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Background and AimsNatural products are widely used in the pharmaceutical and cosmetics industries due to their high‐value bioactive compounds, which make for “greener” and more environmentally friendly ingredients. These natural compounds are also considered a safer alternative to antibiotics, which may result in antibiotic resistance as well as unfavorable side effects. The development of cosmeceuticals, which combine the cosmetic and pharmaceutical fields to create skincare products with therapeutic value, has increased the demand for unique natural resources. The objective of this review is to discuss the biological properties of extracts derived from larvae of the black soldier fly (BSF; Hermetia illucens), the appropriate extraction methods, and the potential of this insect as a novel active ingredient in the formulation of new cosmeceutical products. This review also addresses the biological actions of compounds originating from the BSF, and the possible association between the diets of BSF larvae and their subsequent bioactive composition.MethodsA literature search was conducted using PubMed and Google Scholar to identify and evaluate the various biological properties of the BSF.ResultsOne such natural resource that may be useful in the cosmeceutical field is the BSF, a versatile insect with numerous potential applications due to its nutrient content and scavenging behavior. Previous research has also shown that the BSF has several biological properties, including antimicrobial, antioxidant, anti‐inflammatory, and wound healing effects.ConclusionGiven the range of biological activities and metabolites possessed by the BSF, this insect may have the cosmeceutical potential to treat a number of skin pathologies.

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Bacterial taxa predictive of hyperpigmented skins

Zanchetta

Vilanova

Jarrin

et al. 2022

Health Science Reports

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Background and Aims Dark spots, brown spots, or hyperpigmented spots (HPS) are oval or irregular brown areas of skin. Their emergence is associated with dysregulation of the immune system, and may also be caused by a deficiency in stromal cell‐derived factor‐1, leading to perturbed melanogenesis and accumulation of melanosomes within neighboring keratinocytes. The skin microbiota (living microorganisms present on the surface of the skin) is known to play essential roles in maintaining skin homeostasis and in regulating the immune system. Here, we investigated whether the microbiota could play a role in the emergence of HPS. Methods The clinical study involved 38 European women, selected from among 74 volunteers. Participants were divided into two groups depending on the spot areas measured on their faces. The study was designed to avoid conflicting factors: both groups presented similar skin pH, hydration, transepidermal water loss, and sebum levels. The two cohorts were also age‐matched, with a mean of 29‐years‐old for both. Results Alpha‐diversity of the microbiota was similar for the two groups. On skins with more HPS, seven bacterial genera were identified in significantly higher proportions and included opportunistic pathogens and inflammatory bacteria. Six bacterial genera, including bacteria showing antioxidant and anti‐UV properties, were identified in significantly higher proportions on less spotted skins. Cross‐domain association networks revealed distinct co‐occurrences of genera between the two groups, suggesting nonidentical community structures and exchanges, depending on the HPS status. Conclusion Our results reveal specific microbiota composition and networks on skins based on HPS status. Changes could alter communication with the immune system, leading to the emergence of dark spots. As an essential part of the overall skin ecosystem, and through its interaction with the skin matrix, the skin microbiota and its maintenance could be considered a new target for skincare applications.

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New Insights Into the Skin Microbial Communities and Skin Aging

Cited by 56 publications

References 60 publications

Human Skin Microbiome: Impact of Intrinsic and Extrinsic Factors on Skin Microbiota

Human Skin Microbiome: Impact of Intrinsic and Extrinsic Factors on Skin Microbiota

Black soldier fly (Hermetia illucens L.): A potential small mighty giant in the field of cosmeceuticals

Bacterial taxa predictive of hyperpigmented skins

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